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Items: 1 to 20 of 101

1.

Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons.

Ruiz-Calvo A, Bajo-Grañeras R, Maroto IB, Zian D, Grabner GF, García-Taboada E, Resel E, Zechner R, Zimmermann R, Ortega-Gutiérrez S, Galve-Roperh I, Bellocchio L, Guzmán M.

Neuropharmacology. 2019 May 15;150:134-144. doi: 10.1016/j.neuropharm.2019.03.027. Epub 2019 Mar 23.

PMID:
30914306
2.

Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.

Zhang H, Li Q, Graham RK, Slow E, Hayden MR, Bezprozvanny I.

Neurobiol Dis. 2008 Jul;31(1):80-8. doi: 10.1016/j.nbd.2008.03.010. Epub 2008 Apr 16.

3.

Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice.

Naydenov AV, Sepers MD, Swinney K, Raymond LA, Palmiter RD, Stella N.

Neurobiol Dis. 2014 Nov;71:140-50. doi: 10.1016/j.nbd.2014.08.009. Epub 2014 Aug 15.

4.

Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment.

McMeekin LJ, Li Y, Fox SN, Rowe GC, Crossman DK, Day JJ, Li Y, Detloff PJ, Cowell RM.

J Neurosci. 2018 Mar 28;38(13):3273-3286. doi: 10.1523/JNEUROSCI.0848-17.2018. Epub 2018 Feb 28.

5.

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation.

Grabner GF, Eichmann TO, Wagner B, Gao Y, Farzi A, Taschler U, Radner FP, Schweiger M, Lass A, Holzer P, Zinser E, Tschöp MH, Yi CX, Zimmermann R.

J Biol Chem. 2016 Jan 8;291(2):913-23. doi: 10.1074/jbc.M115.683615. Epub 2015 Nov 12.

6.

Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors.

Ruiz-Calvo A, Maroto IB, Bajo-Grañeras R, Chiarlone A, Gaudioso Á, Ferrero JJ, Resel E, Sánchez-Prieto J, Rodríguez-Navarro JA, Marsicano G, Galve-Roperh I, Bellocchio L, Guzmán M.

Cereb Cortex. 2018 Jan 1;28(1):307-322. doi: 10.1093/cercor/bhx285.

PMID:
29121220
7.

Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.

Wu J, Ryskamp DA, Liang X, Egorova P, Zakharova O, Hung G, Bezprozvanny I.

J Neurosci. 2016 Jan 6;36(1):125-41. doi: 10.1523/JNEUROSCI.1038-15.2016.

8.

Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol.

Petrenko AB, Yamazaki M, Sakimura K, Kano M, Baba H.

Behav Brain Res. 2014 Sep 1;271:51-8. doi: 10.1016/j.bbr.2014.05.063. Epub 2014 Jun 4.

PMID:
24906199
10.

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

Palazuelos J, Aguado T, Pazos MR, Julien B, Carrasco C, Resel E, Sagredo O, Benito C, Romero J, Azcoitia I, Fernández-Ruiz J, Guzmán M, Galve-Roperh I.

Brain. 2009 Nov;132(Pt 11):3152-64. doi: 10.1093/brain/awp239. Epub 2009 Oct 5.

PMID:
19805493
11.

Genetic inactivation and prolonged pharmacologic inhibition of monoacylglycerol lipase have opposite effects on anesthetic sensitivity to propofol.

Petrenko AB, Yamazaki M, Sakimura K, Kano M, Baba H.

Eur J Pharmacol. 2015 Oct 15;765:268-73. doi: 10.1016/j.ejphar.2015.08.048. Epub 2015 Aug 28.

PMID:
26318148
12.

Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model.

Sepers MD, Smith-Dijak A, LeDue J, Kolodziejczyk K, Mackie K, Raymond LA.

J Neurosci. 2018 Jan 17;38(3):544-554. doi: 10.1523/JNEUROSCI.1739-17.2017. Epub 2017 Nov 30.

13.

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.

Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, Ruiz C, Sendtner M, Lucas JJ, de Yébenes JG, Marsicano G, Monory K, Lutz B, Romero J, Alberch J, Ginés S, Kraus J, Fernández-Ruiz J, Galve-Roperh I, Guzmán M.

Brain. 2011 Jan;134(Pt 1):119-36. doi: 10.1093/brain/awq278. Epub 2010 Oct 7.

PMID:
20929960
14.

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.

Bradford J, Shin JY, Roberts M, Wang CE, Li XJ, Li S.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22480-5. doi: 10.1073/pnas.0911503106. Epub 2009 Dec 11.

15.

Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus.

Gutiérrez-Rodríguez A, Bonilla-Del Río I, Puente N, Gómez-Urquijo SM, Fontaine CJ, Egaña-Huguet J, Elezgarai I, Ruehle S, Lutz B, Robin LM, Soria-Gómez E, Bellocchio L, Padwal JD, van der Stelt M, Mendizabal-Zubiaga J, Reguero L, Ramos A, Gerrikagoitia I, Marsicano G, Grandes P.

Glia. 2018 Jul;66(7):1417-1431. doi: 10.1002/glia.23314. Epub 2018 Feb 26.

PMID:
29480581
16.

Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes.

Bosier B, Bellocchio L, Metna-Laurent M, Soria-Gomez E, Matias I, Hebert-Chatelain E, Cannich A, Maitre M, Leste-Lasserre T, Cardinal P, Mendizabal-Zubiaga J, Canduela MJ, Reguero L, Hermans E, Grandes P, Cota D, Marsicano G.

Mol Metab. 2013 Aug 9;2(4):393-404. doi: 10.1016/j.molmet.2013.08.001. eCollection 2013.

17.

Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.

Kovalenko M, Dragileva E, St Claire J, Gillis T, Guide JR, New J, Dong H, Kucherlapati R, Kucherlapati MH, Ehrlich ME, Lee JM, Wheeler VC.

PLoS One. 2012;7(9):e44273. doi: 10.1371/journal.pone.0044273. Epub 2012 Sep 7.

19.

Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.

Brown TB, Bogush AI, Ehrlich ME.

Hum Mol Genet. 2008 Oct 15;17(20):3095-104. doi: 10.1093/hmg/ddn206. Epub 2008 Jul 16.

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