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Items: 1 to 20 of 22

1.

Efficient Non-Viral T-Cell Engineering by Sleeping Beauty Minicircles Diminishing DNA Toxicity and miRNAs Silencing the Endogenous T-Cell Receptors.

Clauss J, Obenaus M, Miskey C, Ivics Z, Izsvák Z, Uckert W, Bunse M.

Hum Gene Ther. 2018 May;29(5):569-584. doi: 10.1089/hum.2017.136.

PMID:
29562762
2.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z.

Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31.

3.

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails.

Benleulmi MS, Matysiak J, Robert X, Miskey C, Mauro E, Lapaillerie D, Lesbats P, Chaignepain S, Henriquez DR, Calmels C, Oladosu O, Thierry E, Leon O, Lavigne M, Andreola ML, Delelis O, Ivics Z, Ruff M, Gouet P, Parissi V.

Retrovirology. 2017 Nov 28;14(1):54. doi: 10.1186/s12977-017-0378-x.

4.

Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids.

Thumann G, Harmening N, Prat-Souteyrand C, Marie C, Pastor M, Sebe A, Miskey C, Hurst LD, Diarra S, Kropp M, Walter P, Scherman D, Ivics Z, Izsvák Z, Johnen S.

Mol Ther Nucleic Acids. 2017 Mar 17;6:302-314. doi: 10.1016/j.omtn.2017.02.002. Epub 2017 Feb 10.

5.

Transposition of the bamboo Mariner-like element Ppmar1 in yeast.

Zhou MB, Hu H, Miskey C, Lazarow K, Ivics Z, Kunze R, Yang G, Izsvák Z, Tang DQ.

Mol Phylogenet Evol. 2017 Apr;109:367-374. doi: 10.1016/j.ympev.2017.02.005. Epub 2017 Feb 9.

PMID:
28189615
6.

Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.

Hudecek M, Gogishvili T, Monjezi R, Wegner J, Shankar R, Kruesemann C, Miskey C, Ivics Z, Schmeer M, Schleef M.

Recent Results Cancer Res. 2016;209:37-50. doi: 10.1007/978-3-319-42934-2_3. Review.

PMID:
28101686
7.

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors.

Monjezi R, Miskey C, Gogishvili T, Schleef M, Schmeer M, Einsele H, Ivics Z, Hudecek M.

Leukemia. 2017 Jan;31(1):186-194. doi: 10.1038/leu.2016.180. Epub 2016 Jun 24.

PMID:
27491640
8.

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.

Grabundzija I, Messing SA, Thomas J, Cosby RL, Bilic I, Miskey C, Gogol-Döring A, Kapitonov V, Diem T, Dalda A, Jurka J, Pritham EJ, Dyda F, Izsvák Z, Ivics Z.

Nat Commun. 2016 Mar 2;7:10716. doi: 10.1038/ncomms10716.

9.

Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells.

Gogol-Döring A, Ammar I, Gupta S, Bunse M, Miskey C, Chen W, Uckert W, Schulz TF, Izsvák Z, Ivics Z.

Mol Ther. 2016 Mar;24(3):592-606. doi: 10.1038/mt.2016.11. Epub 2016 Jan 12.

10.

Integration profile and safety of an adenovirus hybrid-vector utilizing hyperactive sleeping beauty transposase for somatic integration.

Zhang W, Muck-Hausl M, Wang J, Sun C, Gebbing M, Miskey C, Ivics Z, Izsvak Z, Ehrhardt A.

PLoS One. 2013 Oct 4;8(10):e75344. doi: 10.1371/journal.pone.0075344. eCollection 2013. Erratum in: PLoS One. 2014;9(9):e108836.

11.

Regulation of DNA transposition by CpG methylation and chromatin structure in human cells.

Jursch T, Miskey C, Izsvák Z, Ivics Z.

Mob DNA. 2013 May 15;4(1):15. doi: 10.1186/1759-8753-4-15.

12.

Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element.

Hozumi A, Mita K, Miskey C, Mates L, Izsvak Z, Ivics Z, Satake H, Sasakura Y.

Dev Dyn. 2013 Jan;242(1):30-43. doi: 10.1002/dvdy.23891. Epub 2012 Nov 14.

13.

Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains.

Voigt K, Gogol-Döring A, Miskey C, Chen W, Cathomen T, Izsvák Z, Ivics Z.

Mol Ther. 2012 Oct;20(10):1852-62. doi: 10.1038/mt.2012.126. Epub 2012 Jul 10.

14.

Retargeting transposon insertions by the adeno-associated virus Rep protein.

Ammar I, Gogol-Döring A, Miskey C, Chen W, Cathomen T, Izsvák Z, Ivics Z.

Nucleic Acids Res. 2012 Aug;40(14):6693-712. doi: 10.1093/nar/gks317. Epub 2012 Apr 19.

15.

Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells.

Moldt B, Miskey C, Staunstrup NH, Gogol-Döring A, Bak RO, Sharma N, Mátés L, Izsvák Z, Chen W, Ivics Z, Mikkelsen JG.

Mol Ther. 2011 Aug;19(8):1499-510. doi: 10.1038/mt.2011.47. Epub 2011 Apr 5.

16.

Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery.

Orbán TI, Apáti A, Németh A, Varga N, Krizsik V, Schamberger A, Szebényi K, Erdei Z, Várady G, Karászi E, Homolya L, Német K, Gócza E, Miskey C, Mátés L, Ivics Z, Izsvák Z, Sarkadi B.

Stem Cells. 2009 May;27(5):1077-87. doi: 10.1002/stem.45.

17.

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.

Mátés L, Chuah MK, Belay E, Jerchow B, Manoj N, Acosta-Sanchez A, Grzela DP, Schmitt A, Becker K, Matrai J, Ma L, Samara-Kuko E, Gysemans C, Pryputniewicz D, Miskey C, Fletcher B, VandenDriessche T, Ivics Z, Izsvák Z.

Nat Genet. 2009 Jun;41(6):753-61. doi: 10.1038/ng.343. Epub 2009 May 3.

PMID:
19412179
18.

Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators.

Walisko O, Schorn A, Rolfs F, Devaraj A, Miskey C, Izsvák Z, Ivics Z.

Mol Ther. 2008 Feb;16(2):359-69. Epub 2007 Dec 11.

19.

The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends.

Miskey C, Papp B, Mátés L, Sinzelle L, Keller H, Izsvák Z, Ivics Z.

Mol Cell Biol. 2007 Jun;27(12):4589-600. Epub 2007 Apr 2.

20.

DNA transposons in vertebrate functional genomics.

Miskey C, Izsvák Z, Kawakami K, Ivics Z.

Cell Mol Life Sci. 2005 Mar;62(6):629-41. Review.

PMID:
15770416

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