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Items: 1 to 20 of 98


Effect of Increasing Age on Brain Dysfunction in Cirrhosis.

Liu R, Ahluwalia V, Kang JD, Ghosh SS, Zhou H, Li Y, Zhao D, Gurley E, Li X, White MB, Fagan A, Lippman HR, Wade JB, Hylemon PB, Bajaj JS.

Hepatol Commun. 2018 Nov 30;3(1):63-73. doi: 10.1002/hep4.1286. eCollection 2019 Jan.


Evaluation of cognitivity, proinflammatory cytokines, and brain magnetic resonance imaging in minimal hepatic encephalopathy induced by cirrhosis and extrahepatic portal vein obstruction.

Yadav SK, Goel A, Saraswat VA, Thomas MA, Wang E, Marincola FM, Haris M, Gupta RK.

J Gastroenterol Hepatol. 2016 Dec;31(12):1986-1994. doi: 10.1111/jgh.13427.


Brain inflammation induces post-synaptic changes during early synapse formation in adult-born hippocampal neurons.

Chugh D, Nilsson P, Afjei SA, Bakochi A, Ekdahl CT.

Exp Neurol. 2013 Dec;250:176-88. doi: 10.1016/j.expneurol.2013.09.005. Epub 2013 Sep 15.


Differential impact of hyponatremia and hepatic encephalopathy on health-related quality of life and brain metabolite abnormalities in cirrhosis.

Ahluwalia V, Wade JB, Thacker L, Kraft KA, Sterling RK, Stravitz RT, Fuchs M, Bouneva I, Puri P, Luketic V, Sanyal AJ, Gilles H, Heuman DM, Bajaj JS.

J Hepatol. 2013 Sep;59(3):467-73. doi: 10.1016/j.jhep.2013.04.023. Epub 2013 May 7.


Abnormal functional connectivity within the default mode network in patients with HBV-related cirrhosis without hepatic encephalopathy revealed by resting-state functional MRI.

Qi R, Zhang LJ, Xu Q, Liang X, Luo S, Zhang Z, Huang W, Zheng L, Lu GM.

Brain Res. 2014 Aug 12;1576:73-80. doi: 10.1016/j.brainres.2014.05.044. Epub 2014 Jun 5.


Elderly patients have an altered gut-brain axis regardless of the presence of cirrhosis.

Bajaj JS, Ahluwalia V, Steinberg JL, Hobgood S, Boling PA, Godschalk M, Habib S, White MB, Fagan A, Gavis EA, Ganapathy D, Hylemon PB, Stewart KE, Keradman R, Liu EJ, Wang J, Gillevet PM, Sikaroodi M, Moeller FG, Wade JB.

Sci Rep. 2016 Dec 6;6:38481. doi: 10.1038/srep38481.


Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy.

Serantes R, Arnalich F, Figueroa M, Salinas M, Andrés-Mateos E, Codoceo R, Renart J, Matute C, Cavada C, Cuadrado A, Montiel C.

J Biol Chem. 2006 May 26;281(21):14632-43. Epub 2006 Mar 27.


Microglia activation in hepatic encephalopathy in rats and humans.

Zemtsova I, Görg B, Keitel V, Bidmon HJ, Schrör K, Häussinger D.

Hepatology. 2011 Jul;54(1):204-15. doi: 10.1002/hep.24326.


Resting-state functional connectivity abnormalities correlate with psychometric hepatic encephalopathy score in cirrhosis.

Chen HJ, Jiang LF, Sun T, Liu J, Chen QF, Shi HB.

Eur J Radiol. 2015 Nov;84(11):2287-95. doi: 10.1016/j.ejrad.2015.08.005. Epub 2015 Aug 18.


Gut microbiota drive the development of neuroinflammatory response in cirrhosis in mice.

Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, Lippman HR, Sikaroodi M, Brown RR, Bajaj JS.

Hepatology. 2016 Oct;64(4):1232-48. doi: 10.1002/hep.28696. Epub 2016 Jul 29.


