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Items: 1 to 20 of 104


Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42.

Razidlo GL, Burton KM, McNiven MA.

J Biol Chem. 2018 Jul 13;293(28):11143-11153. doi: 10.1074/jbc.RA118.003276. Epub 2018 May 31.


Fasting Inhibits the Recruitment of Kinesin-1 to Lipid Droplets and Stalls Hepatic Triglyceride Secretion.

Schulze RJ, McNiven MA.

Hepatology. 2018 May 23. doi: 10.1002/hep.30104. [Epub ahead of print] No abstract available.


Ethanol exposure inhibits hepatocyte lipophagy by inactivating the small guanosine triphosphatase Rab7.

Schulze RJ, Rasineni K, Weller SG, Schott MB, Schroeder B, Casey CA, McNiven MA.

Hepatol Commun. 2017 Mar 10;1(2):140-152. doi: 10.1002/hep4.1021. eCollection 2017 Apr.


Cellular Membrane Trafficking Machineries Used by the Hepatitis Viruses.

Inoue J, Ninomiya M, Shimosegawa T, McNiven MA.

Hepatology. 2018 Aug;68(2):751-762. doi: 10.1002/hep.29785. Review.


Ethanol-induced steatosis involves impairment of lipophagy, associated with reduced Dynamin2 activity.

Rasineni K, Donohue TM Jr, Thomes PG, Yang L, Tuma DJ, McNiven MA, Casey CA.

Hepatol Commun. 2017 Aug;1(6):501-512. doi: 10.1002/hep4.1063. Epub 2017 Jul 10.


Hepatic Lipophagy: New Insights into Autophagic Catabolism of Lipid Droplets in the Liver.

Schulze RJ, Drižytė K, Casey CA, McNiven MA.

Hepatol Commun. 2017 Jul;1(5):359-369. doi: 10.1002/hep4.1056. Epub 2017 Jun 9.


Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase.

Martin C, Leyton L, Hott M, Arancibia Y, Spichiger C, McNiven MA, Court FA, Concha MI, Burgos PV, Otth C.

Front Cell Infect Microbiol. 2017 Aug 22;7:371. doi: 10.3389/fcimb.2017.00371. eCollection 2017.


LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.

Zhu S, Zhang X, Weichert-Leahey N, Dong Z, Zhang C, Lopez G, Tao T, He S, Wood AC, Oldridge D, Ung CY, van Ree JH, Khan A, Salazar BM, Lummertz da Rocha E, Zimmerman MW, Guo F, Cao H, Hou X, Weroha SJ, Perez-Atayde AR, Neuberg DS, Meves A, McNiven MA, van Deursen JM, Li H, Maris JM, Look AT.

Cancer Cell. 2017 Sep 11;32(3):310-323.e5. doi: 10.1016/j.ccell.2017.08.002. Epub 2017 Aug 31.


β-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure.

Schott MB, Rasineni K, Weller SG, Schulze RJ, Sletten AC, Casey CA, McNiven MA.

J Biol Chem. 2017 Jul 14;292(28):11815-11828. doi: 10.1074/jbc.M117.777748. Epub 2017 May 17.


A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets.

Li Z, Schulze RJ, Weller SG, Krueger EW, Schott MB, Zhang X, Casey CA, Liu J, Stöckli J, James DE, McNiven MA.

Sci Adv. 2016 Dec 16;2(12):e1601470. doi: 10.1126/sciadv.1601470. eCollection 2016 Dec.


Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma.

Boddicker RL, Razidlo GL, Dasari S, Zeng Y, Hu G, Knudson RA, Greipp PT, Davila JI, Johnson SH, Porcher JC, Smadbeck JB, Eckloff BW, Billadeau DD, Kurtin PJ, McNiven MA, Link BK, Ansell SM, Cerhan JR, Asmann YW, Vasmatzis G, Feldman AL.

Blood. 2016 Sep 1;128(9):1234-45. doi: 10.1182/blood-2016-03-707141. Epub 2016 Jun 13.


The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase.

Cao H, Schroeder B, Chen J, Schott MB, McNiven MA.

J Biol Chem. 2016 Aug 5;291(32):16424-37. doi: 10.1074/jbc.M116.724997. Epub 2016 May 24.


Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology.

Rasineni K, Penrice DD, Natarajan SK, McNiven MA, McVicker BL, Kharbanda KK, Casey CA, Harris EN.

BMC Gastroenterol. 2016 Feb 29;16:27. doi: 10.1186/s12876-016-0433-4.


Structure, Function and Metabolism of Hepatic and Adipose Tissue Lipid Droplets: Implications in Alcoholic Liver Disease.

Natarajan SK, Rasineni K, Ganesan M, Feng D, McVicker BL, McNiven MA, Osna NA, Mott JL, Casey CA, Kharbanda KK.

Curr Mol Pharmacol. 2017;10(3):237-248. doi: 10.2174/1874467208666150817111727.


Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells.

McGee-Lawrence ME, Carpio LR, Schulze RJ, Pierce JL, McNiven MA, Farr JN, Khosla S, Oursler MJ, Westendorf JJ.

J Bone Miner Res. 2016 Jan;31(1):116-28. doi: 10.1002/jbmr.2602. Epub 2015 Aug 20.


Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process.

Cao H, Eppinga RD, Razidlo GL, Krueger EW, Chen J, Qiang L, McNiven MA.

Oncogene. 2016 Mar 3;35(9):1099-1110. doi: 10.1038/onc.2015.163. Epub 2015 May 18.


Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion.

Razidlo GL, Magnine C, Sletten AC, Hurley RM, Almada LL, Fernandez-Zapico ME, Ji B, McNiven MA.

Cancer Res. 2015 Jul 15;75(14):2907-15. doi: 10.1158/0008-5472.CAN-14-3103. Epub 2015 May 14.


HBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation.

Inoue J, Krueger EW, Chen J, Cao H, Ninomiya M, McNiven MA.

J Cell Sci. 2015 May 1;128(9):1696-706. doi: 10.1242/jcs.158097. Epub 2015 Mar 13.


The small GTPase Rab7 as a central regulator of hepatocellular lipophagy.

Schroeder B, Schulze RJ, Weller SG, Sletten AC, Casey CA, McNiven MA.

Hepatology. 2015 Jun;61(6):1896-907. doi: 10.1002/hep.27667. Epub 2015 Apr 23.


Importance of endocytic pathways in liver function and disease.

Schroeder B, McNiven MA.

Compr Physiol. 2014 Oct;4(4):1403-17. doi: 10.1002/cphy.c140001. Review.

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