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Items: 1 to 20 of 134

1.

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells.

Dastidar S, Ardui S, Singh K, Majumdar D, Nair N, Fu Y, Reyon D, Samara E, Gerli MFM, Klein AF, De Schrijver W, Tipanee J, Seneca S, Tulalamba W, Wang H, Chai YC, In't Veld P, Furling D, Tedesco FS, Vermeesch JR, Joung JK, Chuah MK, VandenDriessche T.

Nucleic Acids Res. 2018 Jun 27. doi: 10.1093/nar/gky548. [Epub ahead of print]

PMID:
29947794
2.

Haemophilia gene therapy: From trailblazer to gamechanger.

Evens H, Chuah MK, VandenDriessche T.

Haemophilia. 2018 May;24 Suppl 6:50-59. doi: 10.1111/hae.13494.

PMID:
29878653
3.

Autogenous transalveolar transplantation of maxillary canines: a systematic review and meta-analysis.

Grisar K, Chaabouni D, Romero LPG, Vandendriessche T, Politis C, Jacobs R.

Eur J Orthod. 2018 May 31. doi: 10.1093/ejo/cjy026. [Epub ahead of print]

PMID:
29860316
4.

A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity.

Chamberlain K, Riyad JM, Garnett T, Kohlbrenner E, Mookerjee A, Elmastour F, Benard L, Chen J, VandenDriessche T, Chuah MK, Marian AJ, Hajjar RJ, Gurha P, Weber T.

Hum Gene Ther. 2018 Aug;29(8):927-937. doi: 10.1089/hum.2017.188. Epub 2018 May 9.

PMID:
29641321
5.

Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9.

Singh K, Evens H, Nair N, Rincón MY, Sarcar S, Samara-Kuko E, Chuah MK, VandenDriessche T.

Mol Ther. 2018 May 2;26(5):1241-1254. doi: 10.1016/j.ymthe.2018.02.023. Epub 2018 Mar 6.

6.

Hyperactive Factor IX Padua: A Game-Changer for Hemophilia Gene Therapy.

VandenDriessche T, Chuah MK.

Mol Ther. 2018 Jan 3;26(1):14-16. doi: 10.1016/j.ymthe.2017.12.007. Epub 2017 Dec 21. No abstract available.

PMID:
29274719
7.

Assessing the landscape of percutaneous coronary chronic total occlusion treatment in Belgium and Luxembourg: the Belgian Working Group on Chronic Total Occlusions (BWGCTO) registry.

Maeremans J, Kayaert P, Bataille Y, Bennett J, Ungureanu C, Haine S, Vandendriessche T, Sonck J, Scott B, Coussement P, Dendooven D, Pereira B, Frambach P, Janssens L, Debruyne P, Van Mieghem C, Barbato E, Cornelis K, Stammen F, De Vroey F, Vercauteren S, Drieghe B, Aminian A, Debrauwere J, Carlier S, Coosemans M, Van Reet B, Vandergoten P, Dens JA; (On behalf of the BWGCTO Investigators).

Acta Cardiol. 2017 Nov 28:1-10. doi: 10.1080/00015385.2017.1408891. [Epub ahead of print]

PMID:
29183248
8.

Preclinical and clinical advances in transposon-based gene therapy.

Tipanee J, Chai YC, VandenDriessche T, Chuah MK.

Biosci Rep. 2017 Dec 5;37(6). pii: BSR20160614. doi: 10.1042/BSR20160614. Print 2017 Dec 22. Review.

9.

Transposons: Moving Forward from Preclinical Studies to Clinical Trials.

Tipanee J, VandenDriessche T, Chuah MK.

Hum Gene Ther. 2017 Nov;28(11):1087-1104. doi: 10.1089/hum.2017.128. Epub 2017 Aug 22. Review.

PMID:
28920716
10.

Comparison of radial access versus femoral access with the use of a vascular closure device for the prevention of vascular complications and mortality after percutaneous coronary intervention.

Téblick A, Vanderbruggen W, Vandendriessche T, Bosmans J, Haine SEF, Miljoen H, Segers V, Wouters K, Vrints C, Claeys MJ.

