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Items: 1 to 20 of 498

1.

Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD.

Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R.

Aliment Pharmacol Ther. 2018 Dec 2. doi: 10.1111/apt.15035. [Epub ahead of print]

PMID:
30506692
2.

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.

Ghallab A, Hofmann U, Sezgin S, Vartak N, Hassan R, Zaza A, Godoy P, Schneider KM, Guenther G, Ahmed YA, Abbas AA, Keitel V, Kuepfer L, Dooley S, Lammert F, Trautwein C, Spiteller M, Drasdo D, Hofmann AF, Jansen PLM, Hengstler JG, Reif R.

Hepatology. 2018 Aug 13. doi: 10.1002/hep.30213. [Epub ahead of print]

PMID:
30102412
3.

Absorption of Unconjugated Bile Acids from the Perfused Jejunum of the Anesthetized Rat: Structure-Activity Relationships and Rate-Limiting Steps.

Dupas JL, Ho NFH, Hofmann AF.

Lipids. 2018 May;53(5):465-468. doi: 10.1002/lipd.12052. Epub 2018 Aug 2. No abstract available.

PMID:
30071138
4.

Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease.

Hegyi P, Maléth J, Walters JR, Hofmann AF, Keely SJ.

Physiol Rev. 2018 Oct 1;98(4):1983-2023. doi: 10.1152/physrev.00054.2017.

5.

Bile Acids and the Microbiome in the Cow: Lack of Deoxycholic Acid Hydroxylation.

Hofmann AF, Herdt T, Ames NK, Chen Z, Hagey LR.

Lipids. 2018 Mar;53(3):269-270. doi: 10.1002/lipd.12036. Epub 2018 Apr 18. No abstract available.

PMID:
29668048
6.

Plasma Bile Acid Concentrations in Humans: Suggestions for Presentation in Tabular Form.

Hofmann AF, Marschall HU.

Hepatology. 2018 Aug;68(2):787. doi: 10.1002/hep.29909. No abstract available.

PMID:
29604219
7.

Chemical Synthesis of Rare Natural Bile Acids: 11α-Hydroxy Derivatives of Lithocholic and Chenodeoxycholic Acids.

Namegawa K, Iida K, Omura K, Ogawa S, Hofmann AF, Iida T.

Lipids. 2018 Apr;53(4):403-411. doi: 10.1002/lipd.12013. Epub 2018 Mar 9.

PMID:
29520792
8.

Bile Acid Replacement in Bile Acid Synthesis Defects.

Hofmann AF.

J Pediatr Gastroenterol Nutr. 2017 Dec;65(6):e134. doi: 10.1097/MPG.0000000000001709. No abstract available.

PMID:
28800025
9.

Two Inborn Errors of Bile Acid Biosynthesis: The Need for Recognition and Treatment by Primary Bile Acid Replacement.

Hofmann AF.

J Pediatr Gastroenterol Nutr. 2017 Jun;64(6):849-850. doi: 10.1097/MPG.0000000000001579. No abstract available.

PMID:
28333767
10.

Seventy Years of Polyethylene Glycols in Gastroenterology: The Journey of PEG 4000 and 3350 From Nonabsorbable Marker to Colonoscopy Preparation to Osmotic Laxative.

Fordtran JS, Hofmann AF.

Gastroenterology. 2017 Mar;152(4):675-680. doi: 10.1053/j.gastro.2017.01.027. Epub 2017 Jan 29. No abstract available.

PMID:
28147222
11.

Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage.

Edwards JE, LaCerte C, Peyret T, Gosselin NH, Marier JF, Hofmann AF, Shapiro D.

Clin Transl Sci. 2016 Dec;9(6):328-336. doi: 10.1111/cts.12421. Epub 2016 Oct 15.

12.

Chemical Synthesis of Uncommon Natural Bile Acids: The 9α-Hydroxy Derivatives of Chenodeoxycholic and Lithocholic Acids.

Iida T, Namegawa K, Nakane N, Iida K, Hofmann AF, Omura K.

Chem Pharm Bull (Tokyo). 2016 Sep 1;64(9):1397-402. doi: 10.1248/cpb.c16-00247. Epub 2016 Jun 18.

13.

Let the Bile Flow! 1.0.

Hofmann AF.

Hepatology. 2016 Oct;64(4):1387-8. doi: 10.1002/hep.28633. Epub 2016 Jun 11. No abstract available.

PMID:
27178666
14.

Two Major Bile Acids in the Hornbills, (24R,25S)-3α,7α,24-Trihydroxy-5β-cholestan-27-oyl Taurine and Its 12α-Hydroxy Derivative.

Satoh R, Ogata H, Saito T, Zhou B, Omura K, Kurabuchi S, Mitamura K, Ikegawa S, Hagey LR, Hofmann AF, Iida T.

Lipids. 2016 Jun;51(6):757-68. doi: 10.1007/s11745-016-4150-0. Epub 2016 Apr 23.

PMID:
27108034
15.

Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by 11C-Cholylsarcosine PET.

Sørensen M, Munk OL, Ørntoft NW, Frisch K, Andersen KJ, Mortensen FV, Alstrup AK, Ott P, Hofmann AF, Keiding S.

J Nucl Med. 2016 Jun;57(6):961-6. doi: 10.2967/jnumed.115.171579. Epub 2016 Mar 10.

16.

Novel, major 2α- and 2β-hydroxy bile alcohols and bile acids in the bile of Arapaima gigas, a large South American river fish.

Sato née Okihara R, Saito T, Ogata H, Nakane N, Namegawa K, Sekiguchi S, Omura K, Kurabuchi S, Mitamura K, Ikegawa S, Raines J, Hagey LR, Hofmann AF, Iida T.

Steroids. 2016 Mar;107:112-20. doi: 10.1016/j.steroids.2016.01.001. Epub 2016 Jan 6.

PMID:
26768415
17.

Gastrolithiasis in prehensile-tailed porcupines (Coendou prehensilis): nine cases and pathogenesis of stone formation.

Spriggs M, Thompson KA, Barton D, Talley J, Volle K, Stasiak I, Beyea L, Guthrie A, Roda A, Camborata C, Hofmann AF, Hagey LR.

J Zoo Wildl Med. 2014 Dec;45(4):883-91.

PMID:
25632677
18.

Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with Niemann-Pick disease type C and 3β-hydroxysteroid dehydrogenase deficiency.

Maekawa M, Shimada M, Ohno K, Togawa M, Nittono H, Iida T, Hofmann AF, Goto J, Yamaguchi H, Mano N.

Ann Clin Biochem. 2015 Sep;52(Pt 5):576-87. doi: 10.1177/0004563214568871. Epub 2015 Jan 9.

PMID:
25575700
19.

Improved chemical synthesis, X-ray crystallographic analysis, and NMR characterization of (22R)-/(22S)-hydroxy epimers of bile acids.

Omura K, Ohsaki A, Zhou B, Kushida M, Mitsuma T, Kobayashi A, Hagey LR, Hofmann AF, Iida T.

Lipids. 2014 Nov;49(11):1169-80. doi: 10.1007/s11745-014-3955-y. Epub 2014 Oct 16.

PMID:
25319478
20.

Origin of myofibroblasts in the fibrotic liver in mice.

Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3297-305. doi: 10.1073/pnas.1400062111. Epub 2014 Jul 29.

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