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Items: 1 to 20 of 25

1.

The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis.

Ploton M, Mazuy C, Gheeraert C, Dubois V, Berthier A, Dubois-Chevalier J, Maréchal X, Bantubungi K, Diemer H, Cianférani S, Strub JM, Helleboid-Chapman A, Eeckhoute J, Staels B, Lefebvre P.

J Hepatol. 2018 Jul 5. pii: S0168-8278(18)32175-5. doi: 10.1016/j.jhep.2018.06.022. [Epub ahead of print]

2.

Reduced Immunohistochemical Expression of Hnf1β and FoxA2 in Liver Tissue Can Discriminate Between Biliary Atresia and Other Causes of Neonatal Cholestasis.

Shaalan UF, Ibrahim NL, Ehsan NA, Sultan MM, Naser GM, Abd El-Fatah MO.

Appl Immunohistochem Mol Morphol. 2018 Feb 28. doi: 10.1097/PAI.0000000000000638. [Epub ahead of print]

PMID:
29406331
3.

FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice.

Wang W, Yao LJ, Shen W, Ding K, Shi PM, Chen F, He J, Ding J, Zhang X, Xie WF.

Sci Rep. 2017 Nov 14;7(1):15532. doi: 10.1038/s41598-017-15831-6.

4.

Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site.

Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y.

Biochemistry. 2017 Jul 25;56(29):3745-3753. doi: 10.1021/acs.biochem.7b00211. Epub 2017 Jul 11.

5.

Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver.

Rogler CE, Bebawee R, Matarlo J, Locker J, Pattamanuch N, Gupta S, Rogler LE.

J Histochem Cytochem. 2017 Jan;65(1):33-46. doi: 10.1369/0022155416675153. Epub 2016 Nov 24.

6.

Metformin impairs systemic bile acid homeostasis through regulating SIRT1 protein levels.

Chen Q, Yang X, Zhang H, Kong X, Yao L, Cui X, Zou Y, Fang F, Yang J, Chang Y.

Biochim Biophys Acta. 2017 Jan;1864(1):101-112. doi: 10.1016/j.bbamcr.2016.10.020. Epub 2016 Nov 3.

7.

Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡.

McDaniel K, Meng F, Wu N, Sato K, Venter J, Bernuzzi F, Invernizzi P, Zhou T, Kyritsi K, Wan Y, Huang Q, Onori P, Francis H, Gaudio E, Glaser S, Alpini G.

Hepatology. 2017 Feb;65(2):544-559. doi: 10.1002/hep.28831. Epub 2016 Nov 5.

8.

Glucocorticoid treatment alters systemic bile acid homeostasis by regulating the biosynthesis and transport of bile salts.

Xiao Y, Yan W, Zhou K, Cao Y, Cai W.

Dig Liver Dis. 2016 Jul;48(7):771-9. doi: 10.1016/j.dld.2016.03.022. Epub 2016 Apr 11.

PMID:
27133208
9.

Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient.

Cavalloni G, Peraldo-Neia C, Varamo C, Casorzo L, Dell'Aglio C, Bernabei P, Chiorino G, Aglietta M, Leone F.

Tumour Biol. 2016 Mar;37(3):4041-52. doi: 10.1007/s13277-015-4215-3. Epub 2015 Oct 20.

10.

Deficiency of Capicua disrupts bile acid homeostasis.

Kim E, Park S, Choi N, Lee J, Yoe J, Kim S, Jung HY, Kim KT, Kang H, Fryer JD, Zoghbi HY, Hwang D, Lee Y.

Sci Rep. 2015 Feb 5;5:8272. doi: 10.1038/srep08272.

11.

Dysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling.

Xiao Y, Wang J, Yan W, Zhou Y, Chen Y, Zhou K, Wen J, Wang Y, Cai W.

J Hepatol. 2015 Apr;62(4):889-96. doi: 10.1016/j.jhep.2014.10.033. Epub 2014 Oct 30.

PMID:
25450715
12.

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH.

Dev Biol. 2014 Dec 15;396(2):201-13. doi: 10.1016/j.ydbio.2014.10.002. Epub 2014 Oct 18.

13.

Novel mechanism of transcriptional repression of the human ATP binding cassette transporter A1 gene in hepatic cells by the winged helix/forkhead box transcription factor A2.

Thymiakou E, Kardassis D.

Biochim Biophys Acta. 2014 Jun;1839(6):526-36. doi: 10.1016/j.bbagrm.2014.04.021. Epub 2014 May 5.

PMID:
24807696
14.

Bile acid-induced inflammatory signaling in mice lacking Foxa2 in the liver leads to activation of mTOR and age-onset obesity.

Bochkis IM, Shin S, Kaestner KH.

Mol Metab. 2013 Aug 24;2(4):447-56. doi: 10.1016/j.molmet.2013.08.005. eCollection 2013.

15.

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets.

Cardinale V, Wang Y, Carpino G, Cui CB, Gatto M, Rossi M, Berloco PB, Cantafora A, Wauthier E, Furth ME, Inverardi L, Dominguez-Bendala J, Ricordi C, Gerber D, Gaudio E, Alvaro D, Reid L.

Hepatology. 2011 Dec;54(6):2159-72. doi: 10.1002/hep.24590.

PMID:
21809358
16.

Differential transcriptional characteristics of small and large biliary epithelial cells derived from small and large bile ducts.

Glaser S, Wang M, Ueno Y, Venter J, Wang K, Chen H, Alpini G, Holterman A.

Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G769-77. doi: 10.1152/ajpgi.00237.2010. Epub 2010 Jun 24.

17.

Foxa1 and Foxa2 regulate bile duct development in mice.

Strazzabosco M.

J Hepatol. 2010 May;52(5):765-7. doi: 10.1016/j.jhep.2009.12.022. Epub 2010 Feb 18. No abstract available.

18.

Foxa1 and Foxa2 regulate bile duct development in mice.

Li Z, White P, Tuteja G, Rubins N, Sackett S, Kaestner KH.

J Clin Invest. 2009 Jun;119(6):1537-45. doi: 10.1172/JCI38201. Epub 2009 May 11.

19.

Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH.

Physiol Genomics. 2009 Jul 9;38(2):186-95. doi: 10.1152/physiolgenomics.90376.2008. Epub 2009 May 5.

20.

Welcoming Foxa2 in the bile acid entourage.

Moschetta A.

Cell Metab. 2008 Oct;8(4):276-8. doi: 10.1016/j.cmet.2008.09.009.

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