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Items: 1 to 20 of 105

1.

Comparison of the Toxic Effects of Quinolinic Acid and 3-Nitropropionic Acid in C. elegans: Involvement of the SKN-1 Pathway.

Kotlar I, Colonnello A, Aguilera-González MF, Avila DS, de Lima ME, García-Contreras R, Ortíz-Plata A, Soares FAA, Aschner M, Santamaría A.

Neurotox Res. 2018 Feb;33(2):259-267. doi: 10.1007/s12640-017-9794-x. Epub 2017 Aug 18.

PMID:
28822104
2.

Comparing the Effects of Ferulic Acid and Sugarcane Aqueous Extract in In Vitro and In Vivo Neurotoxic Models.

Colonnello A, Kotlar I, de Lima ME, Ortíz-Plata A, García-Contreras R, Soares FAA, Aschner M, Santamaría A.

Neurotox Res. 2018 Oct;34(3):640-648. doi: 10.1007/s12640-018-9926-y. Epub 2018 Jun 15.

PMID:
29949107
3.

Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition.

Pérez-De La Cruz V, Elinos-Calderón D, Carrillo-Mora P, Silva-Adaya D, Konigsberg M, Morán J, Ali SF, Chánez-Cárdenas ME, Pérez-De La Cruz G, Santamaría A.

Neurochem Int. 2010 May-Jun;56(6-7):834-42. doi: 10.1016/j.neuint.2010.03.008. Epub 2010 Mar 21.

PMID:
20332007
4.

Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro.

Colle D, Hartwig JM, Soares FA, Farina M.

Brain Res Bull. 2012 Mar 10;87(4-5):397-405. doi: 10.1016/j.brainresbull.2012.01.003. Epub 2012 Jan 11.

5.

Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.

Silva-Adaya D, Pérez-De La Cruz V, Herrera-Mundo MN, Mendoza-Macedo K, Villeda-Hernández J, Binienda Z, Ali SF, Santamaría A.

J Neurochem. 2008 May;105(3):677-89. doi: 10.1111/j.1471-4159.2007.05174.x. Epub 2008 Jan 10.

6.

Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway.

Colín-González AL, Luna-López A, Königsberg M, Ali SF, Pedraza-Chaverrí J, Santamaría A.

Neuroscience. 2014 Feb 28;260:130-9. doi: 10.1016/j.neuroscience.2013.12.025. Epub 2013 Dec 19.

PMID:
24361737
7.

Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine.

Elinos-Calderón D, Robledo-Arratia Y, Pérez-De La Cruz V, Maldonado PD, Galván-Arzate S, Pedraza-Chaverrí J, Santamaría A.

J Neural Transm (Vienna). 2010 Jan;117(1):35-44. doi: 10.1007/s00702-009-0299-5. Epub 2009 Oct 29.

PMID:
19866339
8.

Neuroprotective activity of L-theanine on 3-nitropropionic acid-induced neurotoxicity in rat striatum.

Thangarajan S, Deivasigamani A, Natarajan SS, Krishnan P, Mohanan SK.

Int J Neurosci. 2014 Sep;124(9):673-84. doi: 10.3109/00207454.2013.872642. Epub 2014 Jan 23.

PMID:
24325390
9.

Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway.

Dehghan E, Zhang Y, Saremi B, Yadavali S, Hakimi A, Dehghani M, Goodarzi M, Tu X, Robertson S, Lin R, Chudhuri A, Mirzaei H.

Nat Commun. 2017 Dec 20;8(1):2223. doi: 10.1038/s41467-017-02394-3.

10.

Phytochemicals-induced hormesis protects Caenorhabditis elegans against α-synuclein protein aggregation and stress through modulating HSF-1 and SKN-1/Nrf2 signaling pathways.

Govindan S, Amirthalingam M, Duraisamy K, Govindhan T, Sundararaj N, Palanisamy S.

Biomed Pharmacother. 2018 Jun;102:812-822. doi: 10.1016/j.biopha.2018.03.128. Epub 2018 Apr 5.

PMID:
29605769
11.

Early nerve ending rescue from oxidative damage and energy failure by L: -carnitine as post-treatment in two neurotoxic models in rat: recovery of antioxidant and reductive capacities.

Elinos-Calderón D, Robledo-Arratia Y, Pérez-De La Cruz V, Pedraza-Chaverrí J, Ali SF, Santamaría A.

Exp Brain Res. 2009 Aug;197(3):287-96. doi: 10.1007/s00221-009-1913-3. Epub 2009 Jun 30.

PMID:
19565224
12.

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism.

Settivari R, VanDuyn N, LeVora J, Nass R.

Neurotoxicology. 2013 Sep;38:51-60. doi: 10.1016/j.neuro.2013.05.014. Epub 2013 May 27.

13.

Toxic synergism between quinolinic acid and organic acids accumulating in glutaric acidemia type I and in disorders of propionate metabolism in rat brain synaptosomes: Relevance for metabolic acidemias.

Colín-González AL, Paz-Loyola AL, Serratos I, Seminotti B, Ribeiro CA, Leipnitz G, Souza DO, Wajner M, Santamaría A.

Neuroscience. 2015 Nov 12;308:64-74. doi: 10.1016/j.neuroscience.2015.09.002. Epub 2015 Sep 4.

PMID:
26343296
14.

Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells.

Kulasekaran G, Ganapasam S.

Mol Cell Biochem. 2015 Nov;409(1-2):199-211. doi: 10.1007/s11010-015-2525-9. Epub 2015 Aug 18.

PMID:
26280522
15.

Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats.

Khan A, Jamwal S, Bijjem KR, Prakash A, Kumar P.

Neuroscience. 2015 Feb 26;287:66-77. doi: 10.1016/j.neuroscience.2014.12.018. Epub 2014 Dec 20.

PMID:
25536048
16.

The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation.

Powolny AA, Singh SV, Melov S, Hubbard A, Fisher AL.

Exp Gerontol. 2011 Jun;46(6):441-52. doi: 10.1016/j.exger.2011.01.005. Epub 2011 Feb 2.

17.
18.

Rosmarinus officinalis L. increases Caenorhabditis elegans stress resistance and longevity in a DAF-16, HSF-1 and SKN-1-dependent manner.

Zamberlan DC, Amaral GP, Arantes LP, Machado ML, Mizdal CR, Campos MM, Soares FA.

Braz J Med Biol Res. 2016 Aug 1;49(9):e5235. doi: 10.1590/1414-431X20165235.

19.

Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats.

Danduga RCSR, Dondapati SR, Kola PK, Grace L, Tadigiri RVB, Kanakaraju VK.

Biomed Pharmacother. 2018 Sep;105:1254-1268. doi: 10.1016/j.biopha.2018.06.079. Epub 2018 Jun 22.

PMID:
30021362
20.

Quinolinic acid and glutamatergic neurodegeneration in Caenorhabditis elegans.

da Silveira TL, Zamberlan DC, Arantes LP, Machado ML, da Silva TC, Câmara DF, Santamaría A, Aschner M, Soares FAA.

Neurotoxicology. 2018 Jul;67:94-101. doi: 10.1016/j.neuro.2018.04.015. Epub 2018 Apr 24.

PMID:
29702159

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