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Genome sequence of a multidrug-resistant Klebsiella pneumoniae ST78 with high colistin resistance isolated from a patient in India.

Paul M, Narendrakumar L, R Vasanthakumary A, Joseph I, Thomas S.

J Glob Antimicrob Resist. 2019 Apr 18;17:187-188. doi: 10.1016/j.jgar.2019.04.008. [Epub ahead of print]


Worldwide emergence of colistin resistance in Klebsiella pneumoniae from healthy humans and patients in Lao PDR, Thailand, Israel, Nigeria and France owing to inactivation of the PhoP/PhoQ regulator mgrB: an epidemiological and molecular study.

Olaitan AO, Diene SM, Kempf M, Berrazeg M, Bakour S, Gupta SK, Thongmalayvong B, Akkhavong K, Somphavong S, Paboriboune P, Chaisiri K, Komalamisra C, Adelowo OO, Fagade OE, Banjo OA, Oke AJ, Adler A, Assous MV, Morand S, Raoult D, Rolain JM.

Int J Antimicrob Agents. 2014 Dec;44(6):500-7. doi: 10.1016/j.ijantimicag.2014.07.020. Epub 2014 Sep 6.


Genomic Insights into Colistin-Resistant Klebsiella pneumoniae from a Tunisian Teaching Hospital.

Jaidane N, Bonnin RA, Mansour W, Girlich D, Creton E, Cotellon G, Chaouch C, Boujaafar N, Bouallegue O, Naas T.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01601-17. doi: 10.1128/AAC.01601-17. Print 2018 Feb.


Insertion element mediated mgrB disruption and presence of ISKpn28 in colistin-resistant Klebsiella pneumoniae isolates from Saudi Arabia.

Uz Zaman T, Albladi M, Siddique MI, Aljohani SM, Balkhy HH.

Infect Drug Resist. 2018 Aug 15;11:1183-1187. doi: 10.2147/IDR.S161146. eCollection 2018.


In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator.

Cannatelli A, D'Andrea MM, Giani T, Di Pilato V, Arena F, Ambretti S, Gaibani P, Rossolini GM.

Antimicrob Agents Chemother. 2013 Nov;57(11):5521-6. doi: 10.1128/AAC.01480-13. Epub 2013 Aug 26.


Hypermucoviscous polymyxin-resistant Klebsiella pneumoniae from Kolkata, India: Genomic and phenotypic analysis.

Bean DC, Agarwal A, Cherian BP, Wareham DW.

J Glob Antimicrob Resist. 2019 Feb 27;17:1-2. doi: 10.1016/j.jgar.2019.02.012. [Epub ahead of print]


Colistin resistance due to insertional inactivation of the mgrB in Klebsiella pneumoniae of clinical origin: First report from India.

Kumar A, Biswas L, Omgy N, Mohan K, Vinod V, Sajeev A, Nair P, Singh S, Biswas R.

Rev Esp Quimioter. 2018 Oct;31(5):406-410. Epub 2018 Sep 14.


The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae.

Poirel L, Jayol A, Bontron S, Villegas MV, Ozdamar M, Türkoglu S, Nordmann P.

J Antimicrob Chemother. 2015 Jan;70(1):75-80. doi: 10.1093/jac/dku323. Epub 2014 Sep 3.


Genomic Characterization of Colistin Heteroresistance in Klebsiella pneumoniae during a Nosocomial Outbreak.

Halaby T, Kucukkose E, Janssen AB, Rogers MR, Doorduijn DJ, van der Zanden AG, Al Naiemi N, Vandenbroucke-Grauls CM, van Schaik W.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6837-6843. doi: 10.1128/AAC.01344-16. Print 2016 Nov.


Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae Causing Bacteremia from India-A First Report.

Pragasam AK, Shankar C, Veeraraghavan B, Biswas I, Nabarro LE, Inbanathan FY, George B, Verghese S.

Front Microbiol. 2017 Jan 9;7:2135. doi: 10.3389/fmicb.2016.02135. eCollection 2016.