Liver transplantation significantly improves global functioning and cerebral processing.

Ahluwalia V, Wade JB, White MB, Gilles HS, Heuman DM, Fuchs M, Gavis EA, Fagan A, Tinsley F, Ganapathy D, Thacker LR, Sterling RK, Stravitz RT, Puri P, Sanyal AJ, Siddiqui MS, Matherly S, Luketic V, Steinberg J, Moeller FG, Bajaj JS.

Liver Transpl. 2016 Oct;22(10):1379-90. doi: 10.1002/lt.24498.


Resveratrol Restores Neuronal Tight Junction Proteins Through Correction of Ammonia and Inflammation in CCl4-Induced Cirrhotic Mice.

Vairappan B, Sundhar M, Srinivas BH.

Mol Neurobiol. 2018 Oct 30. doi: 10.1007/s12035-018-1389-x. [Epub ahead of print]


Enhancement of functional connectivity, working memory and inhibitory control on multi-modal brain MR imaging with Rifaximin in Cirrhosis: implications for the gut-liver-brain axis.

Ahluwalia V, Wade JB, Heuman DM, Hammeke TA, Sanyal AJ, Sterling RK, Stravitz RT, Luketic V, Siddiqui MS, Puri P, Fuchs M, Lennon MJ, Kraft KA, Gilles H, White MB, Noble NA, Bajaj JS.

Metab Brain Dis. 2014 Dec;29(4):1017-25. doi: 10.1007/s11011-014-9507-6. Epub 2014 Mar 4.


Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis.

Bajaj JS, Ahluwalia V, Wade JB, Sanyal AJ, White MB, Noble NA, Monteith P, Fuchs M, Sterling RK, Luketic V, Bouneva I, Stravitz RT, Puri P, Kraft KA, Gilles H, Heuman DM.

J Hepatol. 2013 Jan;58(1):38-44. doi: 10.1016/j.jhep.2012.08.005. Epub 2012 Aug 11.


Functional brain network changes associated with clinical and biochemical measures of the severity of hepatic encephalopathy.

Jao T, Schröter M, Chen CL, Cheng YF, Lo CY, Chou KH, Patel AX, Lin WC, Lin CP, Bullmore ET.

Neuroimage. 2015 Nov 15;122:332-44. doi: 10.1016/j.neuroimage.2015.07.068. Epub 2015 Jul 31.


Characterisation of temporal microglia and astrocyte immune responses in bile duct-ligated rat models of cirrhosis.

Wright GA, Sharifi Y, Newman TA, Davies N, Vairappan B, Perry HV, Jalan R.

Liver Int. 2014 Sep;34(8):1184-91. doi: 10.1111/liv.12481. Epub 2014 Apr 9.


Is there an association between peripheral immune markers and structural/functional neuroimaging findings?

Frodl T, Amico F.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jan 3;48:295-303. doi: 10.1016/j.pnpbp.2012.12.013. Epub 2013 Jan 11. Review.


Repetitive transcranial magnetic stimulation (rTMS) influences spatial cognition and modulates hippocampal structural synaptic plasticity in aging mice.

Ma J, Zhang Z, Kang L, Geng D, Wang Y, Wang M, Cui H.

Exp Gerontol. 2014 Oct;58:256-68. doi: 10.1016/j.exger.2014.08.011. Epub 2014 Aug 27.


Abnormalities of voxel-based whole-brain functional connectivity patterns predict the progression of hepatic encephalopathy.

Zhang G, Cheng Y, Liu B.

Brain Imaging Behav. 2017 Jun;11(3):784-796. doi: 10.1007/s11682-016-9553-2.


Impaired Gut-Liver-Brain Axis in Patients with Cirrhosis.

Ahluwalia V, Betrapally NS, Hylemon PB, White MB, Gillevet PM, Unser AB, Fagan A, Daita K, Heuman DM, Zhou H, Sikaroodi M, Bajaj JS.

Sci Rep. 2016 May 26;6:26800. doi: 10.1038/srep26800.

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