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Items: 1 to 20 of 98

1.

Discretionary Transduction of MMP-Sensitized Tousled in Head and Neck Cancer.

Nair RP, Timiri Shanmugam PS, Sunavala-Dossabhoy G.

Mol Ther Oncolytics. 2019 Mar 20;14:57-65. doi: 10.1016/j.omto.2019.02.003. eCollection 2019 Sep 27.

2.

TAT-mediated delivery of Tousled protein to salivary glands protects against radiation-induced hypofunction.

Sunavala-Dossabhoy G, Palaniyandi S, Richardson C, De Benedetti A, Schrott L, Caldito G.

Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):257-65. doi: 10.1016/j.ijrobp.2011.10.064. Epub 2012 Jan 26.

PMID:
22285666
3.

Adenoviral delivery of Tousled kinase for the protection of salivary glands against ionizing radiation damage.

Palaniyandi S, Odaka Y, Green W, Abreo F, Caldito G, De Benedetti A, Sunavala-Dossabhoy G.

Gene Ther. 2011 Mar;18(3):275-82. doi: 10.1038/gt.2010.142. Epub 2010 Nov 4.

PMID:
21048794
4.

Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia.

Timiri Shanmugam PS, Dayton RD, Palaniyandi S, Abreo F, Caldito G, Klein RL, Sunavala-Dossabhoy G.

Hum Gene Ther. 2013 Jun;24(6):604-12. doi: 10.1089/hum.2012.235.

5.

Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cells.

Timiri Shanmugam PS, Nair RP, De Benedetti A, Caldito G, Abreo F, Sunavala-Dossabhoy G.

Free Radic Biol Med. 2016 Apr;93:217-26. doi: 10.1016/j.freeradbiomed.2015.12.029. Epub 2016 Feb 15.

6.

Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair.

Sunavala-Dossabhoy G, De Benedetti A.

DNA Repair (Amst). 2009 Jan 1;8(1):87-102. doi: 10.1016/j.dnarep.2008.09.005. Epub 2008 Nov 5.

PMID:
18940270
7.

Role of cytokines in the destruction of acinar structure in Sjögren's syndrome salivary glands.

Azuma M, Motegi K, Aota K, Hayashi Y, Sato M.

Lab Invest. 1997 Sep;77(3):269-80.

PMID:
9314950
8.
9.

Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.

Imanishi Y, Fujii M, Tokumaru Y, Tomita T, Kanke M, Kanzaki J, Kameyama K, Otani Y, Sato H.

Hum Pathol. 2000 Aug;31(8):895-904.

PMID:
10987249
10.
11.

The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks.

Sunavala-Dossabhoy G, Balakrishnan SK, Sen S, Nuthalapaty S, De Benedetti A.

BMC Mol Biol. 2005 Sep 12;6:19.

12.

Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma.

Yoshizaki T, Sato H, Maruyama Y, Murono S, Furukawa M, Park CS, Seiki M.

Cancer. 1997 Jan 1;79(1):139-44.

PMID:
8988738
13.

A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed.

Li Y, DeFatta R, Anthony C, Sunavala G, De Benedetti A.

Oncogene. 2001 Feb 8;20(6):726-38.

14.

Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.

Tomita T, Fujii M, Tokumaru Y, Imanishi Y, Kanke M, Yamashita T, Ishiguro R, Kanzaki J, Kameyama K, Otani Y.

Cancer Lett. 2000 Aug 1;156(1):83-91.

PMID:
10840163
15.

TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.

Canfield C, Rains J, De Benedetti A.

BMC Mol Biol. 2009 Dec 20;10:110. doi: 10.1186/1471-2199-10-110.

17.

Correlation of TLK1B in elevation and recurrence in doxorubicin-treated breast cancer patients with high eIF4E overexpression.

Byrnes KW, DeBenedetti A, Holm NT, Luke J, Nunez J, Chu QD, Meschonat C, Abreo F, Johnson LW, Li BD.

J Am Coll Surg. 2007 May;204(5):925-33; discussion 933-4.

PMID:
17481512
18.

Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.

Zhang W, Matrisian LM, Holmbeck K, Vick CC, Rosenthal EL.

BMC Cancer. 2006 Mar 6;6:52.

19.

Up-regulation of TLK1B by eIF4E overexpression predicts cancer recurrence in irradiated patients with breast cancer.

Wolfort R, de Benedetti A, Nuthalapaty S, Yu H, Chu QD, Li BD.

Surgery. 2006 Aug;140(2):161-9.

PMID:
16904965
20.

TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint.

Awate S, De Benedetti A.

BMC Mol Biol. 2016 Feb 9;17:3. doi: 10.1186/s12867-016-0056-x.

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