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Items: 1 to 20 of 98

1.

The Role of Structural Polymorphism in Driving the Mechanical Performance of the Alzheimer's Beta Amyloid Fibrils.

Grasso G, Rebella M, Morbiducci U, Tuszynski JA, Danani A, Deriu MA.

Front Bioeng Biotechnol. 2019 Apr 24;7:83. doi: 10.3389/fbioe.2019.00083. eCollection 2019.

2.

Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies.

Grasso G, Rebella M, Muscat S, Morbiducci U, Tuszynski J, Danani A, Deriu MA.

Int J Mol Sci. 2018 Feb 14;19(2). pii: E571. doi: 10.3390/ijms19020571.

3.

Alzheimer's abeta(1-40) amyloid fibrils feature size-dependent mechanical properties.

Xu Z, Paparcone R, Buehler MJ.

Biophys J. 2010 May 19;98(10):2053-62. doi: 10.1016/j.bpj.2009.12.4317.

4.

Mutations alter the geometry and mechanical properties of Alzheimer's Aβ(1-40) amyloid fibrils.

Paparcone R, Pires MA, Buehler MJ.

Biochemistry. 2010 Oct 19;49(41):8967-77. doi: 10.1021/bi100953t.

PMID:
20731379
5.

Amyloid Fibril Design: Limiting Structural Polymorphism in Alzheimer's Aβ Protofilaments.

Tywoniuk B, Yuan Y, McCartan S, Szydłowska BM, Tofoleanu F, Brooks BR, Buchete NV.

J Phys Chem B. 2018 Dec 13;122(49):11535-11545. doi: 10.1021/acs.jpcb.8b07423. Epub 2018 Nov 29.

6.

S14G-humanin inhibits Aβ1-42 fibril formation, disaggregates preformed fibrils, and protects against Aβ-induced cytotoxicity in vitro.

Zhang W, Du Y, Bai M, Xi Y, Li Z, Miao J.

J Pept Sci. 2013 Mar;19(3):159-65. doi: 10.1002/psc.2484. Epub 2013 Jan 24. Retraction in: J Pept Sci. 2016 Jun;22(6):434.

PMID:
23349038
7.

Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation.

Villalobos Acosta DMÁ, Chimal Vega B, Correa Basurto J, Fragoso Morales LG, Rosales Hernández MC.

Int J Mol Sci. 2018 Aug 16;19(8). pii: E2415. doi: 10.3390/ijms19082415. Review.

8.

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes.

Qiang W, Yau WM, Lu JX, Collinge J, Tycko R.

Nature. 2017 Jan 12;541(7636):217-221. doi: 10.1038/nature20814. Epub 2017 Jan 4.

9.

Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange.

Carulla N, Zhou M, Giralt E, Robinson CV, Dobson CM.

Acc Chem Res. 2010 Aug 17;43(8):1072-9. doi: 10.1021/ar9002784.

PMID:
20557067
10.

The potential inhibitory effect of β-casein on the aggregation and deposition of Aβ1-42 fibrils in Alzheimer's disease: insight from in-vitro and in-silico studies.

Hojati S, Ghahghaei A, Lagzian M.

J Biomol Struct Dyn. 2018 Jun;36(8):2118-2130. doi: 10.1080/07391102.2017.1345326. Epub 2017 Jul 4.

PMID:
28633568
11.

Two distinct β-sheet structures in Italian-mutant amyloid-beta fibrils: a potential link to different clinical phenotypes.

Hubin E, Deroo S, Schierle GK, Kaminski C, Serpell L, Subramaniam V, van Nuland N, Broersen K, Raussens V, Sarroukh R.

Cell Mol Life Sci. 2015 Dec;72(24):4899-913. doi: 10.1007/s00018-015-1983-2. Epub 2015 Jul 21.

12.

Atomistic simulation of nanomechanical properties of Alzheimer's Abeta(1-40) amyloid fibrils under compressive and tensile loading.

Paparcone R, Keten S, Buehler MJ.

J Biomech. 2010 Apr 19;43(6):1196-201. doi: 10.1016/j.jbiomech.2009.11.026. Epub 2009 Dec 30.

PMID:
20044089
13.

Cooperative structural transitions in amyloid-like aggregation.

Steckmann T, Bhandari YR, Chapagain PP, Gerstman BS.

J Chem Phys. 2017 Apr 7;146(13):135103. doi: 10.1063/1.4979516.

PMID:
28390382
14.

Mapping the Broad Structural and Mechanical Properties of Amyloid Fibrils.

Lamour G, Nassar R, Chan PHW, Bozkurt G, Li J, Bui JM, Yip CK, Mayor T, Li H, Wu H, Gsponer JA.

Biophys J. 2017 Feb 28;112(4):584-594. doi: 10.1016/j.bpj.2016.12.036.

15.

Role of sequence and structural polymorphism on the mechanical properties of amyloid fibrils.

Yoon G, Lee M, Kim JI, Na S, Eom K.

PLoS One. 2014 Feb 14;9(2):e88502. doi: 10.1371/journal.pone.0088502. eCollection 2014.

16.

Elucidating the Structures of Amyloid Oligomers with Macrocyclic β-Hairpin Peptides: Insights into Alzheimer's Disease and Other Amyloid Diseases.

Kreutzer AG, Nowick JS.

Acc Chem Res. 2018 Mar 20;51(3):706-718. doi: 10.1021/acs.accounts.7b00554. Epub 2018 Mar 6. Review.

17.

Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.

Takahashi T, Mihara H.

Acc Chem Res. 2008 Oct;41(10):1309-18. doi: 10.1021/ar8000475.

PMID:
18937396
18.

Direct evidence for self-propagation of different amyloid-β fibril conformations.

Spirig T, Ovchinnikova O, Vagt T, Glockshuber R.

Neurodegener Dis. 2014;14(3):151-9. doi: 10.1159/000363623. Epub 2014 Oct 4.

19.

Insights into Stabilizing Forces in Amyloid Fibrils of Differing Sizes from Polarizable Molecular Dynamics Simulations.

Davidson DS, Brown AM, Lemkul JA.

J Mol Biol. 2018 Oct 12;430(20):3819-3834. doi: 10.1016/j.jmb.2018.05.020. Epub 2018 May 18.

PMID:
29782833
20.

Molecular structures of amyloid and prion fibrils: consensus versus controversy.

Tycko R, Wickner RB.

Acc Chem Res. 2013 Jul 16;46(7):1487-96. doi: 10.1021/ar300282r. Epub 2013 Jan 7. Review.

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