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Items: 1 to 20 of 263

1.

The presence of genetic risk variants within PTPN2 and PTPN22 is associated with intestinal microbiota alterations in Swiss IBD cohort patients.

Yilmaz B, Spalinger MR, Biedermann L, Franc Y, Fournier N, Rossel JB, Juillerat P, Rogler G, Macpherson AJ, Scharl M.

PLoS One. 2018 Jul 2;13(7):e0199664. doi: 10.1371/journal.pone.0199664. eCollection 2018.

2.

Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling.

Baek M, Kim M, Lim JS, Morales LD, Hernandez J, Mummidi S, Williams-Blangero S, Jang IS, Tsin AT, Kim DJ.

Cell Death Dis. 2018 Jun 28;9(7):730. doi: 10.1038/s41419-018-0781-9.

3.

Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2.

Luo N, Formisano L, Gonzalez-Ericsson PI, Sanchez V, Dean PT, Opalenik SR, Sanders ME, Cook RS, Arteaga CL, Johnson DB, Balko JM.

Oncoimmunology. 2018 Mar 6;7(6):e1438106. doi: 10.1080/2162402X.2018.1438106. eCollection 2018.

4.

Modulation of STAT3 phosphorylation by PTPN2 inhibits naïve pluripotency of embryonic stem cells.

Zhang Y, Ding H, Wang X, Ye SD.

FEBS Lett. 2018 May 24. doi: 10.1002/1873-3468.13112. [Epub ahead of print]

PMID:
29797458
5.

Molecular and clinical characterization of PTPN2 expression from RNA-seq data of 996 brain gliomas.

Wang PF, Cai HQ, Zhang CB, Li YM, Liu X, Wan JH, Jiang T, Li SW, Yan CX.

J Neuroinflammation. 2018 May 15;15(1):145. doi: 10.1186/s12974-018-1187-4.

6.

TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding.

Dodd GT, Lee-Young RS, Brüning JC, Tiganis T.

Diabetes. 2018 Jul;67(7):1246-1257. doi: 10.2337/db17-1485. Epub 2018 Apr 30.

PMID:
29712668
7.

HCV modifies EGF signalling and upregulates production of CXCR2 ligands: Role in inflammation and antiviral immune response.

Groepper C, Rufinatscha K, Schröder N, Stindt S, Ehlting C, Albrecht U, Bock HH, Bartenschlager R, Häussinger D, Bode JG.

J Hepatol. 2018 Apr 27. pii: S0168-8278(18)32013-0. doi: 10.1016/j.jhep.2018.04.005. [Epub ahead of print]

PMID:
29705238
8.

One for all and all for One: Improving replication of genetic studies through network diffusion.

Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Crovella M, Farrer LA, Kasif S.

PLoS Genet. 2018 Apr 23;14(4):e1007306. doi: 10.1371/journal.pgen.1007306. eCollection 2018 Apr.

9.

Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice.

Li Y, Zhou H, Wang F, Han L, Liu M, Li Y, Wang Z, Tang M, Zhang W, Zhong M.

Cell Physiol Biochem. 2018;46(1):118-132. doi: 10.1159/000488415. Epub 2018 Mar 21.

10.

25-Hydroxyvitamin D3 -enhanced PTPN2 positively regulates periodontal inflammation through the JAK/STAT pathway in human oral keratinocytes and a mouse model of type 2 diabetes mellitus.

Zhang P, Zhang W, Zhang D, Wang M, Aprecio R, Ji N, Mohamed O, Li Y, Ding Y, Wang Q.

J Periodontal Res. 2018 Jun;53(3):467-477. doi: 10.1111/jre.12535. Epub 2018 Mar 8.

PMID:
29516520
11.

Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease.

Zhang Q, Li H, Hou S, Yu H, Su G, Deng B, Qi J, Zhou C, Kijlstra A, Yang P.

Br J Ophthalmol. 2018 Jul;102(7):996-1002. doi: 10.1136/bjophthalmol-2017-310820. Epub 2018 Mar 3.

PMID:
29502070
12.

Role of PTPN2/22 polymorphisms in pathophysiology of Crohn's disease.

Sharp RC, Beg SA, Naser SA.

World J Gastroenterol. 2018 Feb 14;24(6):657-670. doi: 10.3748/wjg.v24.i6.657.

13.

PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.

Spalinger MR, Manzini R, Hering L, Riggs JB, Gottier C, Lang S, Atrott K, Fettelschoss A, Olomski F, Kündig TM, Fried M, McCole DF, Rogler G, Scharl M.

Cell Rep. 2018 Feb 13;22(7):1835-1848. doi: 10.1016/j.celrep.2018.01.052.

14.
15.

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.

Houtman M, Shchetynsky K, Chemin K, Hensvold AH, Ramsköld D, Tandre K, Eloranta ML, Rönnblom L, Uebe S, Catrina AI, Malmström V, Padyukov L.

J Autoimmun. 2018 Jun;90:28-38. doi: 10.1016/j.jaut.2018.01.003. Epub 2018 Feb 3.

16.

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles.

Smith MJ, Rihanek M, Wasserfall C, Mathews CE, Atkinson MA, Gottlieb PA, Cambier JC.

Diabetes. 2018 Apr;67(4):697-703. doi: 10.2337/db17-0937. Epub 2018 Jan 17.

PMID:
29343548
17.

Protein-altering variants of PTPN2 in childhood-onset Type 1A diabetes.

Okuno M, Ayabe T, Yokota I, Musha I, Shiga K, Kikuchi T, Kikuchi N, Ohtake A, Nakamura A, Nakabayashi K, Okamura K, Momozawa Y, Kubo M, Suzuki J, Urakami T, Kawamura T, Amemiya S, Ogata T, Sugihara S, Fukami M; Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes.

Diabet Med. 2018 Mar;35(3):376-380. doi: 10.1111/dme.13566. Epub 2018 Jan 3.

PMID:
29247561
18.

Ligand-Dependent Interaction of PPARδ With T-Cell Protein Tyrosine Phosphatase 45 Enhances Insulin Signaling.

Yoo T, Ham SA, Lee WJ, Hwang SI, Park JA, Hwang JS, Hur J, Shin HC, Han SG, Lee CH, Han DW, Paek KS, Seo HG.

Diabetes. 2018 Mar;67(3):360-371. doi: 10.2337/db17-0499. Epub 2017 Dec 12.

PMID:
29233935
19.

TC-PTP regulates the IL-7 transcriptional response during murine early T cell development.

Pike KA, Hatzihristidis T, Bussières-Marmen S, Robert F, Desai N, Miranda-Saavedra D, Pelletier J, Tremblay ML.

Sci Rep. 2017 Oct 16;7(1):13275. doi: 10.1038/s41598-017-13673-w.

20.

PTPN2: a tumor suppressor you want deleted?

Wiede F, Tiganis T.

Immunol Cell Biol. 2017 Nov;95(10):859-861. doi: 10.1038/icb.2017.70. Epub 2017 Oct 10. No abstract available.

PMID:
28994418

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