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Items: 1 to 20 of 100

1.

Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation.

Johansson BB, Fjeld K, Solheim MH, Shirakawa J, Zhang E, Keindl M, Hu J, Lindqvist A, Døskeland A, Mellgren G, Flatmark T, Njølstad PR, Kulkarni RN, Wierup N, Aukrust I, Bjørkhaug L.

Mol Cell Endocrinol. 2017 Oct 15;454:146-157. doi: 10.1016/j.mce.2017.06.020. Epub 2017 Jun 22.

PMID:
28648619
2.

Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner.

Hofmeister-Brix A, Kollmann K, Langer S, Schultz J, Lenzen S, Baltrusch S.

J Biol Chem. 2013 Dec 13;288(50):35824-39. doi: 10.1074/jbc.M113.526632. Epub 2013 Nov 1.

3.

SUMOylation of pancreatic glucokinase regulates its cellular stability and activity.

Aukrust I, Bjørkhaug L, Negahdar M, Molnes J, Johansson BB, Müller Y, Haas W, Gygi SP, Søvik O, Flatmark T, Kulkarni RN, Njølstad PR.

J Biol Chem. 2013 Feb 22;288(8):5951-62. doi: 10.1074/jbc.M112.393769. Epub 2013 Jan 7.

4.

Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).

Meur G, Qian Q, da Silva Xavier G, Pullen TJ, Tsuboi T, McKinnon C, Fletcher L, Tavaré JM, Hughes S, Johnson P, Rutter GA.

J Biol Chem. 2011 Apr 15;286(15):13647-56. doi: 10.1074/jbc.M110.204248. Epub 2011 Feb 18.

5.

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.

6.

Characterization of two MODY2 mutations with different susceptibility to activation.

Langer S, Platz C, Waterstradt R, Baltrusch S.

Biochem Biophys Res Commun. 2015 Sep 4;464(4):1113-1119. doi: 10.1016/j.bbrc.2015.07.088. Epub 2015 Jul 21.

PMID:
26208450
7.

Glucokinase and glucokinase regulatory protein: mutual dependence for nuclear localization.

Bosco D, Meda P, Iynedjian PB.

Biochem J. 2000 May 15;348 Pt 1:215-22.

8.

Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation.

Chung J, Khadka P, Chung IK.

J Cell Sci. 2012 Jun 1;125(Pt 11):2684-97. doi: 10.1242/jcs.099267. Epub 2012 Feb 24.

9.

Sumoylation of SAE2 C terminus regulates SAE nuclear localization.

Truong K, Lee TD, Li B, Chen Y.

J Biol Chem. 2012 Dec 14;287(51):42611-9. doi: 10.1074/jbc.M112.420877. Epub 2012 Oct 24.

10.

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y.

Diabetologia. 1993 Nov;36(11):1139-45.

PMID:
8270128
11.

A novel conserved nuclear localization signal is recognized by a group of yeast importins.

Fries T, Betz C, Sohn K, Caesar S, Schlenstedt G, Bailer SM.

J Biol Chem. 2007 Jul 6;282(27):19292-301. Epub 2007 May 7.

12.

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

Biochem J. 2008 Apr 1;411(1):41-51.

PMID:
18039179
13.

Glucose mediates the translocation of NeuroD1 by O-linked glycosylation.

Andrali SS, Qian Q, Ozcan S.

J Biol Chem. 2007 May 25;282(21):15589-96. Epub 2007 Apr 2.

14.

Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β-cells.

Sato H, Nagashima K, Ogura M, Sato Y, Tahara Y, Ogura K, Yamano G, Sugizaki K, Fujita N, Tatsuoka H, Usui R, Mukai E, Fujimoto S, Inagaki N.

J Diabetes Investig. 2016 Mar;7(2):171-8. doi: 10.1111/jdi.12407. Epub 2015 Sep 13.

15.

Glucose-induced dissociation of glucokinase from its regulatory protein in the nucleus of hepatocytes prior to nuclear export.

Kaminski MT, Schultz J, Waterstradt R, Tiedge M, Lenzen S, Baltrusch S.

Biochim Biophys Acta. 2014 Mar;1843(3):554-64.

16.

Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation.

Kumari G, Singhal PK, Suryaraja R, Mahalingam S.

J Mol Biol. 2010 Mar 19;397(1):89-109. doi: 10.1016/j.jmb.2010.01.005. Epub 2010 Jan 11.

PMID:
20064523
17.

Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6).

Guillemain G, Da Silva Xavier G, Rafiq I, Leturque A, Rutter GA.

Biochem J. 2004 Feb 15;378(Pt 1):219-27.

18.
19.

Nuclear import of human sexual regulator DMRT1 is mediated by importin-beta.

Ying M, Chen B, Tian Y, Hou Y, Li Q, Shang X, Sun J, Cheng H, Zhou R.

Biochim Biophys Acta. 2007 Jun;1773(6):804-13. Epub 2007 Mar 24. Erratum in: Biochim Biophys Acta. 2008 Aug;1783(8):1561.

20.

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