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Items: 19

1.

Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy.

Rincon MY, Sarcar S, Danso-Abeam D, Keyaerts M, Matrai J, Samara-Kuko E, Acosta-Sanchez A, Athanasopoulos T, Dickson G, Lahoutte T, De Bleser P, VandenDriessche T, Chuah MK.

Mol Ther. 2015 Jan;23(1):43-52. doi: 10.1038/mt.2014.178. Epub 2014 Sep 8.

2.

Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.

Chuah MK, Petrus I, De Bleser P, Le Guiner C, Gernoux G, Adjali O, Nair N, Willems J, Evens H, Rincon MY, Matrai J, Di Matteo M, Samara-Kuko E, Yan B, Acosta-Sanchez A, Meliani A, Cherel G, Blouin V, Christophe O, Moullier P, Mingozzi F, VandenDriessche T.

Mol Ther. 2014 Sep;22(9):1605-13. doi: 10.1038/mt.2014.114. Epub 2014 Jun 23.

3.

Understanding the role of defective invertases in plants: tobacco Nin88 fails to degrade sucrose.

Le Roy K, Vergauwen R, Struyf T, Yuan S, Lammens W, Mátrai J, De Maeyer M, Van den Ende W.

Plant Physiol. 2013 Apr;161(4):1670-81. doi: 10.1104/pp.112.209460. Epub 2013 Feb 27.

4.

Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice.

Cantore A, Nair N, Della Valle P, Di Matteo M, Màtrai J, Sanvito F, Brombin C, Di Serio C, D'Angelo A, Chuah M, Naldini L, Vandendriessche T.

Blood. 2012 Nov 29;120(23):4517-20. doi: 10.1182/blood-2012-05-432591. Epub 2012 Oct 4.

5.

PiggyBac toolbox.

Di Matteo M, Mátrai J, Belay E, Firdissa T, Vandendriessche T, Chuah MK.

Methods Mol Biol. 2012;859:241-54. doi: 10.1007/978-1-61779-603-6_14. Review.

PMID:
22367876
6.

Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk.

Mátrai J, Cantore A, Bartholomae CC, Annoni A, Wang W, Acosta-Sanchez A, Samara-Kuko E, De Waele L, Ma L, Genovese P, Damo M, Arens A, Goudy K, Nichols TC, von Kalle C, L Chuah MK, Roncarolo MG, Schmidt M, Vandendriessche T, Naldini L.

Hepatology. 2011 May;53(5):1696-707. doi: 10.1002/hep.24230.

7.

Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation.

Belay E, Mátrai J, Acosta-Sanchez A, Ma L, Quattrocelli M, Mátés L, Sancho-Bru P, Geraerts M, Yan B, Vermeesch J, Rincón MY, Samara-Kuko E, Ivics Z, Verfaillie C, Sampaolesi M, Izsvák Z, Vandendriessche T, Chuah MK.

Stem Cells. 2010 Oct;28(10):1760-71. doi: 10.1002/stem.501.

8.

Preclinical and clinical progress in hemophilia gene therapy.

Mátrai J, Chuah MK, VandenDriessche T.

Curr Opin Hematol. 2010 Sep;17(5):387-92. doi: 10.1097/MOH.0b013e32833cd4bd. Review.

PMID:
20657281
9.

Comparative analysis of transposable element vector systems in human cells.

Grabundzija I, Irgang M, Mátés L, Belay E, Matrai J, Gogol-Döring A, Kawakami K, Chen W, Ruiz P, Chuah MK, VandenDriessche T, Izsvák Z, Ivics Z.

Mol Ther. 2010 Jun;18(6):1200-9. doi: 10.1038/mt.2010.47. Epub 2010 Apr 6.

10.

Recent advances in lentiviral vector development and applications.

Mátrai J, Chuah MK, VandenDriessche T.

Mol Ther. 2010 Mar;18(3):477-90. doi: 10.1038/mt.2009.319. Epub 2010 Jan 19. Review. Erratum in: Mol Ther. 2010 May;18(5):1055.

11.

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.

Mátés L, Chuah MK, Belay E, Jerchow B, Manoj N, Acosta-Sanchez A, Grzela DP, Schmitt A, Becker K, Matrai J, Ma L, Samara-Kuko E, Gysemans C, Pryputniewicz D, Miskey C, Fletcher B, VandenDriessche T, Ivics Z, Izsvák Z.

Nat Genet. 2009 Jun;41(6):753-61. doi: 10.1038/ng.343. Epub 2009 May 3.

PMID:
19412179
12.

Exploration of the activation pathway of Deltaalpha-Chymotrypsin with molecular dynamics simulations and correlation with kinetic experiments.

Mátrai J, Jonckheer A, Joris E, Krüger P, Carpenter E, Tuszynski J, De Maeyer M, Engelborghs Y.

Eur Biophys J. 2008 Nov;38(1):13-23. doi: 10.1007/s00249-008-0348-2. Epub 2008 Aug 27.

PMID:
18751692
13.

An alternate sucrose binding mode in the E203Q Arabidopsis invertase mutant: an X-ray crystallography and docking study.

Mátrai J, Lammens W, Jonckheer A, Le Roy K, Rabijns A, Van den Ende W, De Maeyer M.

Proteins. 2008 May 1;71(2):552-64.

PMID:
17963237
14.

Combined molecular and supramolecular bottom-up nanoengineering for enhanced nonlinear optical response: experiments, modeling, and approaching the fundamental limit.

Pérez-Moreno J, Asselberghs I, Song K, Clays K, Zhao Y, Nakanishi H, Okada S, Nogi K, Kim OK, Je J, Mátrai J, De Maeyer M, Kuzyk MG.

J Chem Phys. 2007 Feb 21;126(7):074705.

PMID:
17328625
15.

Simulation of the activation of alpha-chymotrypsin: analysis of the pathway and role of the propeptide.

Mátrai J, Verheyden G, Krüger P, Engelborghs Y.

Protein Sci. 2004 Dec;13(12):3139-50.

16.

A fluorescence stopped-flow kinetic study of the conformational activation of alpha-chymotrypsin and several mutants.

Verheyden G, Matrai J, Volckaert G, Engelborghs Y.

Protein Sci. 2004 Sep;13(9):2533-40.

17.

Mechanism of the ring-chain rearrangement in phosphiranes: hydrogen versus halogen migration.

Mátrai J, Dransfeld A, Veszprémi T, Nguyen MT.

J Org Chem. 2001 Aug 24;66(17):5671-8.

PMID:
11511238
18.

The clinical use of aluminium oxide bioceramic implants for mandibular condyle replacement: a six year report.

Szabó G, Barabás J, Mátrai J.

J Long Term Eff Med Implants. 1991;1(1):79-88.

PMID:
10171108
19.

Application of compact aluminum oxide ceramic implants in maxillofacial surgery.

Szabó G, Barabás J, Mátrai J, György J, Miklós L.

J Oral Maxillofac Surg. 1990 Apr;48(4):354-61. Review.

PMID:
2179493

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