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Items: 1 to 20 of 99

1.

Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.

Le Guerroué F, Eck F, Jung J, Starzetz T, Mittelbronn M, Kaulich M, Behrends C.

Mol Cell. 2017 Nov 16;68(4):786-796.e6. doi: 10.1016/j.molcel.2017.10.029.

2.

Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites.

Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, Girard-Egrot A, Honnorat J, Moradi-Améli M.

J Biol Chem. 2014 Jan 24;289(4):2261-76. doi: 10.1074/jbc.M113.490862. Epub 2013 Dec 9.

3.

MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.

Nezich CL, Wang C, Fogel AI, Youle RJ.

J Cell Biol. 2015 Aug 3;210(3):435-50. doi: 10.1083/jcb.201501002.

4.

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7.

5.

Bulk autophagy, but not mitophagy, is increased in cellular model of mitochondrial disease.

Morán M, Delmiro A, Blázquez A, Ugalde C, Arenas J, Martín MA.

Biochim Biophys Acta. 2014 Jul;1842(7):1059-70. doi: 10.1016/j.bbadis.2014.03.013. Epub 2014 Apr 2.

6.

Autophagy-related protein 32 acts as autophagic degron and directly initiates mitophagy.

Kondo-Okamoto N, Noda NN, Suzuki SW, Nakatogawa H, Takahashi I, Matsunami M, Hashimoto A, Inagaki F, Ohsumi Y, Okamoto K.

J Biol Chem. 2012 Mar 23;287(13):10631-8. doi: 10.1074/jbc.M111.299917. Epub 2012 Feb 3.

7.

Dissecting the involvement of LC3B and GATE-16 in p62 recruitment into autophagosomes.

Shvets E, Abada A, Weidberg H, Elazar Z.

Autophagy. 2011 Jul;7(7):683-8. Epub 2011 Jul 1.

PMID:
21460636
8.

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.

Metz P, Chiramel A, Chatel-Chaix L, Alvisi G, Bankhead P, Mora-Rodriguez R, Long G, Hamacher-Brady A, Brady NR, Bartenschlager R.

J Virol. 2015 Aug;89(15):8026-41.

9.

Rheb regulates mitophagy induced by mitochondrial energetic status.

Melser S, Chatelain EH, Lavie J, Mahfouf W, Jose C, Obre E, Goorden S, Priault M, Elgersma Y, Rezvani HR, Rossignol R, Bénard G.

Cell Metab. 2013 May 7;17(5):719-30. doi: 10.1016/j.cmet.2013.03.014. Epub 2013 Apr 18.

10.

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M.

J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18.

11.

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.

Ivankovic D, Chau KY, Schapira AH, Gegg ME.

J Neurochem. 2016 Jan;136(2):388-402. doi: 10.1111/jnc.13412. Epub 2015 Nov 24.

12.

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy.

Mancias JD, Wang X, Gygi SP, Harper JW, Kimmelman AC.

Nature. 2014 May 1;509(7498):105-9. doi: 10.1038/nature13148. Epub 2014 Mar 30.

13.

Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation.

Kim I, Lemasters JJ.

Am J Physiol Cell Physiol. 2011 Feb;300(2):C308-17. doi: 10.1152/ajpcell.00056.2010. Epub 2010 Nov 24.

14.

ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase.

Park S, Jang I, Zuber C, Lee Y, Cho JW, Matsuo I, Ito Y, Roth J.

Histochem Cell Biol. 2014 Aug;142(2):153-69. doi: 10.1007/s00418-014-1204-3. Epub 2014 Mar 25.

PMID:
24664425
15.

TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation.

Matsumoto G, Shimogori T, Hattori N, Nukina N.

Hum Mol Genet. 2015 Aug 1;24(15):4429-42. doi: 10.1093/hmg/ddv179. Epub 2015 May 13.

PMID:
25972374
16.

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy.

Liu X, Li Y, Wang X, Xing R, Liu K, Gan Q, Tang C, Gao Z, Jian Y, Luo S, Guo W, Yang C.

J Cell Biol. 2017 May 1;216(5):1301-1320. doi: 10.1083/jcb.201608039. Epub 2017 Apr 12.

17.

The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells.

Padman BS, Bach M, Lucarelli G, Prescott M, Ramm G.

Autophagy. 2013 Nov 1;9(11):1862-75. doi: 10.4161/auto.26557. Epub 2013 Sep 27.

PMID:
24150213
18.

Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes.

Chen Q, Yue F, Li W, Zou J, Xu T, Huang C, Zhang Y, Song K, Huang G, Xu G, Huang H, Li J, Liu L.

J Biol Chem. 2015 Oct 23;290(43):26051-8. doi: 10.1074/jbc.M115.653568. Epub 2015 Sep 11.

19.

Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy.

Park S, Choi SG, Yoo SM, Son JH, Jung YK.

Autophagy. 2014;10(11):1906-20. doi: 10.4161/auto.32177. Epub 2014 Oct 30.

20.

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I.

Mol Cell. 2015 Jan 8;57(1):39-54. doi: 10.1016/j.molcel.2014.11.006. Epub 2014 Dec 11.

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