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Items: 1 to 20 of 144

1.

Non-viral therapeutic cell engineering with the Sleeping Beauty transposon system.

Hudecek M, Ivics Z.

Curr Opin Genet Dev. 2018 Jun 22;52:100-108. doi: 10.1016/j.gde.2018.06.003. [Epub ahead of print] Review.

PMID:
29957586
2.

The Antibiotic-free pFAR4 Vector Paired with the Sleeping Beauty Transposon System Mediates Efficient Transgene Delivery in Human Cells.

Pastor M, Johnen S, Harmening N, Quiviger M, Pailloux J, Kropp M, Walter P, Ivics Z, Izsvák Z, Thumann G, Scherman D, Marie C.

Mol Ther Nucleic Acids. 2018 Jun 1;11:57-67. doi: 10.1016/j.omtn.2017.12.017. Epub 2017 Dec 30.

3.

Efficient Non-Viral T-Cell Engineering by Sleeping Beauty Minicircles Diminishing DNA Toxicity and miRNAs Silencing the Endogenous T-Cell Receptors.

Clauss J, Obenaus M, Miskey C, Ivics Z, Izsvák Z, Uckert W, Bunse M.

Hum Gene Ther. 2018 May;29(5):569-584. doi: 10.1089/hum.2017.136.

PMID:
29562762
4.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z.

Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31.

5.

High and long-term von Willebrand factor expression after Sleeping Beauty transposon-mediated gene therapy in a mouse model of severe von Willebrand disease.

Portier I, Vanhoorelbeke K, Verhenne S, Pareyn I, Vandeputte N, Deckmyn H, Goldenberg DS, Samal HB, Singh M, Ivics Z, Izsvák Z, De Meyer SF.

J Thromb Haemost. 2018 Mar;16(3):592-604. doi: 10.1111/jth.13938. Epub 2018 Jan 31.

PMID:
29288565
6.

Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery.

Garcia-Garcia L, Recalde S, Hernandez M, Bezunartea J, Rodriguez-Madoz JR, Johnen S, Diarra S, Marie C, Izsvák Z, Ivics Z, Scherman D, Kropp M, Thumann G, Prosper F, Fernandez-Robredo P, Garcia-Layana A.

Mol Ther Nucleic Acids. 2017 Dec 15;9:1-11. doi: 10.1016/j.omtn.2017.08.001. Epub 2017 Aug 12.

7.

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails.

Benleulmi MS, Matysiak J, Robert X, Miskey C, Mauro E, Lapaillerie D, Lesbats P, Chaignepain S, Henriquez DR, Calmels C, Oladosu O, Thierry E, Leon O, Lavigne M, Andreola ML, Delelis O, Ivics Z, Ruff M, Gouet P, Parissi V.

Retrovirology. 2017 Nov 28;14(1):54. doi: 10.1186/s12977-017-0378-x.

8.

Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells.

Ade CM, Derbes RS, Wagstaff BJ, Linker SB, White TB, Deharo D, Belancio VP, Ivics Z, Roy-Engel AM.

Gene. 2018 Feb 5;642:188-198. doi: 10.1016/j.gene.2017.11.033. Epub 2017 Nov 14.

9.

Human Genome Editing in the Clinic: New Challenges in Regulatory Benefit-Risk Assessment.

Abou-El-Enein M, Cathomen T, Ivics Z, June CH, Renner M, Schneider CK, Bauer G.

Cell Stem Cell. 2017 Oct 5;21(4):427-430. doi: 10.1016/j.stem.2017.09.007.

PMID:
28985524
10.

Gene Therapy with the Sleeping Beauty Transposon System.

Kebriaei P, Izsvák Z, Narayanavari SA, Singh H, Ivics Z.

Trends Genet. 2017 Nov;33(11):852-870. doi: 10.1016/j.tig.2017.08.008. Epub 2017 Sep 27. Review.

PMID:
28964527
11.

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.

