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Items: 1 to 20 of 101

1.

The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage.

Koerver L, Papadopoulos C, Liu B, Kravic B, Rota G, Brecht L, Veenendaal T, Polajnar M, Bluemke A, Ehrmann M, Klumperman J, Jäättelä M, Behrends C, Meyer H.

EMBO Rep. 2019 Aug 21:e48014. doi: 10.15252/embr.201948014. [Epub ahead of print]

2.

The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy.

Mizushima N.

EMBO Rep. 2019 Sep 15:e49104. doi: 10.15252/embr.201949104. [Epub ahead of print]

PMID:
31523916
3.

Repair or Lysophagy: Dealing with Damaged Lysosomes.

Papadopoulos C, Kravic B, Meyer H.

J Mol Biol. 2019 Aug 23. pii: S0022-2836(19)30519-4. doi: 10.1016/j.jmb.2019.08.010. [Epub ahead of print] Review.

PMID:
31449799
4.

Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy.

Papadopoulos C, Meyer H.

Curr Biol. 2017 Dec 18;27(24):R1330-R1341. doi: 10.1016/j.cub.2017.11.012. Review.

5.

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.

Papadopoulos C, Kirchner P, Bug M, Grum D, Koerver L, Schulze N, Poehler R, Dressler A, Fengler S, Arhzaouy K, Lux V, Ehrmann M, Weihl CC, Meyer H.

EMBO J. 2017 Jan 17;36(2):135-150. doi: 10.15252/embj.201695148. Epub 2016 Oct 17.

6.

VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.

Arhzaouy K, Papadopoulos C, Schulze N, Pittman SK, Meyer H, Weihl CC.

Autophagy. 2019 Jun;15(6):1082-1099. doi: 10.1080/15548627.2019.1569933. Epub 2019 Jan 29.

PMID:
30654731
7.

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.

Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, Iwai K, Saeki Y, Yoshimori T, Matsuda N, Tanaka K.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8574-8579. doi: 10.1073/pnas.1702615114. Epub 2017 Jul 25.

8.

Assays to Monitor Lysophagy.

Chu YP, Hung YH, Chang HY, Yang WY.

Methods Enzymol. 2017;588:231-244. doi: 10.1016/bs.mie.2016.09.083. Epub 2016 Nov 29.

PMID:
28237104
9.

ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival.

Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H.

EMBO J. 2018 Nov 2;37(21). pii: e99753. doi: 10.15252/embj.201899753. Epub 2018 Oct 12.

PMID:
30314966
10.

Spatiotemporally controlled induction of autophagy-mediated lysosome turnover.

Hung YH, Chen LM, Yang JY, Yang WY.

Nat Commun. 2013;4:2111. doi: 10.1038/ncomms3111.

PMID:
23817530
11.

Lysophagy: A Method for Monitoring Lysosomal Rupture Followed by Autophagy-Dependent Recovery.

Otomo T, Yoshimori T.

Methods Mol Biol. 2017;1594:141-149. doi: 10.1007/978-1-4939-6934-0_8.

PMID:
28456980
12.

The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity.

Li Y, Chen B, Zou W, Wang X, Wu Y, Zhao D, Sun Y, Liu Y, Chen L, Miao L, Yang C, Wang X.

J Cell Biol. 2016 Oct 24;215(2):167-185. Epub 2016 Oct 17.

13.

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.

Ivankovic D, Chau KY, Schapira AH, Gegg ME.

J Neurochem. 2016 Jan;136(2):388-402. doi: 10.1111/jnc.13412. Epub 2015 Nov 24.

14.

The anti-apoptotic ubiquitin conjugating enzyme BIRC6/BRUCE regulates autophagosome-lysosome fusion.

Ikeda F.

Autophagy. 2018;14(7):1283-1284. doi: 10.1080/15548627.2018.1471311. Epub 2018 Jul 20.

15.

IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation.

Bayraktar O, Oral O, Kocaturk NM, Akkoc Y, Eberhart K, Kosar A, Gozuacik D.

PLoS One. 2016 Oct 21;11(10):e0164864. doi: 10.1371/journal.pone.0164864. eCollection 2016. Erratum in: PLoS One. 2016 Nov 18;11(11):e0167192.

16.

Ubiquitination is required for the initial removal of paternal organelles in C. elegans.

Molina P, Lim Y, Boyd L.

Dev Biol. 2019 Sep 15;453(2):168-179. doi: 10.1016/j.ydbio.2019.05.015. Epub 2019 May 30.

PMID:
31153831
17.

UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene.

Wake NC, Ricketts CJ, Morris MR, Prigmore E, Gribble SM, Skytte AB, Brown M, Clarke N, Banks RE, Hodgson S, Turnell AS, Maher ER, Woodward ER.

Hum Mutat. 2013 Dec;34(12):1650-61. doi: 10.1002/humu.22433. Epub 2013 Oct 7.

18.

Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.

Zhou J, Tan SH, Nicolas V, Bauvy C, Yang ND, Zhang J, Xue Y, Codogno P, Shen HM.

Cell Res. 2013 Apr;23(4):508-23. doi: 10.1038/cr.2013.11. Epub 2013 Jan 22.

19.

SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy.

Wang Y, Ballar P, Zhong Y, Zhang X, Liu C, Zhang YJ, Monteiro MJ, Li J, Fang S.

PLoS One. 2011;6(8):e24478. doi: 10.1371/journal.pone.0024478. Epub 2011 Aug 31.

20.

Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis.

He J, Zhu Q, Wani G, Sharma N, Han C, Qian J, Pentz K, Wang QE, Wani AA.

J Biol Chem. 2014 Sep 26;289(39):27278-89. doi: 10.1074/jbc.M114.589812. Epub 2014 Aug 12.

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