MgrB Alterations Mediate Colistin Resistance in Klebsiella pneumoniae Isolates from Iran.

Haeili M, Javani A, Moradi J, Jafari Z, Feizabadi MM, Babaei E.

Front Microbiol. 2017 Dec 18;8:2470. doi: 10.3389/fmicb.2017.02470. eCollection 2017.


Genomic analysis of the first isolate of KPC-2-producing Klebsiella pneumoniae from Uruguay.

Álvarez VE, Campos J, Galiana A, Borthagaray G, Centrón D, Márquez Villalba C.

J Glob Antimicrob Resist. 2018 Dec;15:109-110. doi: 10.1016/j.jgar.2018.09.001. Epub 2018 Sep 10.


Whole genome sequencing for the molecular characterization of carbapenem-resistant Klebsiella pneumoniae strains isolated at the Italian ASST Fatebenefratelli Sacco Hospital, 2012-2014.

Rimoldi SG, Gentile B, Pagani C, Di Gregorio A, Anselmo A, Palozzi AM, Fortunato A, Pittiglio V, Ridolfo AL, Gismondo MR, Rizzardini G, Lista F.

BMC Infect Dis. 2017 Oct 10;17(1):666. doi: 10.1186/s12879-017-2760-7.


Molecular Epidemiology and Virulence Profiles of Colistin-Resistant Klebsiella pneumoniae Blood Isolates From the Hospital Agency "Ospedale dei Colli," Naples, Italy.

Esposito EP, Cervoni M, Bernardo M, Crivaro V, Cuccurullo S, Imperi F, Zarrilli R.

Front Microbiol. 2018 Jul 16;9:1463. doi: 10.3389/fmicb.2018.01463. eCollection 2018.


Multidrug Resistance Mechanisms of Carbapenem Resistant Klebsiella pneumoniae Strains Isolated in Chongqing, China.

Yan J, Pu S, Jia X, Xu X, Yang S, Shi J, Sun S, Zhang L.

Ann Lab Med. 2017 Sep;37(5):398-407. doi: 10.3343/alm.2017.37.5.398.


Draft genome sequence of a tigecycline-resistant KPC-2-producing Klebsiella pneumoniae ST15 clinical isolate from China.

Xu J, Gao M, Hong Y, He F.

J Glob Antimicrob Resist. 2017 Dec;11:156-158. doi: 10.1016/j.jgar.2017.10.017. Epub 2017 Oct 31.


MgrB inactivation is a common mechanism of colistin resistance in KPC-producing Klebsiella pneumoniae of clinical origin.

Cannatelli A, Giani T, D'Andrea MM, Di Pilato V, Arena F, Conte V, Tryfinopoulou K, Vatopoulos A, Rossolini GM; COLGRIT Study Group.

Antimicrob Agents Chemother. 2014 Oct;58(10):5696-703. doi: 10.1128/AAC.03110-14. Epub 2014 Jul 14.


Modulation of mgrB gene expression as a source of colistin resistance in Klebsiella oxytoca.

Jayol A, Poirel L, Villegas MV, Nordmann P.

Int J Antimicrob Agents. 2015 Jul;46(1):108-10. doi: 10.1016/j.ijantimicag.2015.02.015. Epub 2015 Mar 28.


Tracking microevolution events among ST11 carbapenemase-producing hypervirulent Klebsiella pneumoniae outbreak strains.

Dong N, Yang X, Zhang R, Chan EW, Chen S.

Emerg Microbes Infect. 2018 Aug 12;7(1):146. doi: 10.1038/s41426-018-0146-6.


Resistome of carbapenem- and colistin-resistant Klebsiella pneumoniae clinical isolates.

Lomonaco S, Crawford MA, Lascols C, Timme RE, Anderson K, Hodge DR, Fisher DJ, Pillai SP, Morse SA, Khan E, Hughes MA, Allard MW, Sharma SK.

PLoS One. 2018 Jun 8;13(6):e0198526. doi: 10.1371/journal.pone.0198526. eCollection 2018.

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