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Items: 1 to 20 of 102


Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella.

Polajnar M, Dietz MS, Heilemann M, Behrends C.

EMBO Rep. 2017 Sep;18(9):1572-1585. doi: 10.15252/embr.201643851. Epub 2017 Aug 6.


LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB.

Noad J, von der Malsburg A, Pathe C, Michel MA, Komander D, Randow F.

Nat Microbiol. 2017 May 8;2:17063. doi: 10.1038/nmicrobiol.2017.63.


The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium.

Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ.

Cell Host Microbe. 2012 Dec 13;12(6):778-90. doi: 10.1016/j.chom.2012.10.019.


Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation.

van Wijk SJL, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, Grumati P, Kaulich M, Sou YS, Komatsu M, Greten FR, Fulda S, Heilemann M, Dikic I.

Nat Microbiol. 2017 May 8;2:17066. doi: 10.1038/nmicrobiol.2017.66.


Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.

Scott DC, Rhee DY, Duda DM, Kelsall IR, Olszewski JL, Paulo JA, de Jong A, Ovaa H, Alpi AF, Harper JW, Schulman BA.

Cell. 2016 Aug 25;166(5):1198-1214.e24. doi: 10.1016/j.cell.2016.07.027.


LRSAM1, an E3 Ubiquitin ligase with a sense for bacteria.

Celli J.

Cell Host Microbe. 2012 Dec 13;12(6):735-6. doi: 10.1016/j.chom.2012.11.007.


RING-Between-RING E3 Ligases: Emerging Themes amid the Variations.

Dove KK, Klevit RE.

J Mol Biol. 2017 Nov 10;429(22):3363-3375. doi: 10.1016/j.jmb.2017.08.008. Epub 2017 Aug 19. Review.


Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.

Dove KK, Stieglitz B, Duncan ED, Rittinger K, Klevit RE.

EMBO Rep. 2016 Aug;17(8):1221-35. doi: 10.15252/embr.201642641. Epub 2016 Jun 16.


Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

Poirson J, Biquand E, Straub ML, Cassonnet P, Nominé Y, Jones L, van der Werf S, Travé G, Zanier K, Jacob Y, Demeret C, Masson M.

FEBS J. 2017 Oct;284(19):3171-3201. doi: 10.1111/febs.14193. Epub 2017 Aug 29.


Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection.

Fiskin E, Bionda T, Dikic I, Behrends C.

Mol Cell. 2016 Jun 16;62(6):967-981. doi: 10.1016/j.molcel.2016.04.015. Epub 2016 May 19.


Monitoring Ubiquitin-Coated Bacteria via Confocal Microscopy.

Lork M, Delvaeye M, Gonçalves A, Van Hamme E, Beyaert R.

Methods Mol Biol. 2016;1449:243-50. doi: 10.1007/978-1-4939-3756-1_14.


TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR, Duda DM, Olszewski JL, Hofmann K, Knebel A, Langevin F, Wood N, Wightman M, Schulman BA, Alpi AF.

EMBO J. 2013 Oct 30;32(21):2848-60. doi: 10.1038/emboj.2013.209. Epub 2013 Sep 27.


Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.

Yuan L, Lv Z, Atkison JH, Olsen SK.

Nat Commun. 2017 Aug 8;8(1):211. doi: 10.1038/s41467-017-00272-6.


Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.

French ME, Klosowiak JL, Aslanian A, Reed SI, Yates JR 3rd, Hunter T.

J Biol Chem. 2017 Jun 23;292(25):10398-10413. doi: 10.1074/jbc.M117.789479. Epub 2017 May 1.


Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.

Lechtenberg BC, Rajput A, Sanishvili R, Dobaczewska MK, Ware CF, Mace PD, Riedl SJ.

Nature. 2016 Jan 28;529(7587):546-50. doi: 10.1038/nature16511. Epub 2016 Jan 20.


Cytosol as battleground: ubiquitin as a weapon for both host and pathogen.

Collins CA, Brown EJ.

Trends Cell Biol. 2010 Apr;20(4):205-13. doi: 10.1016/j.tcb.2010.01.002. Epub 2010 Feb 1. Review.


UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN.

Park S, Foote PK, Krist DT, Rice SE, Statsyuk AV.

J Biol Chem. 2017 Oct 6;292(40):16539-16553. doi: 10.1074/jbc.M116.773200. Epub 2017 Jul 14.


Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.

Bagola K, von Delbrück M, Dittmar G, Scheffner M, Ziv I, Glickman MH, Ciechanover A, Sommer T.

Mol Cell. 2013 May 23;50(4):528-39. doi: 10.1016/j.molcel.2013.04.005. Epub 2013 May 9.


Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Mediates Ubiquitination-Dependent STAT3 Activation upon Salmonella enterica Serovar Typhimurium Infection.

Ruan HH, Zhang Z, Wang SY, Nickels LM, Tian L, Qiao JJ, Zhu J.

Infect Immun. 2017 Jul 19;85(8). pii: e00081-17. doi: 10.1128/IAI.00081-17. Print 2017 Aug.


Intracellular Salmonella induces aggrephagy of host endomembranes in persistent infections.

López-Montero N, Ramos-Marquès E, Risco C, García-Del Portillo F.

Autophagy. 2016 Oct 2;12(10):1886-1901. Epub 2016 Aug 2.

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