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Items: 1 to 20 of 146

1.

Corrigendum: Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.

Grandi FC, Rosser JM, Newkirk SJ, Yin J, Jiang X, Xing Z, Whitmore L, Bashir S, Ivics Z, Izsvák Z, Ye P, Yu YE, An W.

Genome Res. 2020 Feb;30(2):313. doi: 10.1101/gr.261677.120. No abstract available.

PMID:
32079650
2.

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration.

Zhang W, Muck-Hausl M, Wang J, Sun C, Gebbing M, Miskey C, Ivics Z, Izsvak Z, Ehrhardt A.

PLoS One. 2020 Feb 4;15(2):e0228902. doi: 10.1371/journal.pone.0228902. eCollection 2020.

3.

Correction: Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells.

Zhang W, Solanki M, Müther N, Ebel M, Wang J, Sun C, Izsvak Z, Ehrhardt A.

PLoS One. 2020 Jan 30;15(1):e0228707. doi: 10.1371/journal.pone.0228707. eCollection 2020.

4.

Correction: Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells.

Turchiano G, Latella MC, Döring AG, Cattoglio C, Mavilio F, Izsvák Z, Ivics Z, Recchia A.

PLoS One. 2020 Jan 30;15(1):e0228703. doi: 10.1371/journal.pone.0228703. eCollection 2020.

5.

Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats.

Liška F, Peterková R, Peterka M, Landa V, Zídek V, Mlejnek P, Šilhavý J, Šimáková M, Křen V, Starker CG, Voytas DF, Izsvák Z, Pravenec M.

PLoS One. 2020 Jan 16;15(1):e0228139. doi: 10.1371/journal.pone.0228139. eCollection 2020.

6.

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization.

Hernandez M, Recalde S, Garcia-Garcia L, Bezunartea J, Miskey C, Johnen S, Diarra S, Sebe A, Rodriguez-Madoz JR, Pouillot S, Marie C, Izsvák Z, Scherman D, Kropp M, Prosper F, Thumann G, Ivics Z, Garcia-Layana A, Fernandez-Robredo P.

Mol Ther Methods Clin Dev. 2019 Nov 9;15:403-417. doi: 10.1016/j.omtm.2019.10.013. eCollection 2019 Dec 13.

7.

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.

Kesselring L, Miskey C, Zuliani C, Querques I, Kapitonov V, Laukó A, Fehér A, Palazzo A, Diem T, Lustig J, Sebe A, Wang Y, Dinnyés A, Izsvák Z, Barabas O, Ivics Z.

Nucleic Acids Res. 2020 Jan 10;48(1):316-331. doi: 10.1093/nar/gkz1119.

8.

Correction: Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells.

Wang Y, Wang J, Devaraj A, Singh M, Jimenez Orgaz A, Chen JX, Selbach M, Ivics Z, Izsvák Z.

PLoS Genet. 2019 Sep 23;15(9):e1008406. doi: 10.1371/journal.pgen.1008406. eCollection 2019 Sep.

9.

Critical role for Piccolo in synaptic vesicle retrieval.

Ackermann F, Schink KO, Bruns C, Izsvák Z, Hamra FK, Rosenmund C, Garner CC.

Elife. 2019 May 10;8. pii: e46629. doi: 10.7554/eLife.46629.

10.

A Multiple Piccolino-RIBEYE Interaction Supports Plate-Shaped Synaptic Ribbons in Retinal Neurons.

Müller TM, Gierke K, Joachimsthaler A, Sticht H, Izsvák Z, Hamra FK, Fejtová A, Ackermann F, Garner CC, Kremers J, Brandstätter JH, Regus-Leidig H.

J Neurosci. 2019 Apr 3;39(14):2606-2619. doi: 10.1523/JNEUROSCI.2038-18.2019. Epub 2019 Jan 29.

11.

Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.

Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG.

Nat Commun. 2018 Dec 19;9(1):5398. doi: 10.1038/s41467-018-07917-0.

12.

Ten things you should know about transposable elements.

Bourque G, Burns KH, Gehring M, Gorbunova V, Seluanov A, Hammell M, Imbeault M, Izsvák Z, Levin HL, Macfarlan TS, Mager DL, Feschotte C.

Genome Biol. 2018 Nov 19;19(1):199. doi: 10.1186/s13059-018-1577-z. Review.

13.

In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.

Wang H, Georgakopoulou A, Psatha N, Li C, Capsali C, Samal HB, Anagnostopoulos A, Ehrhardt A, Izsvák Z, Papayannopoulou T, Yannaki E, Lieber A.

J Clin Invest. 2019 Feb 1;129(2):598-615. doi: 10.1172/JCI122836. Epub 2018 Dec 18.

14.

Author Correction: Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression.

Wang J, Singh M, Sun C, Besser D, Prigione A, Ivics Z, Hurst LD, Izsvák Z.

Nat Protoc. 2019 Aug;14(8):2596. doi: 10.1038/s41596-018-0086-6.

PMID:
30374153
15.

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors.

Fink S, Zugelder L, Roth B, Brandt E, Meloche S, Izsvák Z, Bargou RC, Stühmer T.

PLoS One. 2018 Oct 19;13(10):e0205585. doi: 10.1371/journal.pone.0205585. eCollection 2018.

16.

The Antibiotic-free pFAR4 Vector Paired with the Sleeping Beauty Transposon System Mediates Efficient Transgene Delivery in Human Cells.

Pastor M, Johnen S, Harmening N, Quiviger M, Pailloux J, Kropp M, Walter P, Ivics Z, Izsvák Z, Thumann G, Scherman D, Marie C.

Mol Ther Nucleic Acids. 2018 Jun 1;11:57-67. doi: 10.1016/j.omtn.2017.12.017. Epub 2017 Dec 30.

17.

Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies.

Li C, Psatha N, Wang H, Singh M, Samal HB, Zhang W, Ehrhardt A, Izsvák Z, Papayannopoulou T, Lieber A.

Mol Ther Methods Clin Dev. 2018 Feb 15;9:142-152. doi: 10.1016/j.omtm.2018.02.004. eCollection 2018 Jun 15.

18.

Improved molecular platform for the gene therapy of rare diseases by liver protein secretion.

Quiviger M, Giannakopoulos A, Verhenne S, Marie C, Stavrou EF, Vanhoorelbeke K, Izsvák Z, De Meyer SF, Athanassiadou A, Scherman D.

Eur J Med Genet. 2018 Nov;61(11):723-728. doi: 10.1016/j.ejmg.2018.04.010. Epub 2018 Apr 26. Review.

PMID:
29704684
19.

Efficient Non-Viral T-Cell Engineering by Sleeping Beauty Minicircles Diminishing DNA Toxicity and miRNAs Silencing the Endogenous T-Cell Receptors.

Clauss J, Obenaus M, Miskey C, Ivics Z, Izsvák Z, Uckert W, Bunse M.

Hum Gene Ther. 2018 May;29(5):569-584. doi: 10.1089/hum.2017.136.

PMID:
29562762
20.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z.

Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31.

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