Elling U, Wimmer RA, Leibbrandt A, Burkard T, Michlits G, Leopoldi A, Micheler T, Abdeen D, Zhuk S, Aspalter IM, Handl C, Liebergesell J, Hubmann M, Husa AM, Kinzer M, Schuller N, Wetzel E, van de Loo N, Martinez JAZ, Estoppey D, Riedl R, Yang F, Fu B, Dechat T, Ivics Z, Agu CA, Bell O, Blaas D, Gerhardt H, Hoepfner D, Stark A, Penninger JM.

Nature. 2017 Oct 5;550(7674):114-118. doi: 10.1038/nature24027. Epub 2017 Sep 27.

PMID:
28953874
12.

Generation of an immortalized mesenchymal stem cell line producing a secreted biosensor protein for glucose monitoring.

Siska EK, Weisman I, Romano J, Ivics Z, Izsvák Z, Barkai U, Petrakis S, Koliakos G.

PLoS One. 2017 Sep 26;12(9):e0185498. doi: 10.1371/journal.pone.0185498. eCollection 2017.

13.

Transposons As Tools for Functional Genomics in Vertebrate Models.

Kawakami K, Largaespada DA, Ivics Z.

Trends Genet. 2017 Nov;33(11):784-801. doi: 10.1016/j.tig.2017.07.006. Epub 2017 Sep 6. Review.

PMID:
28888423
14.

Wide Awake and Ready to Move: 20 Years of Non-Viral Therapeutic Genome Engineering with the Sleeping Beauty Transposon System.

Hodge R, Narayanavari SA, Izsvák Z, Ivics Z.

Hum Gene Ther. 2017 Oct;28(10):842-855. doi: 10.1089/hum.2017.130. Review.

PMID:
28870121
15.

Alterations in SCAI Expression during Cell Plasticity, Fibrosis and Cancer.

Gasparics Á, Kökény G, Fintha A, Bencs R, Mózes MM, Ágoston EI, Buday A, Ivics Z, Hamar P, Győrffy B, Rosivall L, Sebe A.

Pathol Oncol Res. 2018 Jul;24(3):641-651. doi: 10.1007/s12253-017-0293-4. Epub 2017 Aug 16.

PMID:
28815470
16.

The Piwi-piRNA pathway: road to immortality.

Sturm Á, Perczel A, Ivics Z, Vellai T.

Aging Cell. 2017 Oct;16(5):906-911. doi: 10.1111/acel.12630. Epub 2017 Jun 27.

17.

Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.

Hudecek M, Izsvák Z, Johnen S, Renner M, Thumann G, Ivics Z.

Crit Rev Biochem Mol Biol. 2017 Aug;52(4):355-380. doi: 10.1080/10409238.2017.1304354. Epub 2017 Apr 12. Review. Erratum in: Crit Rev Biochem Mol Biol. 2017 Aug;52(4):i.

PMID:
28402189
18.

Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids.

Thumann G, Harmening N, Prat-Souteyrand C, Marie C, Pastor M, Sebe A, Miskey C, Hurst LD, Diarra S, Kropp M, Walter P, Scherman D, Ivics Z, Izsvák Z, Johnen S.

Mol Ther Nucleic Acids. 2017 Mar 17;6:302-314. doi: 10.1016/j.omtn.2017.02.002. Epub 2017 Feb 10.

19.

Assessing Tn5 and Sleeping Beauty for transpositional transgenesis by cytoplasmic injection into bovine and ovine zygotes.

Bevacqua RJ, Fernandez-Martin R, Canel NG, Gibbons A, Texeira D, Lange F, Vans Landschoot G, Savy V, Briski O, Hiriart MI, Grueso E, Ivics Z, Taboga O, Kues WA, Ferraris S, Salamone DF.

PLoS One. 2017 Mar 16;12(3):e0174025. doi: 10.1371/journal.pone.0174025. eCollection 2017.

20.

Transposition of the bamboo Mariner-like element Ppmar1 in yeast.

Zhou MB, Hu H, Miskey C, Lazarow K, Ivics Z, Kunze R, Yang G, Izsvák Z, Tang DQ.

Mol Phylogenet Evol. 2017 Apr;109:367-374. doi: 10.1016/j.ympev.2017.02.005. Epub 2017 Feb 9.

PMID:
28189615

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