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Systemic lidocaine inhibits high-mobility group box 1 messenger ribonucleic acid expression and protein in BALB/c mice after closed fracture musculoskeletal injury.

Sirait RH, Hatta M, Ramli M, Islam AA, Arief SK.

Saudi J Anaesth. 2018 Jul-Sep;12(3):395-398. doi: 10.4103/sja.SJA_685_17.


PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.

Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, Wen Q, Xie Y, Liu J, Kroemer G, Klionsky DJ, Lotze MT, Zeh HJ, Kang R, Tang D.

Dev Cell. 2018 Aug 3. pii: S1534-5807(18)30597-5. doi: 10.1016/j.devcel.2018.07.012. [Epub ahead of print]


Local and systemic levels of cytokines and danger signals in endometriosis-affected women.

Jaeger-Lansky A, Schmidthaler K, Kuessel L, Gstöttner M, Waidhofer-Söllner P, Zlabinger GJ, Wenzl R, Eiwegger T.

J Reprod Immunol. 2018 Jul 25;130:7-10. doi: 10.1016/j.jri.2018.07.006. [Epub ahead of print]


Paeoniflorin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf-2/HO-1/HMGB1/NF-κB pathway.

Heng Y, Mao W, Yong M, Yang G, Su Q, Wang J.

Microb Pathog. 2018 Aug 7. pii: S0882-4010(18)30088-3. doi: 10.1016/j.micpath.2018.08.009. [Epub ahead of print]


Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome.

Selejan SR, Linz D, Tatu AM, Hohl M, Speer T, Ewen S, Mahfoud F, Kindermann I, Zamyatkin O, Kazakov A, Laufs U, Böhm M.

J Mol Cell Cardiol. 2018 Aug 7;122:34-46. doi: 10.1016/j.yjmcc.2018.08.003. [Epub ahead of print]


Skewed Signaling through the Receptor for Advanced Glycation End-Products Alters the Proinflammatory Profile of Tumor-Associated Macrophages.

Rojas A, Araya P, Romero J, Delgado-López F, Gonzalez I, Añazco C, Perez-Castro R.

Cancer Microenviron. 2018 Aug 8. doi: 10.1007/s12307-018-0214-4. [Epub ahead of print] Review.


Saquinavir plus methylprednisolone ameliorates experimental acute lung injury.

Zhang G, Zhang X, Huang H, Ji Y, Li D, Jiang W.

Braz J Med Biol Res. 2018 Aug 6;51(10):e7579. doi: 10.1590/1414-431X20187579.


High-mobility group box 1 protein-mediated necroptosis contributes to dasatinib-induced cardiotoxicity.

Xu Z, Jin Y, Yan H, Gao Z, Xu B, Yang B, He Q, Shi Q, Luo P.

Toxicol Lett. 2018 Aug 4;296:39-47. doi: 10.1016/j.toxlet.2018.08.003. [Epub ahead of print]


Targeting RAGE as a potential therapeutic approach to Duchenne muscular dystrophy.

Sagheddu R, Chiappalupi S, Salvadori L, Riuzzi F, Donato R, Sorci G.

Hum Mol Genet. 2018 Aug 2. doi: 10.1093/hmg/ddy288. [Epub ahead of print]


Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma.

Zhang DY, Zou XJ, Cao CH, Zhang T, Lei L, Qi XL, Liu L, Wu DH.

Theranostics. 2018 Jun 13;8(14):3751-3765. doi: 10.7150/thno.22493. eCollection 2018.


Intermittent high glucose-induced oxidative stress modulates retinal pigmented epithelial cell autophagy and promotes cell survival via increased HMGB1.

Zhang W, Song J, Zhang Y, Ma Y, Yang J, He G, Chen S.

BMC Ophthalmol. 2018 Aug 6;18(1):192. doi: 10.1186/s12886-018-0864-5.


The anticancer peptide RT53 induces immunogenic cell death.

Pasquereau-Kotula E, Habault J, Kroemer G, Poyet JL.

PLoS One. 2018 Aug 6;13(8):e0201220. doi: 10.1371/journal.pone.0201220. eCollection 2018.


Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption.

Johnson L, Almeida-da-Silva CLC, Takiya CM, Figliuolo V, Rocha GM, Weissmüller G, Scharfstein J, Coutinho-Silva R, Ojcius DM.

Biomed J. 2018 Jun;41(3):184-193. doi: 10.1016/ Epub 2018 Jul 2.


HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?

Amato J, Madanayake TW, Iaccarino N, Novellino E, Randazzo A, Hurley LH, Pagano B.

Chem Commun (Camb). 2018 Aug 6. doi: 10.1039/c8cc03614d. [Epub ahead of print]


Combined gemfibrozil (peroxisome proliferator-activated receptor alpha agonist) with reduced steroid dose gives a similar management picture as the full steroid dose in a rat adjuvant-induced arthritis model.

Ashour H, Rashed LA, El-Sebaie MM, Sabry MM, Abdelmohsen MA, Eissa M.

Mod Rheumatol. 2018 Aug 3:1-25. doi: 10.1080/14397595.2018.1508800. [Epub ahead of print]


Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.

Cardoso AL, Fernandes A, Aguilar-Pimentel JA, de Angelis MH, Guedes JR, Brito MA, Ortolano S, Pani G, Athanasopoulou S, Gonos ES, Schosserer M, Grillari J, Peterson P, Tuna BG, Dogan S, Meyer A, van Os R, Trendelenburg AU.

Ageing Res Rev. 2018 Jul 30. pii: S1568-1637(18)30093-X. doi: 10.1016/j.arr.2018.07.004. [Epub ahead of print] Review.


TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells.

Wu K, Zhang H, Fu Y, Zhu Y, Kong L, Chen L, Zhao F, Yu L, Chen X.

Mol Med Rep. 2018 Sep;18(3):3411-3420. doi: 10.3892/mmr.2018.9326. Epub 2018 Jul 26.


Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway.

Huang M, Geng Y, Deng Q, Li R, Shao X, Zhang Z, Xu W, Wu Y, Ma Q.

Int J Oncol. 2018 Oct;53(4):1481-1492. doi: 10.3892/ijo.2018.4502. Epub 2018 Jul 25.


KPT-330, a potent and selective CRM1 inhibitor, exhibits anti-inflammation effects and protection against sepsis.

Wu M, Gui H, Feng Z, Xu H, Li G, Li M, Chen T, Wu Y, Huang J, Bai Z, Li Y, Pan J, Wang J, Zhou H.

Biochem Biophys Res Commun. 2018 Jul 28. pii: S0006-291X(18)31614-0. doi: 10.1016/j.bbrc.2018.07.112. [Epub ahead of print]


Repeated abortion in adulthood induces cognition impairment in aged mice.

Wang L, Zhang Y, Wang H, Li H, Zhao Z, Wang N, He B, Shi C, Zhang S, Wang J.

Sci Rep. 2018 Jul 30;8(1):11396. doi: 10.1038/s41598-018-29827-3.

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