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Items: 1 to 20 of 101

1.

Consistent success in life-supporting porcine cardiac xenotransplantation.

Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM.

Nature. 2018 Dec;564(7736):430-433. doi: 10.1038/s41586-018-0765-z. Epub 2018 Dec 5.

PMID:
30518863
2.

Pig-to-baboon heterotopic heart transplantation--exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens.

Iwase H, Ekser B, Satyananda V, Bhama J, Hara H, Ezzelarab M, Klein E, Wagner R, Long C, Thacker J, Li J, Zhou H, Jiang M, Nagaraju S, Zhou H, Veroux M, Bajona P, Wijkstrom M, Wang Y, Phelps C, Klymiuk N, Wolf E, Ayares D, Cooper DK.

Xenotransplantation. 2015 May-Jun;22(3):211-20. doi: 10.1111/xen.12167. Epub 2015 Apr 3.

3.

Xenotransplantation of solid organs in the pig-to-primate model.

Ekser B, Rigotti P, Gridelli B, Cooper DK.

Transpl Immunol. 2009 Jun;21(2):87-92. doi: 10.1016/j.trim.2008.10.005. Epub 2008 Oct 26. Review.

PMID:
18955143
4.

Initial study of α1,3-galactosyltransferase gene-knockout/CD46 pig full-thickness corneal xenografts in rhesus monkeys.

Dong X, Hara H, Wang Y, Wang L, Zhang Y, Cooper DK, Dai Y, Pan Z.

Xenotransplantation. 2017 Jan;24(1). doi: 10.1111/xen.12282. Epub 2017 Jan 5.

PMID:
28054735
5.

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation.

Mohiuddin MM, Singh AK, Corcoran PC, Hoyt RF, Thomas ML 3rd, Ayares D, Horvath KA.

J Thorac Cardiovasc Surg. 2014 Sep;148(3):1106-13; discussion 1113-4. doi: 10.1016/j.jtcvs.2014.06.002. Epub 2014 Jun 6.

6.

IG-therasorb immunoapheresis in orthotopic xenotransplantation of baboons with landrace pig hearts.

Brenner P, Reichenspurner H, Schmoeckel M, Wimmer C, Rucker A, Eder V, Meiser B, Hinz M, Felbinger T, Müller-Höcker J, Hammer C, Reichart B.

Transplantation. 2000 Jan 27;69(2):208-14.

PMID:
10670628
7.

Prevention of hyperacute xenograft rejection in orthotopic xenotransplantation of pig hearts into baboons using immunoadsorption of antibodies and complement factors.

Brenner P, Reichenspurner H, Schmoeckel M, Wimmer C, Rucker A, Eder V, Meiser B, Hinz M, Felbinger T, Hammer C, Reichart B.

Transpl Int. 2000;13 Suppl 1:S508-17.

PMID:
11112063
8.
10.

CD4+CD25Hi FoxP3+ regulatory T cells in long-term cardiac xenotransplantation.

Singh AK, Chan JL, Seavey CN, Corcoran PC, Hoyt RF Jr, Lewis BGT, Thomas ML, Ayares DL, Horvath KA, Mohiuddin MM.

Xenotransplantation. 2018 Mar;25(2):e12379. doi: 10.1111/xen.12379. Epub 2017 Dec 17.

PMID:
29250828
11.

Cardiac xenotransplantation: progress toward the clinic.

McGregor CG, Teotia SS, Byrne GW, Michaels MG, Risdahl JM, Schirmer JM, Tazelaar HD, Walker RC, Logan JS.

Transplantation. 2004 Dec 15;78(11):1569-75.

PMID:
15591943
12.

Cytokine profiles in Tibetan macaques following α-1,3-galactosyltransferase-knockout pig liver xenotransplantation.

Zhang Z, Li X, Zhang H, Zhang X, Chen H, Pan D, Ji H, Zhou L, Ling J, Zhou J, Yue S, Wang D, Yang Z, Tao K, Dou K.

Xenotransplantation. 2017 Sep;24(5). doi: 10.1111/xen.12321. Epub 2017 Jul 17.

PMID:
28714241
13.

Cardiac xenotransplantation: recent preclinical progress with 3-month median survival.

McGregor CG, Davies WR, Oi K, Teotia SS, Schirmer JM, Risdahl JM, Tazelaar HD, Kremers WK, Walker RC, Byrne GW, Logan JS.

J Thorac Cardiovasc Surg. 2005 Sep;130(3):844-51.

14.

Life supporting function for over one month of a transgenic porcine heart in a baboon.

Vial CM, Ostlie DJ, Bhatti FN, Cozzi E, Goddard M, Chavez GP, Wallwork J, White DJ, Dunning JJ.

J Heart Lung Transplant. 2000 Feb;19(2):224-9.

PMID:
10703701
15.

Histopathology of xenografts in pig to non-human primate discordant xenotransplantation.

Shimizu A, Yamada K.

Clin Transplant. 2010 Jul;24 Suppl 22:11-5. doi: 10.1111/j.1399-0012.2010.01270.x. Review.

PMID:
20590687
16.

Microcirculatory alterations after orthotopic pig-to-baboon heart transplantation.

Bauer A, Renz V, Baschnegger H, Abicht JM, Beiras-Fernandez A, Brenner P, Thein E, Schmoeckel M, Reichart B, Christ F.

Xenotransplantation. 2011 Jul-Aug;18(4):232-8. doi: 10.1111/j.1399-3089.2011.00645.x.

PMID:
21848540
17.

Encouraging experience using multi-transgenic xenografts in a pig-to-baboon cardiac xenotransplantation model.

Chan JL, Singh AK, Corcoran PC, Thomas ML, Lewis BG, Ayares DL, Vaught T, Horvath KA, Mohiuddin MM.

Xenotransplantation. 2017 Nov;24(6). doi: 10.1111/xen.12330. Epub 2017 Sep 22.

PMID:
28940570
18.

Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein.

Azimzadeh AM, Kelishadi SS, Ezzelarab MB, Singh AK, Stoddard T, Iwase H, Zhang T, Burdorf L, Sievert E, Avon C, Cheng X, Ayares D, Horvath KA, Corcoran PC, Mohiuddin MM, Barth RN, Cooper DK, Pierson RN 3rd.

Xenotransplantation. 2015 Jul-Aug;22(4):310-6. doi: 10.1111/xen.12176. Epub 2015 Jul 14.

19.

Report of the Xenotransplantation Advisory Committee of the International Society for Heart and Lung Transplantation: the present status of xenotransplantation and its potential role in the treatment of end-stage cardiac and pulmonary diseases.

Cooper DK, Keogh AM, Brink J, Corris PA, Klepetko W, Pierson RN, Schmoeckel M, Shirakura R, Warner Stevenson L; Xenotransplantation Advisory Committee of the International Society for Heart and Lung Transplantation.

J Heart Lung Transplant. 2000 Dec;19(12):1125-65. Review.

PMID:
11124485
20.

Systemic inflammation in xenograft recipients precedes activation of coagulation.

Ezzelarab MB, Ekser B, Azimzadeh A, Lin CC, Zhao Y, Rodriguez R, Echeverri GJ, Iwase H, Long C, Hara H, Ayares D, Pierson RN, Thomson AW, Cooper DK.

Xenotransplantation. 2015 Jan-Feb;22(1):32-47. doi: 10.1111/xen.12133. Epub 2014 Sep 11.

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