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Items: 1 to 20 of 99

1.

Yeast Models for the Study of Amyloid-Associated Disorders and Development of Future Therapy.

Rencus-Lazar S, DeRowe Y, Adsi H, Gazit E, Laor D.

Front Mol Biosci. 2019 Mar 22;6:15. doi: 10.3389/fmolb.2019.00015. eCollection 2019. Review.

2.

Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation.

Laor D, Sade D, Shaham-Niv S, Zaguri D, Gartner M, Basavalingappa V, Raveh A, Pichinuk E, Engel H, Iwasaki K, Yamamoto T, Noothalapati H, Gazit E.

Nat Commun. 2019 Jan 8;10(1):62. doi: 10.1038/s41467-018-07966-5.

3.

Metabolite amyloids: a new paradigm for inborn error of metabolism disorders.

Gazit E.

J Inherit Metab Dis. 2016 Jul;39(4):483-8. doi: 10.1007/s10545-016-9946-9. Epub 2016 Jun 6.

PMID:
27271695
4.

Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations.

Sade D, Shaham-Niv S, Arnon ZA, Tavassoly O, Gazit E.

Open Biol. 2018 Jan;8(1). pii: 170229. doi: 10.1098/rsob.170229. Review.

5.

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases.

Outeiro TF, Giorgini F.

Biotechnol J. 2006 Mar;1(3):258-69. Review.

PMID:
16897706
6.

Purification of hsp104, a protein disaggregase.

Sweeny EA, DeSantis ME, Shorter J.

J Vis Exp. 2011 Sep 30;(55). pii: 3190. doi: 10.3791/3190.

7.

Screening for amyloid proteins in the yeast proteome.

Ryzhova TA, Sopova JV, Zadorsky SP, Siniukova VA, Sergeeva AV, Galkina SA, Nizhnikov AA, Shenfeld AA, Volkov KV, Galkin AP.

Curr Genet. 2018 Apr;64(2):469-478. doi: 10.1007/s00294-017-0759-7. Epub 2017 Oct 11.

PMID:
29027580
8.

Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.

Meredith SC.

Ann N Y Acad Sci. 2005 Dec;1066:181-221. Review.

PMID:
16533927
9.

Molecular genetics approaches in yeast to study amyloid diseases.

Outeiro TF, Muchowski PJ.

J Mol Neurosci. 2004;23(1-2):49-60. Review.

PMID:
15126692
10.

Inhibition of amyloid oligomerization into different supramolecular architectures by small molecules: mechanistic insights and design rules.

Brahmachari S, Paul A, Segal D, Gazit E.

Future Med Chem. 2017 May;9(8):797-810. doi: 10.4155/fmc-2017-0026. Epub 2017 May 9. Review.

PMID:
28485623
11.

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease.

Glabe CG.

Neurobiol Aging. 2006 Apr;27(4):570-5. Epub 2006 Feb 14. Review.

PMID:
16481071
12.

Q-Rich Yeast Prion [PSI+] Accelerates Aggregation of Transthyretin, a Non-Q-Rich Human Protein.

Verma M, Girdhar A, Patel B, Ganguly NK, Kukreti R, Taneja V.

Front Mol Neurosci. 2018 Mar 13;11:75. doi: 10.3389/fnmol.2018.00075. eCollection 2018.

13.

Elucidating the Structures of Amyloid Oligomers with Macrocyclic β-Hairpin Peptides: Insights into Alzheimer's Disease and Other Amyloid Diseases.

Kreutzer AG, Nowick JS.

Acc Chem Res. 2018 Mar 20;51(3):706-718. doi: 10.1021/acs.accounts.7b00554. Epub 2018 Mar 6. Review.

14.

[Neurodegenerative amyloidoses: the yeast model].

Vishnevskaia AB, Kushnirov VV, Ter-Avanesian MD.

Mol Biol (Mosk). 2007 Mar-Apr;41(2):346-54. Review. Russian.

PMID:
17514901
15.

Toxic species in amyloid disorders: Oligomers or mature fibrils.

Verma M, Vats A, Taneja V.

Ann Indian Acad Neurol. 2015 Apr-Jun;18(2):138-45. doi: 10.4103/0972-2327.144284. Review.

17.

Yeast models for amyloid disease.

Panaretou B, Jones GW.

Essays Biochem. 2014;56:85-97. doi: 10.1042/bse0560085.

PMID:
25131588
18.

Intrinsic Fluorescence of Metabolite Amyloids Allows Label-Free Monitoring of Their Formation and Dynamics in Live Cells.

Shaham-Niv S, Arnon ZA, Sade D, Lichtenstein A, Shirshin EA, Kolusheva S, Gazit E.

Angew Chem Int Ed Engl. 2018 Sep 17;57(38):12444-12447. doi: 10.1002/anie.201806565. Epub 2018 Aug 28.

PMID:
30088843
19.

Conformation-dependent scFv antibodies specifically recognize the oligomers assembled from various amyloids and show colocalization of amyloid fibrils with oligomers in patients with amyloidoses.

Zhang X, Sun XX, Xue D, Liu DG, Hu XY, Zhao M, Yang SG, Yang Y, Xia YJ, Wang Y, Liu RT.

Biochim Biophys Acta. 2011 Dec;1814(12):1703-12. doi: 10.1016/j.bbapap.2011.09.005. Epub 2011 Sep 25.

PMID:
21979582
20.

Contribution of yeast models to neurodegeneration research.

Pereira C, Bessa C, Soares J, Leão M, Saraiva L.

J Biomed Biotechnol. 2012;2012:941232. doi: 10.1155/2012/941232. Epub 2012 Jul 15. Review.

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