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Electron Microscopy-Based Comparison and Investigation of the Morphology of Exosomes Derived from Hepatocellular Carcinoma Cells Isolated at Different Centrifugal Speeds.

Deng JH, Li ZJ, Wang ZX, Feng J, Huang XJ, Zeng ZM.

Microsc Microanal. 2020 Feb 13:1-9. doi: 10.1017/S1431927620000070. [Epub ahead of print]


Exosomes purified from a single cell type have diverse morphology.

Zabeo D, Cvjetkovic A, Lässer C, Schorb M, Lötvall J, Höög JL.

J Extracell Vesicles. 2017 Jun 20;6(1):1329476. doi: 10.1080/20013078.2017.1329476. eCollection 2017.


Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts.

Zhou Y, Ren H, Dai B, Li J, Shang L, Huang J, Shi X.

J Exp Clin Cancer Res. 2018 Dec 27;37(1):324. doi: 10.1186/s13046-018-0965-2.


Comparison of exosomes purified via ultracentrifugation (UC) and Total Exosome Isolation (TEI) reagent from the serum of Marek's disease virus (MDV)-vaccinated and tumor-bearing chickens.

Nath Neerukonda S, Egan NA, Patria J, Assakhi I, Tavlarides-Hontz P, Modla S, Muñoz ER, Hudson MB, Parcells MS.

J Virol Methods. 2019 Jan;263:1-9. doi: 10.1016/j.jviromet.2018.10.004. Epub 2018 Oct 11.


An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells.

Gupta S, Rawat S, Arora V, Kottarath SK, Dinda AK, Vaishnav PK, Nayak B, Mohanty S.

Stem Cell Res Ther. 2018 Jul 4;9(1):180. doi: 10.1186/s13287-018-0923-0.


The role of extracellular vesicles in mediating progression, metastasis and potential treatment of hepatocellular carcinoma.

Yang N, Li S, Li G, Zhang S, Tang X, Ni S, Jian X, Xu C, Zhu J, Lu M.

Oncotarget. 2017 Jan 10;8(2):3683-3695. doi: 10.18632/oncotarget.12465. Review.


Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes.

Crescitelli R, Lässer C, Szabó TG, Kittel A, Eldh M, Dianzani I, Buzás EI, Lötvall J.

J Extracell Vesicles. 2013 Sep 12;2. doi: 10.3402/jev.v2i0.20677. eCollection 2013.


Exosomes derived from HCC cells with different invasion characteristics mediated EMT through TGF-β/Smad signaling pathway.

Qu Z, Feng J, Pan H, Jiang Y, Duan Y, Fa Z.

Onco Targets Ther. 2019 Aug 23;12:6897-6905. doi: 10.2147/OTT.S209413. eCollection 2019.


Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.

Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ.

Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.


HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway.

Chen L, Guo P, He Y, Chen Z, Chen L, Luo Y, Qi L, Liu Y, Wu Q, Cui Y, Fang F, Zhang X, Song T, Guo H.

Cell Death Dis. 2018 May 1;9(5):513. doi: 10.1038/s41419-018-0534-9.


Purified horse milk exosomes contain an unpredictable small number of major proteins.

Sedykh SE, Purvinish LV, Monogarov AS, Burkova EE, Grigor'eva AE, Bulgakov DV, Dmitrenok PS, Vlassov VV, Ryabchikova EI, Nevinsky GA.

Biochim Open. 2017 Mar 1;4:61-72. doi: 10.1016/j.biopen.2017.02.004. eCollection 2017 Jun.


Extracellular vesicles mediate signaling between the aqueous humor producing and draining cells in the ocular system.

Lerner N, Avissar S, Beit-Yannai E.

PLoS One. 2017 Feb 27;12(2):e0171153. doi: 10.1371/journal.pone.0171153. eCollection 2017.


Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro.

Qu Z, Wu J, Wu J, Luo D, Jiang C, Ding Y.

J Exp Clin Cancer Res. 2016 Sep 30;35(1):159.


Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.

Maroto R, Zhao Y, Jamaluddin M, Popov VL, Wang H, Kalubowilage M, Zhang Y, Luisi J, Sun H, Culbertson CT, Bossmann SH, Motamedi M, Brasier AR.

J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.


Exosomes and Hepatocellular Carcinoma: From Bench to Bedside.

Sasaki R, Kanda T, Yokosuka O, Kato N, Matsuoka S, Moriyama M.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1406. doi: 10.3390/ijms20061406. Review.


Exosome enrichment of human serum using multiple cycles of centrifugation.

Kim J, Tan Z, Lubman DM.

Electrophoresis. 2015 Sep;36(17):2017-26. doi: 10.1002/elps.201500131. Epub 2015 Jul 15.


Comparative analysis of discrete exosome fractions obtained by differential centrifugation.

Jeppesen DK, Hvam ML, Primdahl-Bengtson B, Boysen AT, Whitehead B, Dyrskjøt L, Orntoft TF, Howard KA, Ostenfeld MS.

J Extracell Vesicles. 2014 Nov 6;3:25011. doi: 10.3402/jev.v3.25011. eCollection 2014.


[Contamination of exosome preparations, isolated from biological fluids].

Grigor'eva AE, Dyrkheeva NS, Bryzgunova OE, Tamkovich SN, Chelobanov BP, Ryabchikova EI.

Biomed Khim. 2017 Jan;63(1):91-96. doi: 10.18097/PBMC2017630191. Russian.


A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents.

Helwa I, Cai J, Drewry MD, Zimmerman A, Dinkins MB, Khaled ML, Seremwe M, Dismuke WM, Bieberich E, Stamer WD, Hamrick MW, Liu Y.

PLoS One. 2017 Jan 23;12(1):e0170628. doi: 10.1371/journal.pone.0170628. eCollection 2017.


Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells.

Oksvold MP, Kullmann A, Forfang L, Kierulf B, Li M, Brech A, Vlassov AV, Smeland EB, Neurauter A, Pedersen KW.

Clin Ther. 2014 Jun 1;36(6):847-862.e1. doi: 10.1016/j.clinthera.2014.05.010.

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