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Items: 1 to 20 of 100

1.

Long-term HIV-1 Tat Expression in the Brain Led to Neurobehavioral, Pathological, and Epigenetic Changes Reminiscent of Accelerated Aging.

Zhao X, Fan Y, Vann PH, Wong JM, Sumien N, He JJ.

Aging Dis. 2020 Feb 1;11(1):93-107. doi: 10.14336/AD.2019.0323. eCollection 2020 Feb.

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Doxycycline-inducible and astrocyte-specific HIV-1 Tat transgenic mice (iTat) as an HIV/neuroAIDS model.

Langford D, Oh Kim B, Zou W, Fan Y, Rahimain P, Liu Y, He JJ.

J Neurovirol. 2018 Apr;24(2):168-179. doi: 10.1007/s13365-017-0598-9. Epub 2017 Nov 15. Review.

4.

Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis.

Periyasamy P, Thangaraj A, Guo ML, Hu G, Callen S, Buch S.

J Neurosci. 2018 Jun 6;38(23):5367-5383. doi: 10.1523/JNEUROSCI.3474-17.2018. Epub 2018 May 14.

6.

Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse.

Carey AN, Sypek EI, Singh HD, Kaufman MJ, McLaughlin JP.

Behav Brain Res. 2012 Apr 1;229(1):48-56. doi: 10.1016/j.bbr.2011.12.019. Epub 2011 Dec 20.

8.

Exposure to HIV-1 Tat in brain impairs sensorimotor gating and activates microglia in limbic and extralimbic brain regions of male mice.

Paris JJ, Singh HD, Carey AN, McLaughlin JP.

Behav Brain Res. 2015 Sep 15;291:209-218. doi: 10.1016/j.bbr.2015.05.021. Epub 2015 May 22.

9.

Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity.

Silva JN, Polesskaya O, Wei HS, Rasheed IY, Chamberlain JM, Nishimura C, Feng C, Dewhurst S.

Microcirculation. 2014 Oct;21(7):664-76. doi: 10.1111/micc.12145.

10.

Central HIV-1 Tat exposure elevates anxiety and fear conditioned responses of male mice concurrent with altered mu-opioid receptor-mediated G-protein activation and β-arrestin 2 activity in the forebrain.

Hahn YK, Paris JJ, Lichtman AH, Hauser KF, Sim-Selley LJ, Selley DE, Knapp PE.

Neurobiol Dis. 2016 Aug;92(Pt B):124-36. doi: 10.1016/j.nbd.2016.01.014. Epub 2016 Feb 1.

11.

Methamphetamine augment HIV-1 Tat mediated memory deficits by altering the expression of synaptic proteins and neurotrophic factors.

Nookala AR, Schwartz DC, Chaudhari NS, Glazyrin A, Stephens EB, Berman NEJ, Kumar A.

Brain Behav Immun. 2018 Jul;71:37-51. doi: 10.1016/j.bbi.2018.04.018. Epub 2018 May 2.

12.

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

Fitting S, Stevens DL, Khan FA, Scoggins KL, Enga RM, Beardsley PM, Knapp PE, Dewey WL, Hauser KF.

J Pharmacol Exp Ther. 2016 Jan;356(1):96-105. doi: 10.1124/jpet.115.226407. Epub 2015 Nov 5.

13.

Selective Vulnerability of Striatal D2 versus D1 Dopamine Receptor-Expressing Medium Spiny Neurons in HIV-1 Tat Transgenic Male Mice.

Schier CJ, Marks WD, Paris JJ, Barbour AJ, McLane VD, Maragos WF, McQuiston AR, Knapp PE, Hauser KF.

J Neurosci. 2017 Jun 7;37(23):5758-5769. doi: 10.1523/JNEUROSCI.0622-17.2017. Epub 2017 May 4.

14.

Human Immunodeficiency Virus Type 1 gp120 and Tat Induce Mitochondrial Fragmentation and Incomplete Mitophagy in Human Neurons.

Teodorof-Diedrich C, Spector SA.

J Virol. 2018 Oct 29;92(22). pii: e00993-18. doi: 10.1128/JVI.00993-18. Print 2018 Nov 15.

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16.

Mechanisms of HIV-tat-induced phosphorylation of N-methyl-D-aspartate receptor subunit 2A in human primary neurons: implications for neuroAIDS pathogenesis.

King JE, Eugenin EA, Hazleton JE, Morgello S, Berman JW.

Am J Pathol. 2010 Jun;176(6):2819-30. doi: 10.2353/ajpath.2010.090642. Epub 2010 May 6.

17.

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior.

Hahn YK, Podhaizer EM, Farris SP, Miles MF, Hauser KF, Knapp PE.

Brain Struct Funct. 2015 Mar;220(2):605-23. doi: 10.1007/s00429-013-0676-6. Epub 2013 Dec 19.

18.

HIV-1 Tat causes cognitive deficits and selective loss of parvalbumin, somatostatin, and neuronal nitric oxide synthase expressing hippocampal CA1 interneuron subpopulations.

Marks WD, Paris JJ, Schier CJ, Denton MD, Fitting S, McQuiston AR, Knapp PE, Hauser KF.

J Neurovirol. 2016 Dec;22(6):747-762. Epub 2016 May 13.

19.

Novel insights into role of miR-320a-VDAC1 axis in astrocyte-mediated neuronal damage in neuroAIDS.

Fatima M, Prajapati B, Saleem K, Kumari R, Mohindar Singh Singal C, Seth P.

Glia. 2017 Feb;65(2):250-263. doi: 10.1002/glia.23089. Epub 2016 Oct 20.

PMID:
27761954
20.

HIV-1 Tat contributes to Alzheimer's disease-like pathology in PSAPP mice.

Giunta B, Hou H, Zhu Y, Rrapo E, Tian J, Takashi M, Commins D, Singer E, He J, Fernandez F, Tan J.

Int J Clin Exp Pathol. 2009;2(5):433-43. Epub 2009 Jan 30.

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