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Items: 1 to 20 of 118

1.

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.

Liu JZ, Almarri MA, Gaffney DJ, Mells GF, Jostins L, Cordell HJ, Ducker SJ, Day DB, Heneghan MA, Neuberger JM, Donaldson PT, Bathgate AJ, Burroughs A, Davies MH, Jones DE, Alexander GJ, Barrett JC, Sandford RN, Anderson CA; UK Primary Biliary Cirrhosis (PBC) Consortium; Wellcome Trust Case Control Consortium 3.

Nat Genet. 2012 Oct;44(10):1137-41. doi: 10.1038/ng.2395. Epub 2012 Sep 9.

2.

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, Day CP, Ruiz-Cabello F, Donaldson PT, Stephens C, Pirmohamed M, Romero-Gomez M, Navarro JM, Fontana RJ, Miller M, Groome M, Bondon-Guitton E, Conforti A, Stricker BH, Carvajal A, Ibanez L, Yue QY, Eichelbaum M, Floratos A, Pe'er I, Daly MJ, Goldstein DB, Dillon JF, Nelson MR, Watkins PB, Daly AK; Spanish DILI Registry; EUDRAGENE; DILIN; DILIGEN; International SAEC.

Gastroenterology. 2011 Jul;141(1):338-47. doi: 10.1053/j.gastro.2011.04.001. Epub 2011 Apr 12.

3.

Electrostatic modifications of the human leukocyte antigen DR P9 peptide-binding pocket in primary sclerosing cholangitis: back to the future with human leukocyte antigen DRĪ².

Donaldson PT.

Hepatology. 2011 Jun;53(6):1798-800. doi: 10.1002/hep.24389. No abstract available. Erratum in: Hepatology. 2011 Sep 2;54(3):1114.

PMID:
21538433
4.

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.

Mells GF, Floyd JA, Morley KI, Cordell HJ, Franklin CS, Shin SY, Heneghan MA, Neuberger JM, Donaldson PT, Day DB, Ducker SJ, Muriithi AW, Wheater EF, Hammond CJ, Dawwas MF; UK PBC Consortium; Wellcome Trust Case Control Consortium 3, Jones DE, Peltonen L, Alexander GJ, Sandford RN, Anderson CA.

Nat Genet. 2011 Mar 13;43(4):329-32. doi: 10.1038/ng.789. Erratum in: Nat Genet. 2011 Nov;43(11):1164. Richardson,Paul [added]; Nasr, Ikram [added]; Aspinall,Richard [added].

5.

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury.

Donaldson PT, Daly AK, Henderson J, Graham J, Pirmohamed M, Bernal W, Day CP, Aithal GP.

J Hepatol. 2010 Dec;53(6):1049-53. doi: 10.1016/j.jhep.2010.05.033. Epub 2010 Aug 1.

PMID:
20800921
6.

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP; DILIGEN Study; International SAE Consortium.

Nat Genet. 2009 Jul;41(7):816-9. doi: 10.1038/ng.379. Epub 2009 May 31.

PMID:
19483685
7.

Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

Sutherland A, Davies J, Owen CJ, Vaikkakara S, Walker C, Cheetham TD, James RA, Perros P, Donaldson PT, Cordell HJ, Quinton R, Pearce SH.

J Clin Endocrinol Metab. 2007 Aug;92(8):3338-41. Epub 2007 May 29.

PMID:
17535987
9.

HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: a large-scale study.

Donaldson PT, Baragiotta A, Heneghan MA, Floreani A, Venturi C, Underhill JA, Jones DE, James OF, Bassendine MF.

Hepatology. 2006 Sep;44(3):667-74.

PMID:
16941709
10.

Apolipoprotein epsilon3 allele is associated with persistent hepatitis C virus infection.

Price DA, Bassendine MF, Norris SM, Golding C, Toms GL, Schmid ML, Morris CM, Burt AD, Donaldson PT.

Gut. 2006 May;55(5):715-8. Epub 2005 Nov 18.

11.

Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease.

Todhunter CE, Sutherland-Craggs A, Bartram SA, Donaldson PT, Daly AK, Francis RM, Mansfield JC, Thompson NP.

Gut. 2005 Nov;54(11):1579-84. Epub 2005 Jul 11.

12.

Chemokine receptor 5 and primary biliary cirrhosis: a two-centre genetic association study.

Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones DE, Donaldson PT, Bassendine MF.

Liver Int. 2004 Dec;24(6):646-50.

PMID:
15566517
13.

The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease.

Velaga MR, Wilson V, Jennings CE, Owen CJ, Herington S, Donaldson PT, Ball SG, James RA, Quinton R, Perros P, Pearce SH.

J Clin Endocrinol Metab. 2004 Nov;89(11):5862-5.

PMID:
15531553
14.
15.

Genetics of autoimmune and viral liver diseases; understanding the issues.

Donaldson PT.

J Hepatol. 2004 Aug;41(2):327-32. Review. No abstract available.

PMID:
15288484
16.

Frequency and nature of cytokine gene polymorphisms in hepatocellular carcinoma in Hong Kong Chinese.

Heneghan MA, Johnson PJ, Clare M, Ho S, Harrison PM, Donaldson PT.

Int J Gastrointest Cancer. 2003;34(1):19-26.

PMID:
15235132
17.

Frequency and significance of antibodies to Saccharomyces cerevisiae in autoimmune hepatitis.

Czaja AJ, Shums Z, Donaldson PT, Norman GL.

Dig Dis Sci. 2004 Apr;49(4):611-8.

PMID:
15185865
18.

Cytokine gene polymorphism and immunoregulation in periodontal disease.

Taylor JJ, Preshaw PM, Donaldson PT.

Periodontol 2000. 2004;35:158-82. Review. No abstract available.

PMID:
15107062
19.
20.

Genetic factors in the pathogenesis of primary biliary cirrhosis.

Jones DE, Donaldson PT.

Clin Liver Dis. 2003 Nov;7(4):841-64. Review.

PMID:
14594133

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