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Items: 1 to 20 of 100

1.

Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury.

Zeng S, Wen KK, Workalemahu G, Sohn EH, Wu M, Chirco KR, Flamme-Wiese MJ, Liu X, Stone EM, Tucker BA, Mullins RF.

Sci Rep. 2018 Sep 6;8(1):13387. doi: 10.1038/s41598-018-31846-z.

2.

Senescence Increases Choroidal Endothelial Stiffness and Susceptibility to Complement Injury: Implications for Choriocapillaris Loss in AMD.

Cabrera AP, Bhaskaran A, Xu J, Yang X, Scott HA, Mohideen U, Ghosh K.

Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):5910-5918. doi: 10.1167/iovs.16-19727.

3.

Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration.

Zeng S, Whitmore SS, Sohn EH, Riker MJ, Wiley LA, Scheetz TE, Stone EM, Tucker BA, Mullins RF.

J Pathol. 2016 Feb;238(3):446-56. doi: 10.1002/path.4669. Epub 2015 Dec 24.

4.

The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.

Mullins RF, Schoo DP, Sohn EH, Flamme-Wiese MJ, Workamelahu G, Johnston RM, Wang K, Tucker BA, Stone EM.

Am J Pathol. 2014 Nov;184(11):3142-53. doi: 10.1016/j.ajpath.2014.07.017. Epub 2014 Sep 7.

5.

Topical application of PPADS inhibits complement activation and choroidal neovascularization in a model of age-related macular degeneration.

Birke K, Lipo E, Birke MT, Kumar-Singh R.

PLoS One. 2013 Oct 9;8(10):e76766. doi: 10.1371/journal.pone.0076766. eCollection 2013.

6.

Structural and molecular changes in the aging choroid: implications for age-related macular degeneration.

Chirco KR, Sohn EH, Stone EM, Tucker BA, Mullins RF.

Eye (Lond). 2017 Jan;31(1):10-25. doi: 10.1038/eye.2016.216. Epub 2016 Oct 7. Review.

7.

Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration.

Lipo E, Cashman SM, Kumar-Singh R.

Invest Ophthalmol Vis Sci. 2013 Oct 29;54(10):7107-14. doi: 10.1167/iovs.13-12923.

8.

Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells.

Whitmore SS, Braun TA, Skeie JM, Haas CM, Sohn EH, Stone EM, Scheetz TE, Mullins RF.

Mol Vis. 2013 Nov 16;19:2274-97. eCollection 2013.

9.

Selective accumulation of the complement membrane attack complex in aging choriocapillaris.

Chirco KR, Tucker BA, Stone EM, Mullins RF.

Exp Eye Res. 2016 May;146:393-7. doi: 10.1016/j.exer.2015.09.003. Epub 2015 Sep 11.

10.

Elastin-mediated choroidal endothelial cell migration: possible role in age-related macular degeneration.

Skeie JM, Mullins RF.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5574-80. doi: 10.1167/iovs.08-1984. Epub 2008 Aug 15.

11.

AAV-mediated expression of human PRELP inhibits complement activation, choroidal neovascularization and deposition of membrane attack complex in mice.

Birke MT, Lipo E, Adhi M, Birke K, Kumar-Singh R.

Gene Ther. 2014 May;21(5):507-13. doi: 10.1038/gt.2014.24. Epub 2014 Mar 27.

12.

Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation.

Yan Z, Shi H, Zhu R, Li L, Qin B, Kang L, Chen H, Guan H.

Mol Vis. 2018 Jan 31;24:83-93. eCollection 2018.

13.

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration.

Songstad AE, Wiley LA, Duong K, Kaalberg E, Flamme-Wiese MJ, Cranston CM, Riker MJ, Levasseur D, Stone EM, Mullins RF, Tucker BA.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8258-67. doi: 10.1167/iovs.15-17073.

14.
15.

Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration.

Ma KN, Cashman SM, Sweigard JH, Kumar-Singh R.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6776-83. doi: 10.1167/iovs.10-5887. Epub 2010 Aug 4.

16.

Elevated membrane attack complex in human choroid with high risk complement factor H genotypes.

Mullins RF, Dewald AD, Streb LM, Wang K, Kuehn MH, Stone EM.

Exp Eye Res. 2011 Oct;93(4):565-7. doi: 10.1016/j.exer.2011.06.015. Epub 2011 Jun 26.

17.

Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration.

Wang H, Han X, Kunz E, Hartnett ME.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5525-5534. doi: 10.1167/iovs.16-19691.

18.

A Novel Choroidal Endothelial Cell Line Has a Decreased Affinity for the Age-Related Macular Degeneration-Associated Complement Factor H Variant 402H.

Loeven MA, van Gemst JJ, Schophuizen CMS, Tilakaratna V, van den Heuvel LP, Day AJ, Klevering BJ, van der Vlag J.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):722-730. doi: 10.1167/iovs.IOVS-17-22893.

PMID:
29392318
20.

Aberrant cell and basement membrane architecture contribute to sidestream smoke-induced choroidal endothelial dysfunction.

Yang X, Scott HA, Ardekani S, Williams M, Talbot P, Ghosh K.

Invest Ophthalmol Vis Sci. 2014 Apr 8;55(5):3140-7. doi: 10.1167/iovs.13-13659.

PMID:
24713480

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