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Peroxisome proliferators-activated receptor gamma polymorphisms and colorectal cancer risk.

Liang X, Fan X, Tan K, Zhang L, Jian L, Yu L.

J Cancer Res Ther. 2018 Jun;14(Supplement):S306-S310. doi: 10.4103/0973-1482.235346.


Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets.

Liang YS, Qi WT, Guo W, Wang CL, Hu ZB, Li AK.

Food Nutr Res. 2018 May 11;62. doi: 10.29219/fnr.v62.1384. eCollection 2018.


Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARγ expression.

Lu ZH, Peng JH, Zhang RX, Wang F, Sun HP, Fang YJ, Wan DS, Pan ZZ.

Saudi J Biol Sci. 2018 Feb;25(2):372-376. doi: 10.1016/j.sjbs.2017.02.002. Epub 2017 Feb 14.


Anti-cancer Effects of MW-03, a Novel Indole Compound, by Inducing 15-Hydroxyprostaglandin Dehydrogenase and Cellular Growth Inhibition in the LS174T Human Colon Cancer Cell Line.

Seira N, Yanagisawa N, Suganami A, Honda T, Wasai M, Regan JW, Fukushima K, Yamaguchi N, Tamura Y, Arai T, Murayama T, Fujino H.

Biol Pharm Bull. 2017;40(10):1806-1812. doi: 10.1248/bpb.b17-00458.


Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.

Couch DG, Tasker C, Theophilidou E, Lund JN, O'Sullivan SE.

Clin Sci (Lond). 2017 Oct 25;131(21):2611-2626. doi: 10.1042/CS20171288. Print 2017 Nov 1.


Administration of geniposide ameliorates dextran sulfate sodium-induced colitis in mice via inhibition of inflammation and mucosal damage.

Zhang Z, Li Y, Shen P, Li S, Lu X, Liu J, Cao Y, Liu B, Fu Y, Zhang N.

Int Immunopharmacol. 2017 Aug;49:168-177. doi: 10.1016/j.intimp.2017.05.033. Epub 2017 Jun 5.


TR2 and TR4 Orphan Nuclear Receptors: An Overview.

Lin SJ, Yang DR, Yang G, Lin CY, Chang HC, Li G, Chang C.

Curr Top Dev Biol. 2017;125:357-373. doi: 10.1016/bs.ctdb.2017.02.002. Epub 2017 Apr 5. Review.


Deciphering the Roles of Thiazolidinediones and PPARγ in Bladder Cancer.

Chiu M, McBeth L, Sindhwani P, Hinds TD.

PPAR Res. 2017;2017:4810672. doi: 10.1155/2017/4810672. Epub 2017 Feb 28. Review.


A PPAR-gamma agonist protects from radiation-induced intestinal toxicity.

Mangoni M, Sottili M, Gerini C, Desideri I, Bastida C, Pallotta S, Castiglione F, Bonomo P, Meattini I, Greto D, Cappelli S, Di Brina L, Loi M, Biti G, Livi L.

United European Gastroenterol J. 2017 Mar;5(2):218-226. doi: 10.1177/2050640616640443. Epub 2016 Jul 8.


Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer.

Lecarpentier Y, Claes V, Vallée A, Hébert JL.

PPAR Res. 2017;2017:5879090. doi: 10.1155/2017/5879090. Epub 2017 Feb 19. Review.


Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction.

Duszka K, Picard A, Ellero-Simatos S, Chen J, Defernez M, Paramalingam E, Pigram A, Vanoaica L, Canlet C, Parini P, Narbad A, Guillou H, Thorens B, Wahli W.

Sci Rep. 2016 Nov 17;6:36937. doi: 10.1038/srep36937.


Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation.

Tylichová Z, Straková N, Vondráček J, Vaculová AH, Kozubík A, Hofmanová J.

J Nutr Biochem. 2017 Jan;39:145-155. doi: 10.1016/j.jnutbio.2016.09.006. Epub 2016 Sep 28.


Fatty acid-binding protein 1 is preferentially lost in microsatellite instable colorectal carcinomas and is immune modulated via the interferon γ pathway.

Wood SM, Gill AJ, Brodsky AS, Lu S, Friedman K, Karashchuk G, Lombardo K, Yang D, Resnick MB.

Mod Pathol. 2017 Jan;30(1):123-133. doi: 10.1038/modpathol.2016.170. Epub 2016 Sep 30.


Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy.

Park H, Ko SH, Lee JM, Park JH, Choi YH.

Yonsei Med J. 2016 Nov;57(6):1494-9. doi: 10.3349/ymj.2016.57.6.1494.


Proteomic characterization of peroxisome proliferator-activated receptor-γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype.

Milone MR, Pucci B, Colangelo T, Lombardi R, Iannelli F, Colantuoni V, Sabatino L, Budillon A.

Mol Oncol. 2016 Oct;10(8):1344-62. doi: 10.1016/j.molonc.2016.07.006. Epub 2016 Jul 25.


The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM.

Immunity. 2016 Aug 16;45(2):374-88. doi: 10.1016/j.immuni.2016.07.009. Epub 2016 Aug 2. Erratum in: Immunity. 2016 Sep 20;45(3):701-703.


Aldo-keto reductase 1B10 promotes development of cisplatin resistance in gastrointestinal cancer cells through down-regulating peroxisome proliferator-activated receptor-γ-dependent mechanism.

Matsunaga T, Suzuki A, Kezuka C, Okumura N, Iguchi K, Inoue I, Soda M, Endo S, El-Kabbani O, Hara A, Ikari A.

Chem Biol Interact. 2016 Aug 25;256:142-53. doi: 10.1016/j.cbi.2016.07.008. Epub 2016 Jul 11.


The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands.

Zurlo D, Ziccardi P, Votino C, Colangelo T, Cerchia C, Dal Piaz F, Dallavalle S, Moricca S, Novellino E, Lavecchia A, Colantuoni V, Lupo A.

Biochem Pharmacol. 2016 May 15;108:22-35. doi: 10.1016/j.bcp.2016.03.007. Epub 2016 Mar 17.


Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway.

Sarnelli G, Gigli S, Capoccia E, Iuvone T, Cirillo C, Seguella L, Nobile N, D'Alessandro A, Pesce M, Steardo L, Cuomo R, Esposito G.

Phytother Res. 2016 Jun;30(6):963-70. doi: 10.1002/ptr.5601. Epub 2016 Mar 1.


Chemopreventive action of non-steroidal anti-inflammatory drugs on the inflammatory pathways in colon cancer.

Ghanghas P, Jain S, Rana C, Sanyal SN.

Biomed Pharmacother. 2016 Mar;78:239-247. doi: 10.1016/j.biopha.2016.01.024. Epub 2016 Feb 2.


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