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Items: 1 to 20 of 47

1.

A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.

Huang W, Rainbow DB, Wu Y, Adams D, Shivakumar P, Kottyan L, Karns R, Aronow B, Bezerra J, Gershwin ME, Peterson LB, Wicker LS, Ridgway WM.

J Immunol. 2018 Jan 1;200(1):147-162. doi: 10.4049/jimmunol.1701087. Epub 2017 Nov 20.

2.

Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8+ T cell activation.

Ma HD, Ma WT, Liu QZ, Zhao ZB, Liu MZ, Tsuneyama K, Gao JM, Ridgway WM, Ansari AA, Gershwin ME, Fei YY, Lian ZX.

J Autoimmun. 2017 Mar;78:19-28. doi: 10.1016/j.jaut.2016.12.012. Epub 2017 Jan 24.

3.

Dual Roles of IFN-γ and IL-4 in the Natural History of Murine Autoimmune Cholangitis: IL-30 and Implications for Precision Medicine.

Syu BJ, Loh CE, Hsueh YH, Gershwin ME, Chuang YH.

Sci Rep. 2016 Oct 10;6:34884. doi: 10.1038/srep34884.

4.

Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance.

Bae HR, Leung PS, Tsuneyama K, Valencia JC, Hodge DL, Kim S, Back T, Karwan M, Merchant AS, Baba N, Feng D, Park O, Gao B, Yang GX, Gershwin ME, Young HA.

Hepatology. 2016 Oct;64(4):1189-201. doi: 10.1002/hep.28641. Epub 2016 Jun 15.

5.

Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice.

Yang GX, Sun Y, Tsuneyama K, Zhang W, Leung PS, He XS, Ansari AA, Bowlus C, Ridgway WM, Gershwin ME.

Clin Exp Immunol. 2016 Aug;185(2):154-64. doi: 10.1111/cei.12806. Epub 2016 Jun 6.

6.

Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens.

Arsenijevic A, Milovanovic M, Milovanovic J, Stojanovic B, Zdravkovic N, Leung PS, Liu FT, Gershwin ME, Lukic ML.

Sci Rep. 2016 Mar 21;6:23348. doi: 10.1038/srep23348.

7.

Chemokine and chemokine receptors in autoimmunity: the case of primary biliary cholangitis.

Choi J, Selmi C, Leung PS, Kenny TP, Roskams T, Gershwin ME.

Expert Rev Clin Immunol. 2016 Jun;12(6):661-72. doi: 10.1586/1744666X.2016.1147956. Epub 2016 Feb 25. Review.

8.

AAV-IL-22 modifies liver chemokine activity and ameliorates portal inflammation in murine autoimmune cholangitis.

Hsueh YH, Chang YN, Loh CE, Gershwin ME, Chuang YH.

J Autoimmun. 2016 Jan;66:89-97. doi: 10.1016/j.jaut.2015.10.005. Epub 2015 Nov 1.

9.

Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.

Yang JB, Wang YH, Yang W, Lu FT, Ma HD, Zhao ZB, Jia YJ, Tang W, Tsuneyama K, Ridgway WM, Gershwin ME, Lian ZX.

J Autoimmun. 2016 Jan;66:108-17. doi: 10.1016/j.jaut.2015.09.002. Epub 2015 Oct 1.

10.

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis.

Concepcion AR, Salas JT, Sáez E, Sarvide S, Ferrer A, Portu A, Uriarte I, Hervás-Stubbs S, Oude Elferink RP, Prieto J, Medina JF.

Oncotarget. 2015 Oct 6;6(30):28588-606. doi: 10.18632/oncotarget.5665.

11.

Th1 cytokines and chemokines in primary biliary cirrhosis.

Limongi F.

Clin Ter. 2015;166(2):e122-5. doi: 10.7417/T.2015.1834.

PMID:
25945445
12.

Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.

Chang CH, Chen YC, Zhang W, Leung PS, Gershwin ME, Chuang YH.

PLoS One. 2015 Mar 25;10(3):e0121320. doi: 10.1371/journal.pone.0121320. eCollection 2015.

13.

Adoptive cell transfer in autoimmune hepatitis.

Czaja AJ.

Expert Rev Gastroenterol Hepatol. 2015 Jun;9(6):821-36. doi: 10.1586/17474124.2015.1019470. Epub 2015 Feb 26.

PMID:
25719553
14.

Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis.

Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME.

Clin Exp Immunol. 2015 Jun;180(3):371-82. doi: 10.1111/cei.12581.

15.

Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice.

Kopec AK, Sullivan BP, Kassel KM, Joshi N, Luyendyk JP.

Toxicol Sci. 2014 Oct;141(2):515-23. doi: 10.1093/toxsci/kfu148. Epub 2014 Jul 23.

16.

Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.

Tanaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME.

Clin Exp Immunol. 2014 Nov;178(2):253-61. doi: 10.1111/cei.12415.

17.

Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα(-/-) mice.

Yao Y, Yang W, Yang YQ, Ma HD, Lu FT, Li L, Tao YY, Tsuneyama K, Zhang W, Friedman S, Gershwin ME, Lian ZX.

J Autoimmun. 2014 Jun;51:99-108. doi: 10.1016/j.jaut.2014.02.009. Epub 2014 Mar 17.

PMID:
24651036
18.

Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells.

Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM.

J Autoimmun. 2014 May;50:123-34. doi: 10.1016/j.jaut.2014.01.034. Epub 2014 Feb 18.

19.

Innate immunity drives xenobiotic-induced murine autoimmune cholangitis.

Chang CH, Chen YC, Yu YH, Tao MH, Leung PS, Ansari AA, Gershwin ME, Chuang YH.

Clin Exp Immunol. 2014 Aug;177(2):373-80. doi: 10.1111/cei.12298.

20.

Reovirus type-2-triggered autoimmune cholangitis in extrahepatic bile ducts of weanling DBA/1J mice.

Nakashima T, Hayashi T, Tomoeda S, Yoshino M, Mizuno T.

Pediatr Res. 2014 Jan;75(1-1):29-37. doi: 10.1038/pr.2013.170. Epub 2013 Oct 11.

PMID:
24121424

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