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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W, Chi H.

Immunity. 2018 Nov 6. pii: S1074-7613(18)30475-8. doi: 10.1016/j.immuni.2018.10.010. [Epub ahead of print]


First measurements of a scintillator based fast-ion loss detector near the ASDEX Upgrade divertor.

Gonzalez-Martin J, Ayllon-Guerola J, Garcia-Munoz M, Herrmann A, Leitenstern P, De Marne P, Zoletnik S, Kovacsik A, Galdon-Quiroga J, Rivero-Rodriguez J, Rodriguez-Ramos M, Sanchis-Sanchez L, Dominguez J; ASDEX Upgrade Team; MST1 Team.

Rev Sci Instrum. 2018 Oct;89(10):10I106. doi: 10.1063/1.5038968.


High resolution gamma-ray spectrometer with MHz capabilities for runaway electron studies at ASDEX Upgrade.

Nocente M, Shevelev A, Giacomelli L, Pautasso G, Tardocchi M, Gin D, Gobbin M, Gorini G, Fernandes A, Herrmann A, Khilkevitch E, Panontin E, Papp G, Pereira RC, Salewski M, Tardini G, Valisa M; ASDEX Upgrade Team; EUROfusion MST1 Team.

Rev Sci Instrum. 2018 Oct;89(10):10I124. doi: 10.1063/1.5036658.


Observations of core ion cyclotron emission on ASDEX Upgrade tokamak.

Ochoukov R, Bobkov V, Chapman B, Dendy R, Dunne M, Faugel H, García-Muñoz M, Geiger B, Hennequin P, McClements KG, Moseev D, Nielsen S, Rasmussen J, Schneider P, Weiland M, Noterdaeme JM; ASDEX Upgrade Team; EUROfusion MST1 Team.

Rev Sci Instrum. 2018 Oct;89(10):10J101. doi: 10.1063/1.5035180.


Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay.

Karchugina S, Chernoff J.

J Vis Exp. 2018 Oct 20;(140). doi: 10.3791/57755.


Hepatocyte Growth Factor Activator: A Proteinase Linking Tissue Injury with Repair.

Fukushima T, Uchiyama S, Tanaka H, Kataoka H.

Int J Mol Sci. 2018 Nov 1;19(11). pii: E3435. doi: 10.3390/ijms19113435. Review.


Galectin-3 deficiency ameliorates fibrosis and remodelling in dilated cardiomyopathy mice with enhanced Mst1 signaling.

Nguyen MN, Ziemann M, Kiriazis H, Su Y, Donner DG, Zhao WB, Lu Q, Rafehi H, Sadoshima J, McMullen JR, El-Osta A, Du XJ.

Am J Physiol Heart Circ Physiol. 2018 Nov 2. doi: 10.1152/ajpheart.00609.2018. [Epub ahead of print]


The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development.

Alsufyani F, Mattoo H, Zhou D, Cariappa A, Van Buren D, Hock H, Avruch J, Pillai S.

Front Immunol. 2018 Oct 17;9:2393. doi: 10.3389/fimmu.2018.02393. eCollection 2018.


Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation.

Deng Y, Lu J, Li W, Wu A, Zhang X, Tong W, Ho KK, Qin L, Song H, Mak KK.

Nat Commun. 2018 Nov 1;9(1):4564. doi: 10.1038/s41467-018-07022-2.


Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway.

Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, Meng P, Li J.

Redox Biol. 2018 Oct 19;20:261-274. doi: 10.1016/j.redox.2018.10.012. [Epub ahead of print]


Macrophage Stimulating Protein (MSP) Preserves Blood Brain Barrier Integrity After Intracerebral Hemorrhage Through RON Dependent GAB1/Src/β-catenin Pathway Activation in a Mouse Model.

Lu T, Wang Z, Prativa S, Xu Y, Wang T, Zhang Y, Yu L, Xu N, Tang J, You W, Chen G, Zhang JH.

J Neurochem. 2018 Oct 31. doi: 10.1111/jnc.14622. [Epub ahead of print]


Tanshinone IIA promotes IL2-mediated SW480 colorectal cancer cell apoptosis by triggering INF2-related mitochondrial fission and activating the Mst1-Hippo pathway.

Qian J, Fang D, Lu H, Cao Y, Zhang J, Ding R, Li L, Huo J.

Biomed Pharmacother. 2018 Oct 11;108:1658-1669. doi: 10.1016/j.biopha.2018.09.170. [Epub ahead of print]


FFAR1-and FFAR4-dependent activation of Hippo pathway mediates DHA-induced apoptosis of androgen-independent prostate cancer cells.

Wang J, Hong Y, Shao S, Zhang K, Hong W.

Biochem Biophys Res Commun. 2018 Oct 23. pii: S0006-291X(18)32244-7. doi: 10.1016/j.bbrc.2018.10.088. [Epub ahead of print]


The hippo pathway effector YAP promotes epithelial proliferation and remodeling in chronic rhinosinusitis with nasal polyps.

Deng H, Sun Y, Wang W, Li M, Yuan T, Kong W, Huang X, Long Z, Chen Z, Wang D, Yang Q.

Allergy. 2018 Oct 26. doi: 10.1111/all.13647. [Epub ahead of print]


Liraglutide protects against glucolipotoxicity-induced RIN-m5F β-cell apoptosis through restoration of PDX1 expression.

Kornelius E, Li HH, Peng CH, Yang YS, Chen WJ, Chang YZ, Bai YC, Liu S, Huang CN, Lin CL.

J Cell Mol Med. 2018 Oct 24. doi: 10.1111/jcmm.13967. [Epub ahead of print]


Cardiac-specific Mst1 deficiency inhibits ROS-mediated JNK signalling to alleviate Ang II-induced cardiomyocyte apoptosis.

Cheng Z, Zhang M, Hu J, Lin J, Feng X, Wang S, Wang T, Gao E, Wang H, Sun D.

J Cell Mol Med. 2018 Oct 19. doi: 10.1111/jcmm.13958. [Epub ahead of print]


Structural characterization and RAW264.7 murine macrophage stimulating activity of a fucogalactoglucan from Colpomenia peregrina.

Rostami Z, Tabarsa M, You S, Rezaei M.

J Food Sci Technol. 2018 Nov;55(11):4650-4660. doi: 10.1007/s13197-018-3406-5. Epub 2018 Sep 12.


Mst1 regulates non-small cell lung cancer A549 cell apoptosis by inducing mitochondrial damage via ROCK1/F‑actin pathways.

Zhang W, Liu K, Pei Y, Ma J, Tan J, Zhao J.

Int J Oncol. 2018 Oct 8. doi: 10.3892/ijo.2018.4586. [Epub ahead of print]


Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation.

Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, Zhou X, Pfeifer GP, Liu L.

Cell Death Differ. 2018 Oct 12. doi: 10.1038/s41418-018-0211-7. [Epub ahead of print]


Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.

Mana-Capelli S, McCollum D.

J Biol Chem. 2018 Sep 28. pii: jbc.RA118.004187. doi: 10.1074/jbc.RA118.004187. [Epub ahead of print]

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