Acta Cardiol. 2018 Jun;73(3):241-247. doi: 10.1080/00015385.2017.1363947. Epub 2017 Aug 29.

PMID:
28851255
11.

A higher volume of fibrotic tissue on virtual histology prior to coronary stent implantation predisposes to more pronounced neointima proliferation.

Haine S, Wouters K, Miljoen H, Vandendriessche T, Claeys M, Bosmans J, Vrints C.

Acta Cardiol. 2018 Apr;73(2):171-178. doi: 10.1080/00015385.2017.1351258. Epub 2017 Aug 11.

PMID:
28799447
12.

Hemophilia Gene Therapy: Ready for Prime Time?

VandenDriessche T, Chuah MK.

Hum Gene Ther. 2017 Nov;28(11):1013-1023. doi: 10.1089/hum.2017.116. Epub 2017 Aug 3. Review.

PMID:
28793786
13.

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model.

Verhelle A, Nair N, Everaert I, Van Overbeke W, Supply L, Zwaenepoel O, Peleman C, Van Dorpe J, Lahoutte T, Devoogdt N, Derave W, Chuah MK, VandenDriessche T, Gettemans J.

Hum Mol Genet. 2017 Aug 1;26(15):3030. doi: 10.1093/hmg/ddx207. No abstract available.

PMID:
28605435
14.

A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice.

Merlin S, Cannizzo ES, Borroni E, Bruscaggin V, Schinco P, Tulalamba W, Chuah MK, Arruda VR, VandenDriessche T, Prat M, Valente G, Follenzi A.

Mol Ther. 2017 Aug 2;25(8):1815-1830. doi: 10.1016/j.ymthe.2017.04.029. Epub 2017 May 26.

15.

AAV Capsid Engineering: Zooming in on the Target.

VandenDriessche T.

Hum Gene Ther. 2017 May;28(5):373-374. doi: 10.1089/hum.2017.29042.tva. No abstract available.

PMID:
28498776
16.

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model.

Verhelle A, Nair N, Everaert I, Van Overbeke W, Supply L, Zwaenepoel O, Peleman C, Van Dorpe J, Lahoutte T, Devoogdt N, Derave W, Chuah MK, VandenDriessche T, Gettemans J.

Hum Mol Genet. 2017 Apr 1;26(7):1353-1364. doi: 10.1093/hmg/ddx056. Erratum in: Hum Mol Genet. 2017 Aug 1;26(15):3030.

PMID:
28334940
17.

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

Levy C, Fusil F, Amirache F, Costa C, Girard-Gagnepain A, Negre D, Bernadin O, Garaulet G, Rodriguez A, Nair N, Vandendriessche T, Chuah M, Cosset FL, Verhoeyen E.

J Thromb Haemost. 2016 Dec;14(12):2478-2492. doi: 10.1111/jth.13520. Epub 2016 Nov 8.

PMID:
27685947
18.

CRISPR/Cas9 Flexes Its Muscles: In Vivo Somatic Gene Editing for Muscular Dystrophy.

VandenDriessche T, Chuah MK.

Mol Ther. 2016 Mar;24(3):414-6. doi: 10.1038/mt.2016.29. No abstract available.

19.

Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?

Berns KI, Byrne BJ, Flotte TR, Gao G, Hauswirth WW, Herzog RW, Muzyczka N, VandenDriessche T, Xiao X, Zolotukhin S, Srivastava A.

Hum Gene Ther. 2015 Dec;26(12):779-81. doi: 10.1089/hum.2015.29014.kib. No abstract available.

20.

piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts.

Loperfido M, Jarmin S, Dastidar S, Di Matteo M, Perini I, Moore M, Nair N, Samara-Kuko E, Athanasopoulos T, Tedesco FS, Dickson G, Sampaolesi M, VandenDriessche T, Chuah MK.

Nucleic Acids Res. 2016 Jan 29;44(2):744-60. doi: 10.1093/nar/gkv1464. Epub 2015 Dec 17.

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