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Items: 1 to 20 of 154

1.

Mammalian ECD Protein Is a Novel Negative Regulator of the PERK Arm of the Unfolded Protein Response.

Olou AA, Sarkar A, Bele A, Gurumurthy CB, Mir RA, Ammons SA, Mirza S, Saleem I, Urano F, Band H, Band V.

Mol Cell Biol. 2017 Aug 28;37(18). pii: e00030-17. doi: 10.1128/MCB.00030-17. Print 2017 Sep 15.

2.

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2011 Nov;22(22):4390-405. doi: 10.1091/mbc.E11-06-0510. Epub 2011 Sep 14.

3.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K.

J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6.

4.

The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.

Ogborn DI, McKay BR, Crane JD, Parise G, Tarnopolsky MA.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R664-9. doi: 10.1152/ajpregu.00511.2013. Epub 2014 Jul 9.

5.

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.

Hulmi JJ, Hentilä J, DeRuisseau KC, Oliveira BM, Papaioannou KG, Autio R, Kujala UM, Ritvos O, Kainulainen H, Korkmaz A, Atalay M.

Free Radic Biol Med. 2016 Oct;99:308-322. doi: 10.1016/j.freeradbiomed.2016.08.017. Epub 2016 Aug 20.

PMID:
27554968
6.

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

Baird TD, Palam LR, Fusakio ME, Willy JA, Davis CM, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2014 May;25(10):1686-97. doi: 10.1091/mbc.E14-02-0704. Epub 2014 Mar 19.

7.

TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.

Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.

PLoS One. 2014 Nov 13;9(11):e112761. doi: 10.1371/journal.pone.0112761. eCollection 2014.

8.

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response.

Hiramatsu N, Messah C, Han J, LaVail MM, Kaufman RJ, Lin JH.

Mol Biol Cell. 2014 May;25(9):1411-20. doi: 10.1091/mbc.E13-11-0664. Epub 2014 Mar 12.

9.

Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M.

J Biol Chem. 2014 May 2;289(18):12593-611. doi: 10.1074/jbc.M113.543215. Epub 2014 Mar 19.

10.

The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.

Xue M, Fu F, Ma Y, Zhang X, Li L, Feng L, Liu P.

J Virol. 2018 Jul 17;92(15). pii: e00431-18. doi: 10.1128/JVI.00431-18. Print 2018 Aug 1.

PMID:
29769338
11.

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.

Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochem Pharmacol. 2016 Jun 1;109:27-47. doi: 10.1016/j.bcp.2016.04.001. Epub 2016 Apr 6.

PMID:
27059255
12.

Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production.

Flores-Martín J, Reyna L, Ridano ME, Panzetta-Dutari GM, Genti-Raimondi S.

Free Radic Biol Med. 2016 Oct;99:286-295. doi: 10.1016/j.freeradbiomed.2016.08.023. Epub 2016 Aug 20.

PMID:
27554972
13.

Different Roles of GRP78 on Cell Proliferation and Apoptosis in Cartilage Development.

Xiong Z, Jiang R, Li X, Liu Y, Guo F.

Int J Mol Sci. 2015 Sep 7;16(9):21153-76. doi: 10.3390/ijms160921153.

14.

Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.

15.

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR).

Kranz P, Neumann F, Wolf A, Classen F, Pompsch M, Ocklenburg T, Baumann J, Janke K, Baumann M, Goepelt K, Riffkin H, Metzen E, Brockmeier U.

Cell Death Dis. 2017 Aug 10;8(8):e2986. doi: 10.1038/cddis.2017.369.

16.
17.

Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.

Tsutsumi S, Namba T, Tanaka KI, Arai Y, Ishihara T, Aburaya M, Mima S, Hoshino T, Mizushima T.

Oncogene. 2006 Feb 16;25(7):1018-29.

PMID:
16205636
18.

Methods for analyzing eIF2 kinases and translational control in the unfolded protein response.

Teske BF, Baird TD, Wek RC.

Methods Enzymol. 2011;490:333-56. doi: 10.1016/B978-0-12-385114-7.00019-2.

PMID:
21266259
19.

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.

Roobol A, Roobol J, Bastide A, Knight JR, Willis AE, Smales CM.

Biochem J. 2015 Jan 15;465(2):213-25. doi: 10.1042/BJ20140852.

PMID:
25329545
20.

Pancreatic β-cells depend on basal expression of active ATF6α-p50 for cell survival even under nonstress conditions.

Teodoro T, Odisho T, Sidorova E, Volchuk A.

Am J Physiol Cell Physiol. 2012 Apr 1;302(7):C992-1003. doi: 10.1152/ajpcell.00160.2011. Epub 2011 Dec 21.

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