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Items: 1 to 20 of 227

1.

The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.

Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S.

Mol Cell. 2018 Dec 27. pii: S1097-2765(18)30988-2. doi: 10.1016/j.molcel.2018.11.018. [Epub ahead of print]

2.

The Immunity-related GTPase M rs13361189 variant does not increase the risk for prevalent or incident steatosis; results from the Framingham Heart Study.

Simon TG, Deng X, Liu CT, Chung RT, Long MT.

Liver Int. 2018 Dec 29. doi: 10.1111/liv.14039. [Epub ahead of print]

PMID:
30597691
3.

Impact of Autophagy of Innate Immune Cells on Inflammatory Bowel Disease.

Iida T, Yokoyama Y, Wagatsuma K, Hirayama D, Nakase H.

Cells. 2018 Dec 22;8(1). pii: E7. doi: 10.3390/cells8010007. Review.

4.

Genetic associations of inflammatory bowel disease in a South Asian population.

Niriella MA, Liyanage IK, Kodisinghe SK, Silva AP, Rajapakshe N, Nanayakkara SD, Luke D, Silva T, Nawarathne M, Peiris RK, Kalubovila UP, Kumarasena SR, Dissanayake VHW, Jayasekara RW, de Silva HJ.

World J Clin Cases. 2018 Dec 6;6(15):908-915. doi: 10.12998/wjcc.v6.i15.908.

5.

High expression of immunity-related GTPase family M protein in glioma promotes cell proliferation and autophagy protein expression.

Xu Y, Liu R, Liao C, Liu J, Zhao H, Li Z, Liu W, Chen L, Wu C, Tan H, Chen Z, Xie N, Li W.

Pathol Res Pract. 2019 Jan;215(1):90-96. doi: 10.1016/j.prp.2018.10.004. Epub 2018 Oct 24.

PMID:
30391210
6.

Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.

Ajayi TA, Innes CL, Grimm SA, Rai P, Finethy R, Coers J, Wang X, Bell DA, McGrath JA, Schurman SH, Fessler MB.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G95-G105. doi: 10.1152/ajpgi.00196.2018. Epub 2018 Oct 18.

PMID:
30335469
7.

Live Mycobacterium leprae inhibits autophagy and apoptosis of infected macrophages and prevents engulfment of host cell by phagocytes.

Ma Y, Pei Q, Zhang L, Lu J, Shui T, Chen J, Shi C, Yang J, Smith M, Liu Y, Zhu J, Yang D.

Am J Transl Res. 2018 Sep 15;10(9):2929-2939. eCollection 2018.

8.

Prevalence of Yersinia Species in the Ileum of Crohn's Disease Patients and Controls.

Le Baut G, O'Brien C, Pavli P, Roy M, Seksik P, Tréton X, Nancey S, Barnich N, Bezault M, Auzolle C, Cazals-Hatem D, Viala J, Allez M; REMIND GROUP, Hugot JP, Dumay A.

Front Cell Infect Microbiol. 2018 Sep 21;8:336. doi: 10.3389/fcimb.2018.00336. eCollection 2018.

9.

IRGM promotes glioma M2 macrophage polarization through p62/TRAF6/NF-κB pathway mediated IL-8 production.

Xu Y, Liao C, Liu R, Liu J, Chen Z, Zhao H, Li Z, Chen L, Wu C, Tan H, Liu W, Li W.

Cell Biol Int. 2018 Oct 4. doi: 10.1002/cbin.11061. [Epub ahead of print]

PMID:
30288851
10.

Autophagic Gene Polymorphisms in Liquid Biopsies and Outcome of Patients with Metastatic Clear Cell Renal Cell Carcinoma.

Santoni M, Piva F, De Giorgi U, Mosca A, Basso U, Santini D, Buti S, Lolli C, Terrone C, Maruzzo M, Iuliani M, Bersanelli M, Conti A, Mazzucchelli R, Montironi R, Burattini L, Berardi R.

