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Items: 1 to 20 of 101

1.

Spermine on Endothelial Extracellular Vesicles Mediates Smoking-Induced Pulmonary Hypertension Partially Through Calcium-Sensing Receptor.

Zhu L, Xiao R, Zhang X, Lang Y, Liu F, Yu Z, Zhang J, Su Y, Lu Y, Wang T, Luo S, Wang J, Liu ML, Dupuis J, Jing ZC, Li T, Xiong W, Hu Q.

Arterioscler Thromb Vasc Biol. 2019 Jan 10:ATVBAHA118312280. doi: 10.1161/ATVBAHA.118.312280. [Epub ahead of print]

PMID:
30626206
2.

Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction.

Zhang J, Zhou J, Cai L, Lu Y, Wang T, Zhu L, Hu Q.

Antioxid Redox Signal. 2012 Aug 1;17(3):471-84. doi: 10.1089/ars.2011.4168. Epub 2012 Jan 25.

PMID:
22098336
3.

Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension.

Yamamura A, Guo Q, Yamamura H, Zimnicka AM, Pohl NM, Smith KA, Fernandez RA, Zeifman A, Makino A, Dong H, Yuan JX.

Circ Res. 2012 Aug 3;111(4):469-81. doi: 10.1161/CIRCRESAHA.112.266361. Epub 2012 Jun 22.

4.

Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor.

Xiao R, Su Y, Feng T, Sun M, Liu B, Zhang J, Lu Y, Li J, Wang T, Zhu L, Hu Q.

J Am Heart Assoc. 2017 Mar 22;6(4). pii: e004865. doi: 10.1161/JAHA.116.004865.

5.

Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension.

Zeng X, Zhu L, Xiao R, Liu B, Sun M, Liu F, Hao Q, Lu Y, Zhang J, Li J, Wang T, Wei X, Hu Q.

Hypertension. 2017 May;69(5):844-854. doi: 10.1161/HYPERTENSIONAHA.116.08743. Epub 2017 Mar 27.

PMID:
28348014
6.

Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries.

Peng X, Li HX, Shao HJ, Li GW, Sun J, Xi YH, Li HZ, Wang XY, Wang LN, Bai SZ, Zhang WH, Zhang L, Yang GD, Wu LY, Wang R, Xu CQ.

Mol Cell Biochem. 2014 Nov;396(1-2):87-98. doi: 10.1007/s11010-014-2145-9. Epub 2014 Jul 26.

PMID:
25063217
7.
8.

Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig.

Ferrer E, Peinado VI, Díez M, Carrasco JL, Musri MM, Martínez A, Rodríguez-Roisin R, Barberà JA.

Respir Res. 2009 Aug 14;10:76. doi: 10.1186/1465-9921-10-76.

9.

Notch activation of Ca2+-sensing receptor mediates hypoxia-induced pulmonary hypertension.

Guo Q, Xu H, Yang X, Zhao D, Liu S, Sun X, Huang JA.

Hypertens Res. 2017 Feb;40(2):117-129. doi: 10.1038/hr.2016.118. Epub 2016 Sep 1.

PMID:
27581537
10.

Mitochondria-regulated formation of endothelium-derived extracellular vesicles shifts the mediator of flow-induced vasodilation.

Freed JK, Durand MJ, Hoffmann BR, Densmore JC, Greene AS, Gutterman DD.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1096-H1104. doi: 10.1152/ajpheart.00680.2016. Epub 2017 Feb 17.

11.

Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)] by activating Ca(2+)-sensing receptors in pulmonary arterial smooth muscle cells.

Yamamura A, Yamamura H, Guo Q, Zimnicka AM, Wan J, Ko EA, Smith KA, Pohl NM, Song S, Zeifman A, Makino A, Yuan JX.

Circ Res. 2013 Feb 15;112(4):640-50. doi: 10.1161/CIRCRESAHA.113.300897. Epub 2013 Jan 8.

12.

The calcium-sensing receptor mediates hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways.

Li GW, Xing WJ, Bai SZ, Hao JH, Guo J, Li HZ, Li HX, Zhang WH, Yang BF, Wu LY, Wang R, Yang GD, Xu CQ.

Basic Clin Pharmacol Toxicol. 2011 Mar;108(3):185-93. doi: 10.1111/j.1742-7843.2010.00639.x. Epub 2010 Nov 12.

13.

Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.

Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey Z, Black SM, Garcia JG, Makino A, Yuan JX.

Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L846-59. doi: 10.1152/ajplung.00050.2016. Epub 2016 Mar 11.

14.

Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: possible involvement of angiotensin-converting enzyme-2.

Han SX, He GM, Wang T, Chen L, Ning YY, Luo F, An J, Yang T, Dong JJ, Liao ZL, Xu D, Wen FQ.

Toxicol Appl Pharmacol. 2010 May 15;245(1):100-7. doi: 10.1016/j.taap.2010.02.009. Epub 2010 Feb 21.

PMID:
20178811
15.

Extracellular calcium-sensing receptor is expressed in rat hepatocytes. coupling to intracellular calcium mobilization and stimulation of bile flow.

Canaff L, Petit JL, Kisiel M, Watson PH, Gascon-Barré M, Hendy GN.

J Biol Chem. 2001 Feb 9;276(6):4070-9. Epub 2000 Nov 8.

16.

Calcium sensing receptor regulating smooth muscle cells proliferation through initiating cystathionine-gamma-lyase/hydrogen sulfide pathway in diabetic rat.

Zhong X, Wang Y, Wu J, Sun A, Yang F, Zheng D, Li T, Dong S, Zhao Y, Yang G, Xu C, Sun D, Lu F, Zhang W.

Cell Physiol Biochem. 2015;35(4):1582-98. doi: 10.1159/000373973. Epub 2015 Mar 18.

17.

[Cigarette smoke exposure induced pulmonary artery pressure increase through inhibiting Kv1.5 and Kv2.1 mRNA expression in rat pulmonary artery smooth muscles].

Lin CY, Wan LM, Chen YQ, Ou HT, Zhao L, Liang YT, Ma R, Lu WJ, Wang J.

Zhonghua Jie He He Hu Xi Za Zhi. 2012 Sep;35(9):695-9. Chinese.

PMID:
23158075
18.

Exogenous spermine inhibits the proliferation of human pulmonary artery smooth muscle cells caused by chemically-induced hypoxia via the suppression of the ERK1/2- and PI3K/AKT-associated pathways.

Wei C, Li HZ, Wang YH, Peng X, Shao HJ, Li HX, Bai SZ, Lu XX, Wu LY, Wang R, Xu CQ.

Int J Mol Med. 2016 Jan;37(1):39-46. doi: 10.3892/ijmm.2015.2408. Epub 2015 Nov 11.

19.

Calcium-Sensing Receptor Regulates Cytosolic [Ca 2+ ] and Plays a Major Role in the Development of Pulmonary Hypertension.

Smith KA, Ayon RJ, Tang H, Makino A, Yuan JX.

Front Physiol. 2016 Nov 4;7:517. eCollection 2016. Review.

20.

Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: the role of calpain.

Su Y, Cao W, Han Z, Block ER.

Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L794-800. Epub 2004 Jun 4.

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