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Items: 1 to 20 of 101

1.

Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors.

Chirco KR, Flamme-Wiese MJ, Wiley JS, Potempa LA, Stone EM, Tucker BA, Mullins RF.

Eye (Lond). 2018 Nov;32(11):1740-1742. doi: 10.1038/s41433-018-0170-8. Epub 2018 Jul 16.

PMID:
30013157
2.

Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid.

Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17456-61. Epub 2006 Nov 1.

3.

Elevated membrane attack complex in human choroid with high risk complement factor H genotypes.

Mullins RF, Dewald AD, Streb LM, Wang K, Kuehn MH, Stone EM.

Exp Eye Res. 2011 Oct;93(4):565-7. doi: 10.1016/j.exer.2011.06.015. Epub 2011 Jun 26.

4.

The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.

Mullins RF, Schoo DP, Sohn EH, Flamme-Wiese MJ, Workamelahu G, Johnston RM, Wang K, Tucker BA, Stone EM.

Am J Pathol. 2014 Nov;184(11):3142-53. doi: 10.1016/j.ajpath.2014.07.017. Epub 2014 Sep 7.

5.

C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration.

Bhutto IA, Baba T, Merges C, Juriasinghani V, McLeod DS, Lutty GA.

Br J Ophthalmol. 2011 Sep;95(9):1323-30. doi: 10.1136/bjo.2010.199216. Epub 2011 Jun 1.

6.

CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.

Wang JC, Cao S, Wang A, To E, Law G, Gao J, Zhang D, Cui JZ, Matsubara JA.

Mol Vis. 2015 Mar 13;21:264-72. eCollection 2015.

7.

Assessment of Proteins Associated With Complement Activation and Inflammation in Maculae of Human Donors Homozygous Risk at Chromosome 1 CFH-to-F13B.

Keenan TD, Toso M, Pappas C, Nichols L, Bishop PN, Hageman GS.

Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4870-9. doi: 10.1167/iovs.15-17009.

PMID:
26218915
8.

Monomeric C-reactive protein and inflammation in age-related macular degeneration.

Chirco KR, Whitmore SS, Wang K, Potempa LA, Halder JA, Stone EM, Tucker BA, Mullins RF.

J Pathol. 2016 Oct;240(2):173-83. doi: 10.1002/path.4766. Epub 2016 Sep 19.

9.

Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.

Landowski M, Kelly U, Klingeborn M, Groelle M, Ding JD, Grigsby D, Bowes Rickman C.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3703-3711. doi: 10.1073/pnas.1814014116. Epub 2019 Feb 11.

10.

AAV-mediated expression of human PRELP inhibits complement activation, choroidal neovascularization and deposition of membrane attack complex in mice.

Birke MT, Lipo E, Adhi M, Birke K, Kumar-Singh R.

Gene Ther. 2014 May;21(5):507-13. doi: 10.1038/gt.2014.24. Epub 2014 Mar 27.

11.

Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.

Radu RA, Hu J, Jiang Z, Bok D.

J Biol Chem. 2014 Mar 28;289(13):9113-20. doi: 10.1074/jbc.M114.548669. Epub 2014 Feb 18.

12.

Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration.

Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, de Maat MP, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, van Duijn CM, de Jong PT.

JAMA. 2006 Jul 19;296(3):301-9.

PMID:
16849663
13.

Interaction of complement factor h and fibulin3 in age-related macular degeneration.

Wyatt MK, Tsai JY, Mishra S, Campos M, Jaworski C, Fariss RN, Bernstein SL, Wistow G.

PLoS One. 2013 Jun 28;8(6):e68088. doi: 10.1371/journal.pone.0068088. Print 2013.

14.

Selective accumulation of the complement membrane attack complex in aging choriocapillaris.

Chirco KR, Tucker BA, Stone EM, Mullins RF.

Exp Eye Res. 2016 May;146:393-7. doi: 10.1016/j.exer.2015.09.003. Epub 2015 Sep 11.

15.

C-reactive protein levels and complement factor H polymorphism interaction in age-related macular degeneration and its progression.

Robman L, Baird PN, Dimitrov PN, Richardson AJ, Guymer RH.

Ophthalmology. 2010 Oct;117(10):1982-8. doi: 10.1016/j.ophtha.2010.02.003. Epub 2010 Jun 3.

PMID:
20605213
16.

Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation.

Khandhadia S, Hakobyan S, Heng LZ, Gibson J, Adams DH, Alexander GJ, Gibson JM, Martin KR, Menon G, Nash K, Sivaprasad S, Ennis S, Cree AJ, Morgan BP, Lotery AJ.

Ophthalmology. 2013 Aug;120(8):1612-8. doi: 10.1016/j.ophtha.2013.01.004. Epub 2013 Apr 4.

PMID:
23562165
17.

Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration.

Ferrington DA, Kapphahn RJ, Leary MM, Atilano SR, Terluk MR, Karunadharma P, Chen GK, Ratnapriya R, Swaroop A, Montezuma SR, Kenney MC.

Exp Eye Res. 2016 Apr;145:269-277. doi: 10.1016/j.exer.2016.01.018. Epub 2016 Feb 13.

18.

Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration.

Feng X, Xiao J, Longville B, Tan AX, Wu XN, Cooper MN, McAllister IL, Isaacs T, Palmer LJ, Constable IJ.

Ophthalmology. 2009 Oct;116(10):1908-12.e1. doi: 10.1016/j.ophtha.2009.03.011. Epub 2009 Aug 18.

PMID:
19692124
19.

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

Hughes AE, Bridgett S, Meng W, Li M, Curcio CA, Stambolian D, Bradley DT.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2763-9. doi: 10.1167/iovs.15-18744.

20.

Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.

Clark SJ, Perveen R, Hakobyan S, Morgan BP, Sim RB, Bishop PN, Day AJ.

J Biol Chem. 2010 Sep 24;285(39):30192-202. doi: 10.1074/jbc.M110.103986. Epub 2010 Jul 26.

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