Anticancer Res. 2018 Oct;38(10):5773-5782. doi: 10.21873/anticanres.12916.

PMID:
30275199
11.

The Role of Autophagy and Related MicroRNAs in Inflammatory Bowel Disease.

Wang S, Huang Y, Zhou C, Wu H, Zhao J, Wu L, Zhao M, Zhang F, Liu H.

Gastroenterol Res Pract. 2018 Jun 4;2018:7565076. doi: 10.1155/2018/7565076. eCollection 2018. Review.

12.

Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases.

Yao QM, Zhu YF, Wang W, Song ZY, Shao XQ, Li L, Song RH, An XF, Qin Q, Li Q, Zhang JA.

Biomed Res Int. 2018 Jun 11;2018:7959707. doi: 10.1155/2018/7959707. eCollection 2018.

13.

Among autophagy genes, ATG16L1 but not IRGM is associated with Crohn's disease in Iranians.

Teimoori-Toolabi L, Samadpoor S, Mehrtash A, Ghadir M, Vahedi H.

Gene. 2018 Oct 30;675:176-184. doi: 10.1016/j.gene.2018.06.074. Epub 2018 Jun 28.

PMID:
29960072
14.

The microbiome of translocated bacterial populations in patients with and without inflammatory bowel disease.

Kiely CJ, Pavli P, O'Brien CL.

Intern Med J. 2018 Nov;48(11):1346-1354. doi: 10.1111/imj.13998.

PMID:
29893034
15.

IRGM Gene Variants Modify the Relationship Between Visceral Adipose Tissue and NAFLD in Patients With Crohn's Disease.

Simon TG, Van Der Sloot KWJ, Chin SB, Joshi AD, Lochhead P, Ananthakrishnan AN, Xavier R, Chung RT, Khalili H.

Inflamm Bowel Dis. 2018 Sep 15;24(10):2247-2257. doi: 10.1093/ibd/izy128.

PMID:
29788077
16.

Regional geochemical baseline concentration of potentially toxic trace metals in the mineralized Lom Basin, East Cameroon: a tool for contamination assessment.

Mimba ME, Ohba T, Nguemhe Fils SC, Nforba MT, Numanami N, Bafon TG, Aka FT, Suh CE.

Geochem Trans. 2018 May 2;19(1):11. doi: 10.1186/s12932-018-0056-5.

17.

Damage-regulated autophagy modulator 1 in oral inflammation and infection.

Memmert S, Nogueira AVB, Damanaki A, Nokhbehsaim M, Eick S, Divnic-Resnik T, Spahr A, Rath-Deschner B, Till A, Götz W, Cirelli JA, Jäger A, Deschner J.

Clin Oral Investig. 2018 Nov;22(8):2933-2941. doi: 10.1007/s00784-018-2381-6. Epub 2018 Feb 13.

PMID:
29442188
18.

Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn's disease.

Gathungu G, Zhang Y, Tian X, Bonkowski E, Rowehl L, Krumsiek J, Nix B, Chalk C, Trapnell B, Zhu W, Newberry R, Denson L, Li E.

World J Gastroenterol. 2018 Feb 7;24(5):623-630. doi: 10.3748/wjg.v24.i5.623.

19.

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi SW, Mudd MH, Claude-Taupin A, Wester MJ, Lidke KA, Rusten TE, Deretic V.

J Cell Biol. 2018 Mar 5;217(3):997-1013. doi: 10.1083/jcb.201708039. Epub 2018 Feb 2.

20.

Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.

Rogala AR, Schoenborn AA, Fee BE, Cantillana VA, Joyce MJ, Gharaibeh RZ, Roy S, Fodor AA, Sartor RB, Taylor GA, Gulati AS.

Dis Model Mech. 2018 Feb 7;11(2). pii: dmm031070. doi: 10.1242/dmm.031070.

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