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Items: 1 to 20 of 1135

1.

Repurposing antitubercular agent isoniazid for treatment of prostate cancer.

Lv Q, Wang D, Yang Z, Yang J, Zhang R, Yang X, Wang M, Wang Y.

Biomater Sci. 2018 Nov 23. doi: 10.1039/c8bm01189c. [Epub ahead of print]

PMID:
30468220
2.

Experimental evidence for re-secretion of PGE2 across rat alveolar epithelium by OATP2A1/SLCO2A1-mediated transcellular transport.

Nakanishi T, Takashima H, Uetoko Y, Komori H, Tamai I.

J Pharmacol Exp Ther. 2018 Nov 12. pii: jpet.118.249789. doi: 10.1124/jpet.118.249789. [Epub ahead of print]

3.

Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1.

Schäfer AM, Bock T, Meyer Zu Schwabedissen HE.

Mol Pharm. 2018 Nov 9. doi: 10.1021/acs.molpharmaceut.8b00631. [Epub ahead of print]

PMID:
30380886
4.

Comprehensive evaluation of the utility of 20 endogenous molecules as biomarkers of OATP1B inhibition compared to rosuvastatin and coproporphyrin I.

Barnett S, Ogungbenro K, Menochet K, Shen H, Humphreys GW, Galetin A.

J Pharmacol Exp Ther. 2018 Oct 12. pii: jpet.118.253062. doi: 10.1124/jpet.118.253062. [Epub ahead of print]

5.

Exhaustive exercise decreases renal organic anion transporter 3 function.

Bunprajun T, Yuajit C, Noitem R, Chatsudthipong V.

J Physiol Sci. 2018 Oct 3. doi: 10.1007/s12576-018-0641-5. [Epub ahead of print]

PMID:
30284192
6.

Renal expression of organic anion transporters is modified after mercuric chloride exposure: Gender-related differences.

Hazelhoff MH, Bulacio RP, Chevalier A, Torres AM.

Toxicol Lett. 2018 Oct 1;295:390-396. doi: 10.1016/j.toxlet.2018.07.016. Epub 2018 Jul 18.

PMID:
30031051
7.

JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats.

Wen S, Wang C, Huo X, Meng Q, Liu Z, Yang S, Zhu Y, Sun H, Ma X, Liu K.

Toxicol Lett. 2018 Oct 1;295:195-204. doi: 10.1016/j.toxlet.2018.06.1220. Epub 2018 Jun 28.

PMID:
29964132
8.

Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes.

Vildhede A, Kimoto E, Rodrigues AD, Varma MVS.

Mol Pharm. 2018 Aug 6;15(8):3227-3235. doi: 10.1021/acs.molpharmaceut.8b00320. Epub 2018 Jun 25.

PMID:
29906129
9.

Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey.

Kosa RE, Lazzaro S, Bi YA, Tierney B, Gates D, Modi S, Costales C, Rodrigues AD, Tremaine LM, Varma MV.

Drug Metab Dispos. 2018 Aug;46(8):1179-1189. doi: 10.1124/dmd.118.081794. Epub 2018 Jun 7.

PMID:
29880631
10.

Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro.

Liu Q, Liu Z, Huo X, Wang C, Meng Q, Sun H, Sun P, Peng J, Ma X, Liu K.

Biomed Pharmacother. 2018 Jul;103:915-922. doi: 10.1016/j.biopha.2018.04.122. Epub 2018 Apr 24.

PMID:
29710508
11.

Hypouricemic Effects of Armillaria mellea on Hyperuricemic Mice Regulated through OAT1 and CNT2.

Yong T, Chen S, Xie Y, Chen D, Su J, Shuai O, Hu H, Zuo D, Liang D.

Am J Chin Med. 2018;46(3):585-599. doi: 10.1142/S0192415X18500301. Epub 2018 Mar 29.

PMID:
29595077
12.

Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate.

Qiu B, Xia B, Zhou Q, Lu Y, He M, Hasegawa K, Ma Z, Zhang F, Gu L, Mao Q, Wang F, Zhao S, Gao Z, Liao J.

Cell Res. 2018 Jun;28(6):644-654. doi: 10.1038/s41422-018-0032-8. Epub 2018 Mar 27.

PMID:
29588525
13.

High expression of SLCO2B1 is associated with prostate cancer recurrence after radical prostatectomy.

Terakawa T, Katsuta E, Yan L, Turaga N, McDonald KA, Fujisawa M, Guru KA, Takabe K.

Oncotarget. 2018 Feb 8;9(18):14207-14218. doi: 10.18632/oncotarget.24453. eCollection 2018 Mar 6.

14.

Renal outcomes with sodium glucose cotransporter 2 (SGLT2) inhibitor, dapagliflozin, in obese insulin-resistant model.

Jaikumkao K, Pongchaidecha A, Chueakula N, Thongnak L, Wanchai K, Chatsudthipong V, Chattipakorn N, Lungkaphin A.

Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2021-2033. doi: 10.1016/j.bbadis.2018.03.017. Epub 2018 Mar 20.

PMID:
29572114
15.

AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3.

Zhang J, Liu C, You G.

J Pharmacol Sci. 2018 Mar;136(3):142-148. doi: 10.1016/j.jphs.2018.01.006. Epub 2018 Feb 8.

16.

The activity of organic anion transporter-3: Role of dexamethasone.

Wang H, Liu C, You G.

J Pharmacol Sci. 2018 Feb;136(2):79-85. doi: 10.1016/j.jphs.2017.12.011. Epub 2018 Feb 2.

17.

Hyperuricemia and Progression of Chronic Kidney Disease: Role of Phenotype Transition of Renal Tubular and Endothelial Cells.

Kang DH.

Contrib Nephrol. 2018;192:48-55. doi: 10.1159/000484278. Epub 2018 Jan 23.

PMID:
29393109
18.

Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers.

Hamada Y, Ikemura K, Iwamoto T, Okuda M.

Pharmacology. 2018;101(3-4):176-183. doi: 10.1159/000485920. Epub 2018 Jan 19.

PMID:
29353278
19.

The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model.

Miyauchi S, Masuda M, Kim SJ, Tanaka Y, Lee KR, Iwakado S, Nemoto M, Sasaki S, Shimono K, Tanaka Y, Sugiyama Y.

Drug Metab Dispos. 2018 Mar;46(3):259-267. doi: 10.1124/dmd.117.077115. Epub 2018 Jan 3.

PMID:
29298773
20.

Influence of genetic polymorphisms on mycophenolic acid pharmacokinetics and patient outcomes in renal transplantation.

Guo M, Wang ZJ, Yang HW, Meng L, Tan RY, Gu M, Wei JF.

Curr Drug Metab. 2017 Dec 27. doi: 10.2174/1389200219666171227201608. [Epub ahead of print]

PMID:
29283068

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