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Items: 1 to 20 of 104


Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration.

Voigt AP, Mulfaul K, Mullin NK, Flamme-Wiese MJ, Giacalone JC, Stone EM, Tucker BA, Scheetz TE, Mullins RF.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24100-24107. doi: 10.1073/pnas.1914143116. Epub 2019 Nov 11.


Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration.

Bhutto IA, McLeod DS, Hasegawa T, Kim SY, Merges C, Tong P, Lutty GA.

Exp Eye Res. 2006 Jan;82(1):99-110. Epub 2005 Jul 12.


Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration.

McLeod DS, Taomoto M, Otsuji T, Green WR, Sunness JS, Lutty GA.

Invest Ophthalmol Vis Sci. 2002 Jun;43(6):1986-93.


Relationship between RPE and choriocapillaris in age-related macular degeneration.

McLeod DS, Grebe R, Bhutto I, Merges C, Baba T, Lutty GA.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4982-91. doi: 10.1167/iovs.09-3639. Epub 2009 Apr 8.


Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration.

Bhutto IA, Kim SY, McLeod DS, Merges C, Fukai N, Olsen BR, Lutty GA.

Invest Ophthalmol Vis Sci. 2004 May;45(5):1544-52.


Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration.

Mullins RF, Johnson MN, Faidley EA, Skeie JM, Huang J.

Invest Ophthalmol Vis Sci. 2011 Mar 1;52(3):1606-12. doi: 10.1167/iovs.10-6476.


Changes in choriocapillaris and retinal pigment epithelium in age-related macular degeneration.

Lutty G, Grunwald J, Majji AB, Uyama M, Yoneya S.

Mol Vis. 1999 Nov 3;5:35. Review.


Loss of endothelial planar cell polarity and cellular clearance mechanisms in age-related macular degeneration.

Campos MM, Abu-Asab MS.

Ultrastruct Pathol. 2017 Sep-Oct;41(5):312-319. doi: 10.1080/01913123.2017.1348418. Epub 2017 Aug 10.


Macular and peripheral distribution of ICAM-1 in the human choriocapillaris and retina.

Mullins RF, Skeie JM, Malone EA, Kuehn MH.

Mol Vis. 2006 Mar 30;12:224-35.


Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation.

Blaauwgeers HG, Holtkamp GM, Rutten H, Witmer AN, Koolwijk P, Partanen TA, Alitalo K, Kroon ME, Kijlstra A, van Hinsbergh VW, Schlingemann RO.

Am J Pathol. 1999 Aug;155(2):421-8.


Current concepts in the pathogenesis of age-related macular degeneration.

Zarbin MA.

Arch Ophthalmol. 2004 Apr;122(4):598-614. Review.


Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks.

Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, Cooper JB, Hageman GS, Anderson DH, Johnson LV, Radeke MJ.

Genome Med. 2012 Feb 24;4(2):16. doi: 10.1186/gm315.


Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells.

Whitmore SS, Braun TA, Skeie JM, Haas CM, Sohn EH, Stone EM, Scheetz TE, Mullins RF.

Mol Vis. 2013 Nov 16;19:2274-97. eCollection 2013.


Choriocapillaris Degeneration in Geographic Atrophy.

Sohn EH, Flamme-Wiese MJ, Whitmore SS, Workalemahu G, Marneros AG, Boese EA, Kwon YH, Wang K, Abramoff MD, Tucker BA, Stone EM, Mullins RF.

Am J Pathol. 2019 Jul;189(7):1473-1480. doi: 10.1016/j.ajpath.2019.04.005. Epub 2019 Apr 30.


The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration.

Chen H, Liu B, Lukas TJ, Neufeld AH.

PLoS One. 2008 Jun 4;3(6):e2339. doi: 10.1371/journal.pone.0002339.


Morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in eyes with age-related macular degeneration.

Spraul CW, Lang GE, Grossniklaus HE.

Invest Ophthalmol Vis Sci. 1996 Dec;37(13):2724-35.


Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration.

Biesemeier A, Taubitz T, Julien S, Yoeruek E, Schraermeyer U.

Neurobiol Aging. 2014 Nov;35(11):2562-2573. doi: 10.1016/j.neurobiolaging.2014.05.003. Epub 2014 May 10.


Characterization of a tissue-engineered choroid.

Djigo AD, Bérubé J, Landreville S, Proulx S.

Acta Biomater. 2019 Jan 15;84:305-316. doi: 10.1016/j.actbio.2018.11.033. Epub 2018 Nov 23.


Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration.

Seddon JM, McLeod DS, Bhutto IA, Villalonga MB, Silver RE, Wenick AS, Edwards MM, Lutty GA.

JAMA Ophthalmol. 2016 Nov 1;134(11):1272-1280. doi: 10.1001/jamaophthalmol.2016.3519.

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