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Items: 1 to 20 of 812

1.

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.

Weigand KM, Schirris TJJ, Houweling M, van den Heuvel JJMW, Koenderink JB, Dankers ACA, Russel FGM, Greupink R.

Toxicol In Vitro. 2019 Jan 8. pii: S0887-2333(19)30019-0. doi: 10.1016/j.tiv.2019.01.003. [Epub ahead of print]

PMID:
30639138
2.

A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes vs. Human Liver Tissue Using Quantitative Targeted Proteomics and Cell-Surface Biotinylation.

Kumar V, Salphati L, Hop CECA, Xiao G, Lai Y, Mathias A, Chu X, Humphreys WG, Liao M, Heyward S, Unadkat JD.

Drug Metab Dispos. 2019 Jan 8. pii: dmd.118.084988. doi: 10.1124/dmd.118.084988. [Epub ahead of print]

PMID:
30622164
3.

Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis.

Kim KH, Choi JM, Li F, Dong B, Wooton-Kee CR, Arizpe A, Anakk S, Jung SY, Hartig SM, Moore DD.

Hepatol Commun. 2018 Dec 4;3(1):147-159. doi: 10.1002/hep4.1274. eCollection 2019 Jan.

4.

Association between bile salt export pump polymorphisms and intrahepatic cholestasis of pregnancy susceptibility: a meta-analysis of case-control studies.

Zhou J, Yao Y, Huang X, Chen D, Zhang T, Zhang Y.

Gynecol Endocrinol. 2019 Jan 6:1-5. doi: 10.1080/09513590.2018.1512570. [Epub ahead of print]

PMID:
30614300
5.

Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.

Ali I, Khalid S, Stieger B, Brouwer KLR.

Mol Pharm. 2019 Jan 4. doi: 10.1021/acs.molpharmaceut.8b01124. [Epub ahead of print]

PMID:
30608704
6.

Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-glucuronide and 4-Methylesculetin-7-O-glucuronide.

Li Y, Song W, Ou X, Luo G, Xie Y, Sun R, Wang Y, Qi X, Hu M, Liu Z, Zhu L.

Drug Metab Dispos. 2019 Jan 2. pii: dmd.118.083493. doi: 10.1124/dmd.118.083493. [Epub ahead of print]

PMID:
30602435
7.

Hepatotoxicity induced by psoralen and isopsoralen from Fructus Psoraleae: Wistar rats are more vulnerable than ICR mice.

Wang Y, Zhang H, Jiang JM, Zheng D, Chen YY, Wan SJ, Tan HS, Tang LM, Xu HX.

Food Chem Toxicol. 2018 Dec 28;125:133-140. doi: 10.1016/j.fct.2018.12.047. [Epub ahead of print]

PMID:
30597224
8.

Evidence of functional bile acid signaling pathways in adipocytes.

Schmid A, Schlegel J, Thomalla M, Karrasch T, Schäffler A.

Mol Cell Endocrinol. 2018 Dec 10. pii: S0303-7207(18)30359-9. doi: 10.1016/j.mce.2018.12.006. [Epub ahead of print]

PMID:
30543876
9.

Heme oxygenase-1 induction by hemin prevents oxidative stress-induced acute cholestasis in the rat.

Martín PL, Ceccatto P, Razori MV, Francés DEA, Arriaga SMM, Pisani GB, Martínez AI, Sánchez Pozzi EJ, Roma MG, Basiglio CL.

Clin Sci (Lond). 2019 Jan 11;133(1):117-134. doi: 10.1042/CS20180675. Print 2019 Jan 15.

PMID:
30538149
10.

Polygonum multiflorum Thunb suppress bile acid synthesis by activating Fxr-Fgf15 signaling in the intestine.

Wei J, Chen J, Fu L, Han L, Gao X, Sarhene M, Hu L, Zhang Y, Fan G.

J Ethnopharmacol. 2018 Dec 6. pii: S0378-8741(18)33309-9. doi: 10.1016/j.jep.2018.12.007. [Epub ahead of print]

PMID:
30528660
11.

Hepatic Autophagy Deficiency Compromises FXR Functionality and Causes Cholestatic Injury.

Khambu B, Li T, Yan S, Yu C, Chen X, Goheen M, Li Y, Lin J, Cummings OW, Lee YA, Friedman S, Dong Z, Feng GS, Wu S, Yin XM.

Hepatology. 2018 Dec 5. doi: 10.1002/hep.30407. [Epub ahead of print]

PMID:
30520052
12.

Paradoxical effects of emodin on ANIT-induced intrahepatic cholestasis and herb-induced hepatotoxicity in mice.

Wang X, Han L, Bi Y, Li C, Gao X, Fan G, Zhang Y.

Toxicol Sci. 2018 Dec 4. doi: 10.1093/toxsci/kfy295. [Epub ahead of print]

PMID:
30517764
13.

Overcoming P-glycoprotein mediated drug resistance with noscapine derivatives.

Muthiah D, Henshaw GK, DeBono AJ, Capuano B, Scammells P, Callaghan R.

Drug Metab Dispos. 2018 Nov 26. pii: dmd.118.083188. doi: 10.1124/dmd.118.083188. [Epub ahead of print]

PMID:
30478158
14.

Genetic Variations Associated with Anti-Tuberculosis Drug-Induced Liver Injury.

Bao Y, Ma X, Rasmussen TP, Zhong XB.

Curr Pharmacol Rep. 2018 Jun;4(3):171-181. doi: 10.1007/s40495-018-0131-8. Epub 2018 Mar 15.

15.

Functional analysis of the correlation between ABCB11 gene mutation and primary intrahepatic stone.

Gan L, Pan S, Cui J, Bai J, Jiang P, He Y.

Mol Med Rep. 2018 Nov 15. doi: 10.3892/mmr.2018.9661. [Epub ahead of print]

16.

Effects of Red Ginseng Extract on the Pharmacokinetics and Elimination of Methotrexate via Mrp2 Regulation.

Lee S, Kwon M, Choi MK, Song IS.

Molecules. 2018 Nov 12;23(11). pii: E2948. doi: 10.3390/molecules23112948.

17.

Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.

Wang R, Sheps JA, Liu L, Han J, Chen PSK, Lamontagne J, Wilson PD, Welch I, Borchers CH, Ling V.

J Lipid Res. 2019 Jan;60(1):85-97. doi: 10.1194/jlr.M088070. Epub 2018 Nov 11.

PMID:
30416103
18.

Functional polarization of human hepatoma HepaRG cells in response to forskolin.

Mayati A, Moreau A, Le Vée M, Bruyère A, Jouan E, Denizot C, Parmentier Y, Fardel O.

Sci Rep. 2018 Oct 31;8(1):16115. doi: 10.1038/s41598-018-34421-8.

19.

Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases.

Chen HL, Wu SH, Hsu SH, Liou BY, Chen HL, Chang MH.

J Biomed Sci. 2018 Oct 26;25(1):75. doi: 10.1186/s12929-018-0475-8. Review.

20.

Physical Response to Pad- and Bag-Based Boxing-Specific Training Modalities.

Finlay MJ, Greig M, McCarthy J, Page RM.

J Strength Cond Res. 2018 Oct 24. doi: 10.1519/JSC.0000000000002928. [Epub ahead of print]

PMID:
30358696

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