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Items: 1 to 20 of 3076


Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ.

Cheang WS, Wong WT, Wang L, Cheng CK, Lau CW, Ma RCW, Xu A, Wang N, Huang Y, Tian XY.

Pharmacol Res. 2018 Nov 29;139:384-394. doi: 10.1016/j.phrs.2018.11.041. [Epub ahead of print]


Erratum to "Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy".

Wagner KD, Vukolic A, Baudouy D, Michiels JF, Wagner N.

PPAR Res. 2018 Oct 29;2018:5480829. doi: 10.1155/2018/5480829. eCollection 2018.


Nuclear hormone receptors: Ancient 9aaTAD and evolutionally gained NCoA activation pathways.

Piskacek M, Havelka M, Jendruchova K, Knight A.

J Steroid Biochem Mol Biol. 2018 Nov 20. pii: S0960-0760(18)30465-5. doi: 10.1016/j.jsbmb.2018.11.008. [Epub ahead of print]


Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.

Michelet X, Dyck L, Hogan A, Loftus RM, Duquette D, Wei K, Beyaz S, Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, Nikolajczyk BS, Mills KHG, Brenner MB, Finlay D, Lynch L.

Nat Immunol. 2018 Dec;19(12):1330-1340. doi: 10.1038/s41590-018-0251-7. Epub 2018 Nov 12.


N-Acetylcysteine (NAC) Ameliorates Lipid-Related Metabolic Dysfunction in Bone Marrow Stromal Cells-Derived Adipocytes.

Raffaele M, Barbagallo I, Licari M, Carota G, Sferrazzo G, Spampinato M, Sorrenti V, Vanella L.

Evid Based Complement Alternat Med. 2018 Oct 17;2018:5310961. doi: 10.1155/2018/5310961. eCollection 2018.


Dietary Genistein Alleviates Lipid Metabolism Disorder and Inflammatory Response in Laying Hens With Fatty Liver Syndrome.

Lv Z, Xing K, Li G, Liu D, Guo Y.

Front Physiol. 2018 Oct 24;9:1493. doi: 10.3389/fphys.2018.01493. eCollection 2018.


Identification and Molecular Characterization of Peroxisome Proliferator-Activated Receptor δ as a Novel Target for Covalent Modification by 15-Deoxy-Δ12,14-prostaglandin J2.

Reddy AT, Lakshmi SP, Banno A, Reddy RC.

ACS Chem Biol. 2018 Nov 29. doi: 10.1021/acschembio.8b00584. [Epub ahead of print]


PPARδ agonist enhances colitis-associated colorectal cancer.

Zhou D, Jin J, Liu Q, Shi J, Hou Y.

Eur J Pharmacol. 2018 Nov 2;842:248-254. doi: 10.1016/j.ejphar.2018.10.050. [Epub ahead of print]


The Effect of Hypoxia and Metformin on Fatty Acid Uptake, Storage, and Oxidation in L6 Differentiated Myotubes.

Musutova M, Elkalaf M, Klubickova N, Koc M, Povysil S, Rambousek J, Volckaert B, Duska F, Trinh MD, Kalous M, Trnka J, Balusikova K, Kovar J, Polak J.

Front Endocrinol (Lausanne). 2018 Oct 17;9:616. doi: 10.3389/fendo.2018.00616. eCollection 2018.


Non-anthocyanin phenolics in cherry (Prunus avium L.) modulate IL-6, liver lipids and expression of PPARδ and LXRs in obese diabetic (db/db) mice.

Noratto GD, Lage NN, Chew BP, Mertens-Talcott SU, Talcott ST, Pedrosa ML.

Food Chem. 2018 Nov 15;266:405-414. doi: 10.1016/j.foodchem.2018.06.020. Epub 2018 Jun 5.


The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor.

Liu Y, Colby JK, Zuo X, Jaoude J, Wei D, Shureiqi I.

Int J Mol Sci. 2018 Oct 26;19(11). pii: E3339. doi: 10.3390/ijms19113339. Review.


Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells.

Zhang C, Deng J, Liu D, Tuo X, Yu Y, Yang H, Wang N.

Molecules. 2018 Oct 22;23(10). pii: E2723. doi: 10.3390/molecules23102723.


Design, synthesis, and biological evaluation of novel pan agonists of FFA1, PPARγ and PPARδ.

Li Z, Zhou Z, Deng F, Li Y, Zhang D, Zhang L.

Eur J Med Chem. 2018 Nov 5;159:267-276. doi: 10.1016/j.ejmech.2018.09.071. Epub 2018 Oct 1.


δ-Tocotrienol, Isolated from Rice Bran, Exerts an Anti-Inflammatory Effect via MAPKs and PPARs Signaling Pathways in Lipopolysaccharide-Stimulated Macrophages.

Shen J, Yang T, Xu Y, Luo Y, Zhong X, Shi L, Hu T, Guo T, Nie Y, Luo F, Lin Q.

Int J Mol Sci. 2018 Oct 4;19(10). pii: E3022. doi: 10.3390/ijms19103022.


Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).

Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA.

ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. doi: 10.1021/acsmedchemlett.8b00287. eCollection 2018 Sep 13.


Peroxisome Proliferator-Activated Receptor-δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4+ T Cells.

Zhao FL, Ahn JJ, Chen ELY, Yi TJ, Stickle NH, Spaner D, Zúñiga-Pflücker JC, Dunn SE.

J Immunol. 2018 Nov 1;201(9):2664-2682. doi: 10.4049/jimmunol.1800374. Epub 2018 Sep 26.


The influence of experimentally induced endometritis on the PPAR expression profile in the bovine endometrium.

Socha BM, Łada P, Szczepańska AA, Łupicka M, Korzekwa AJ.

Theriogenology. 2018 Dec;122:74-83. doi: 10.1016/j.theriogenology.2018.09.013. Epub 2018 Sep 15.


The Role of PPARβ/δ in Melanoma Metastasis.

Lim JCW, Kwan YP, Tan MS, Teo MHY, Chiba S, Wahli W, Wang X.

Int J Mol Sci. 2018 Sep 20;19(10). pii: E2860. doi: 10.3390/ijms19102860.


15d-PGJ2-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice.

Ruiz-Miyazawa KW, Staurengo-Ferrari L, Pinho-Ribeiro FA, Fattori V, Zaninelli TH, Badaro-Garcia S, Borghi SM, Andrade KC, Clemente-Napimoga JT, Alves-Filho JC, Cunha TM, Fraceto LF, Cunha FQ, Napimoga MH, Casagrande R, Verri WA Jr.

Sci Rep. 2018 Sep 18;8(1):13979. doi: 10.1038/s41598-018-32334-0.


Fibroblast growth factor 21 regulates glucose metabolism in part by reducing renal glucose reabsorption.

Li S, Wang N, Guo X, Li J, Zhang T, Ren G, Li D.

Biomed Pharmacother. 2018 Dec;108:355-366. doi: 10.1016/j.biopha.2018.09.078. Epub 2018 Sep 15.

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