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Items: 1 to 20 of 104

1.

The role of Nrf2 signaling in counteracting neurodegenerative diseases.

Dinkova-Kostova AT, Kostov RV, Kazantsev AG.

FEBS J. 2018 Oct;285(19):3576-3590. doi: 10.1111/febs.14379. Epub 2018 Jan 29. Review.

2.

Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function.

Esteras N, Dinkova-Kostova AT, Abramov AY.

Biol Chem. 2016 May;397(5):383-400. doi: 10.1515/hsz-2015-0295. Review.

PMID:
26812787
3.

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches.

Sivandzade F, Prasad S, Bhalerao A, Cucullo L.

Redox Biol. 2019 Feb;21:101059. doi: 10.1016/j.redox.2018.11.017. Epub 2018 Nov 28. Review.

4.

Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.

Johnson DA, Johnson JA.

Free Radic Biol Med. 2015 Nov;88(Pt B):253-267. doi: 10.1016/j.freeradbiomed.2015.07.147. Epub 2015 Aug 14. Review.

5.

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases.

Joshi G, Johnson JA.

Recent Pat CNS Drug Discov. 2012 Dec;7(3):218-29. Review.

6.

Modulation of mitochondrial dysfunction in neurodegenerative diseases via activation of nuclear factor erythroid-2-related factor 2 by food-derived compounds.

Denzer I, Münch G, Friedland K.

Pharmacol Res. 2016 Jan;103:80-94. doi: 10.1016/j.phrs.2015.11.019. Epub 2015 Nov 25. Review.

PMID:
26626189
7.

The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration.

Johnson JA, Johnson DA, Kraft AD, Calkins MJ, Jakel RJ, Vargas MR, Chen PC.

Ann N Y Acad Sci. 2008 Dec;1147:61-9. doi: 10.1196/annals.1427.036. Review.

8.

Nrf2 Pathway in Age-Related Neurological Disorders: Insights into MicroRNAs.

Paladino S, Conte A, Caggiano R, Pierantoni GM, Faraonio R.

Cell Physiol Biochem. 2018;47(5):1951-1976. doi: 10.1159/000491465. Epub 2018 Jul 3. Review.

9.

[Role of Nrf2 in neurodegenerative diseases and recent progress of its activators].

Zhao CY, Wang XL, Peng Y.

Yao Xue Xue Bao. 2015 Apr;50(4):375-84. Review. Chinese.

PMID:
26223117
10.

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

de Vries HE, Witte M, Hondius D, Rozemuller AJ, Drukarch B, Hoozemans J, van Horssen J.

Free Radic Biol Med. 2008 Nov 15;45(10):1375-83. doi: 10.1016/j.freeradbiomed.2008.09.001. Epub 2008 Sep 13. Review.

PMID:
18824091
11.

Role of the Keap1/Nrf2 pathway in neurodegenerative diseases.

Yamazaki H, Tanji K, Wakabayashi K, Matsuura S, Itoh K.

Pathol Int. 2015 May;65(5):210-9. doi: 10.1111/pin.12261. Epub 2015 Feb 23. Review.

PMID:
25707882
12.

Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases.

Buendia I, Michalska P, Navarro E, Gameiro I, Egea J, León R.

Pharmacol Ther. 2016 Jan;157:84-104. doi: 10.1016/j.pharmthera.2015.11.003. Epub 2015 Nov 23. Review.

PMID:
26617217
13.

Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia.

Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AM, Butterfield DA.

J Neurol Sci. 2005 Jun 15;233(1-2):145-62. Review.

PMID:
15896810
14.

Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters.

Lee DH, Gold R, Linker RA.

Int J Mol Sci. 2012;13(9):11783-803. doi: 10.3390/ijms130911783. Epub 2012 Sep 18.

15.

Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death.

Kumar H, Koppula S, Kim IS, More SV, Kim BW, Choi DK.

CNS Neurol Disord Drug Targets. 2012 Dec;11(8):1015-29. Review.

PMID:
23244425
16.

Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis.

Cheng X, Ku CH, Siow RC.

Free Radic Biol Med. 2013 Sep;64:4-11. doi: 10.1016/j.freeradbiomed.2013.07.025. Epub 2013 Jul 21. Review.

PMID:
23880293
17.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

Kanno T, Tanaka K, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Hirayama N, Ikeda JE.

Free Radic Biol Med. 2012 Dec 1;53(11):2028-42. doi: 10.1016/j.freeradbiomed.2012.09.010. Epub 2012 Sep 20.

PMID:
23000247
18.

Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases.

Lim JL, Wilhelmus MM, de Vries HE, Drukarch B, Hoozemans JJ, van Horssen J.

Arch Toxicol. 2014 Oct;88(10):1773-86. doi: 10.1007/s00204-014-1338-z. Epub 2014 Aug 28. Review.

PMID:
25164826
19.

Nrf2 in health and disease: current and future clinical implications.

Al-Sawaf O, Clarner T, Fragoulis A, Kan YW, Pufe T, Streetz K, Wruck CJ.

Clin Sci (Lond). 2015 Dec;129(12):989-99. doi: 10.1042/CS20150436. Review.

PMID:
26386022
20.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660

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