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Items: 1 to 20 of 28

1.

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration.

Zhang W, Muck-Hausl M, Wang J, Sun C, Gebbing M, Miskey C, Ivics Z, Izsvak Z, Ehrhardt A.

PLoS One. 2020 Feb 4;15(2):e0228902. doi: 10.1371/journal.pone.0228902. eCollection 2020.

2.

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization.

Hernandez M, Recalde S, Garcia-Garcia L, Bezunartea J, Miskey C, Johnen S, Diarra S, Sebe A, Rodriguez-Madoz JR, Pouillot S, Marie C, Izsvák Z, Scherman D, Kropp M, Prosper F, Thumann G, Ivics Z, Garcia-Layana A, Fernandez-Robredo P.

Mol Ther Methods Clin Dev. 2019 Nov 9;15:403-417. doi: 10.1016/j.omtm.2019.10.013. eCollection 2019 Dec 13.

3.

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.

Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z.

Nucleic Acids Res. 2020 Jan 10;48(1):316-331. doi: 10.1093/nar/gkz1119.

4.

A highly soluble Sleeping Beauty transposase improves control of gene insertion.

Querques I, Mades A, Zuliani C, Miskey C, Alb M, Grueso E, Machwirth M, Rausch T, Einsele H, Ivics Z, Hudecek M, Barabas O.

Nat Biotechnol. 2019 Dec;37(12):1502-1512. doi: 10.1038/s41587-019-0291-z. Epub 2019 Nov 4.

PMID:
31685959
5.

Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons allow transcription in distantly related genomes.

Palazzo A, Lorusso P, Miskey C, Walisko O, Gerbino A, Marobbio CMT, Ivics Z, Marsano RM.

Mob DNA. 2019 Apr 3;10:13. doi: 10.1186/s13100-019-0155-6. eCollection 2019.

6.

Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis.

Guan S, Munder A, Hedtfeld S, Braubach P, Glage S, Zhang L, Lienenklaus S, Schultze A, Hasenpusch G, Garrels W, Stanke F, Miskey C, Johler SM, Kumar Y, Tümmler B, Rudolph C, Ivics Z, Rosenecker J.

Nat Nanotechnol. 2019 Mar;14(3):287-297. doi: 10.1038/s41565-018-0358-x. Epub 2019 Jan 28.

PMID:
30692673
7.

Efficient Non-Viral T-Cell Engineering by Sleeping Beauty Minicircles Diminishing DNA Toxicity and miRNAs Silencing the Endogenous T-Cell Receptors.

Clauss J, Obenaus M, Miskey C, Ivics Z, Izsvák Z, Uckert W, Bunse M.

Hum Gene Ther. 2018 May;29(5):569-584. doi: 10.1089/hum.2017.136.

PMID:
29562762
8.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z.

Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31.

9.

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails.

Benleulmi MS, Matysiak J, Robert X, Miskey C, Mauro E, Lapaillerie D, Lesbats P, Chaignepain S, Henriquez DR, Calmels C, Oladosu O, Thierry E, Leon O, Lavigne M, Andreola ML, Delelis O, Ivics Z, Ruff M, Gouet P, Parissi V.

Retrovirology. 2017 Nov 28;14(1):54. doi: 10.1186/s12977-017-0378-x.

10.

Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids.

Thumann G, Harmening N, Prat-Souteyrand C, Marie C, Pastor M, Sebe A, Miskey C, Hurst LD, Diarra S, Kropp M, Walter P, Scherman D, Ivics Z, Izsvák Z, Johnen S.

Mol Ther Nucleic Acids. 2017 Mar 17;6:302-314. doi: 10.1016/j.omtn.2017.02.002. Epub 2017 Feb 10.

11.

Transposition of the bamboo Mariner-like element Ppmar1 in yeast.

Zhou MB, Hu H, Miskey C, Lazarow K, Ivics Z, Kunze R, Yang G, Izsvák Z, Tang DQ.

Mol Phylogenet Evol. 2017 Apr;109:367-374. doi: 10.1016/j.ympev.2017.02.005. Epub 2017 Feb 9.

PMID:
28189615
12.

Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.

Hudecek M, Gogishvili T, Monjezi R, Wegner J, Shankar R, Kruesemann C, Miskey C, Ivics Z, Schmeer M, Schleef M.

Recent Results Cancer Res. 2016;209:37-50. doi: 10.1007/978-3-319-42934-2_3. Review.

PMID:
28101686
13.

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors.

Monjezi R, Miskey C, Gogishvili T, Schleef M, Schmeer M, Einsele H, Ivics Z, Hudecek M.

Leukemia. 2017 Jan;31(1):186-194. doi: 10.1038/leu.2016.180. Epub 2016 Jun 24.

PMID:
27491640
14.

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.

Grabundzija I, Messing SA, Thomas J, Cosby RL, Bilic I, Miskey C, Gogol-Döring A, Kapitonov V, Diem T, Dalda A, Jurka J, Pritham EJ, Dyda F, Izsvák Z, Ivics Z.

Nat Commun. 2016 Mar 2;7:10716. doi: 10.1038/ncomms10716.

15.

Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells.

Gogol-Döring A, Ammar I, Gupta S, Bunse M, Miskey C, Chen W, Uckert W, Schulz TF, Izsvák Z, Ivics Z.

Mol Ther. 2016 Mar;24(3):592-606. doi: 10.1038/mt.2016.11. Epub 2016 Jan 12.

16.

Integration profile and safety of an adenovirus hybrid-vector utilizing hyperactive sleeping beauty transposase for somatic integration.

Zhang W, Muck-Hausl M, Wang J, Sun C, Gebbing M, Miskey C, Ivics Z, Izsvak Z, Ehrhardt A.

PLoS One. 2013 Oct 4;8(10):e75344. doi: 10.1371/journal.pone.0075344. eCollection 2013. Erratum in: PLoS One. 2014;9(9):e108836. PLoS One. 2020 Feb 4;15(2):e0228902.

17.

Regulation of DNA transposition by CpG methylation and chromatin structure in human cells.

Jursch T, Miskey C, Izsvák Z, Ivics Z.

Mob DNA. 2013 May 15;4(1):15. doi: 10.1186/1759-8753-4-15.

18.

Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element.

Hozumi A, Mita K, Miskey C, Mates L, Izsvak Z, Ivics Z, Satake H, Sasakura Y.

Dev Dyn. 2013 Jan;242(1):30-43. doi: 10.1002/dvdy.23891. Epub 2012 Nov 14.

19.

Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains.

Voigt K, Gogol-Döring A, Miskey C, Chen W, Cathomen T, Izsvák Z, Ivics Z.

Mol Ther. 2012 Oct;20(10):1852-62. doi: 10.1038/mt.2012.126. Epub 2012 Jul 10.

20.

Retargeting transposon insertions by the adeno-associated virus Rep protein.

Ammar I, Gogol-Döring A, Miskey C, Chen W, Cathomen T, Izsvák Z, Ivics Z.

Nucleic Acids Res. 2012 Aug;40(14):6693-712. doi: 10.1093/nar/gks317. Epub 2012 Apr 19.

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