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Items: 1 to 20 of 101

1.

HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.

Veite-Schmahl MJ, Joesten WC, Kennedy MA.

Br J Cancer. 2017 Aug 22;117(5):639-647. doi: 10.1038/bjc.2017.216. Epub 2017 Jul 11.

2.

Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.

He P, Yang JW, Yang VW, Bialkowska AB.

Gastroenterology. 2018 Apr;154(5):1494-1508.e13. doi: 10.1053/j.gastro.2017.12.005. Epub 2017 Dec 15.

PMID:
29248441
3.

Calorie restriction delays the progression of lesions to pancreatic cancer in the LSL-KrasG12D; Pdx-1/Cre mouse model of pancreatic cancer.

Lanza-Jacoby S, Yan G, Radice G, LePhong C, Baliff J, Hess R.

Exp Biol Med (Maywood). 2013 Jul;238(7):787-97. doi: 10.1177/1535370213493727. Epub 2013 Jul 4.

PMID:
23828595
4.

A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.

Philip B, Roland CL, Daniluk J, Liu Y, Chatterjee D, Gomez SB, Ji B, Huang H, Wang H, Fleming JB, Logsdon CD, Cruz-Monserrate Z.

Gastroenterology. 2013 Dec;145(6):1449-58. doi: 10.1053/j.gastro.2013.08.018. Epub 2013 Aug 16.

5.

The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.

Shen R, Wang Q, Cheng S, Liu T, Jiang H, Zhu J, Wu Y, Wang L.

Cancer Lett. 2013 Oct 1;339(1):135-43. doi: 10.1016/j.canlet.2013.07.010. Epub 2013 Jul 22.

6.

Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice.

Bai H, Li H, Zhang W, Matkowskyj KA, Liao J, Srivastava SK, Yang GY.

Carcinogenesis. 2011 Nov;32(11):1689-96. doi: 10.1093/carcin/bgr191. Epub 2011 Aug 22.

7.

Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.

Mohammed A, Qian L, Janakiram NB, Lightfoot S, Steele VE, Rao CV.

Int J Cancer. 2012 Oct 15;131(8):1951-62. doi: 10.1002/ijc.27456. Epub 2012 Mar 14.

8.

GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.

Taki K, Ohmuraya M, Tanji E, Komatsu H, Hashimoto D, Semba K, Araki K, Kawaguchi Y, Baba H, Furukawa T.

Oncogene. 2016 May 5;35(18):2407-12. doi: 10.1038/onc.2015.294. Epub 2015 Aug 10.

PMID:
26257060
9.

Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis.

Ikezawa K, Hikita H, Shigekawa M, Iwahashi K, Eguchi H, Sakamori R, Tatsumi T, Takehara T.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;4(1):185-200.e1. doi: 10.1016/j.jcmgh.2017.02.001. eCollection 2017 Jul.

10.

Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer.

Fendrich V, Schneider R, Maitra A, Jacobsen ID, Opfermann T, Bartsch DK.

Neoplasia. 2011 Feb;13(2):180-6.

11.
12.

Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol.

Husain K, Centeno BA, Chen DT, Fulp WJ, Perez M, Zhang Lee G, Luetteke N, Hingorani SR, Sebti SM, Malafa MP.

Carcinogenesis. 2013 Apr;34(4):858-63. doi: 10.1093/carcin/bgt002. Epub 2013 Jan 9.

13.

Endogenous n-3 polyunsaturated fatty acids delay progression of pancreatic ductal adenocarcinoma in Fat-1-p48(Cre/+)-LSL-Kras(G12D/+) mice.

Mohammed A, Janakiram NB, Brewer M, Duff A, Lightfoot S, Brush RS, Anderson RE, Rao CV.

Neoplasia. 2012 Dec;14(12):1249-59.

14.

Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia.

Shi G, Zhu L, Sun Y, Bettencourt R, Damsz B, Hruban RH, Konieczny SF.

Gastroenterology. 2009 Apr;136(4):1368-78. doi: 10.1053/j.gastro.2008.12.066. Epub 2009 Jan 9.

15.

Simvastatin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer.

Fendrich V, Sparn M, Lauth M, Knoop R, Plassmeier L, Bartsch DK, Waldmann J.

Pancreatology. 2013 Sep-Oct;13(5):502-7. doi: 10.1016/j.pan.2013.08.002. Epub 2013 Aug 20.

PMID:
24075515
16.

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.

Qiu W, Tang SM, Lee S, Turk AT, Sireci AN, Qiu A, Rose C, Xie C, Kitajewski J, Wen HJ, Crawford HC, Sims PA, Hruban RH, Remotti HE, Su GH.

Gastroenterology. 2016 Jan;150(1):218-228.e12. doi: 10.1053/j.gastro.2015.09.013. Epub 2015 Sep 25.

17.

YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.

Gruber R, Panayiotou R, Nye E, Spencer-Dene B, Stamp G, Behrens A.

Gastroenterology. 2016 Sep;151(3):526-39. doi: 10.1053/j.gastro.2016.05.006. Epub 2016 May 20.

18.

The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.

Mohammed A, Janakiram NB, Li Q, Madka V, Ely M, Lightfoot S, Crawford H, Steele VE, Rao CV.

Cancer Prev Res (Phila). 2010 Nov;3(11):1417-26. doi: 10.1158/1940-6207.CAPR-10-0038.

19.

Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.

Rao CV, Mohammed A, Janakiram NB, Li Q, Ritchie RL, Lightfoot S, Vibhudutta A, Steele VE.

Neoplasia. 2012 Sep;14(9):778-87.

20.

NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.

Schmahl MJ, Regan DP, Rivers AC, Joesten WC, Kennedy MA.

PLoS One. 2018 Jul 17;13(7):e0200658. doi: 10.1371/journal.pone.0200658. eCollection 2018.

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