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Items: 1 to 20 of 106

1.

Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells.

Yang S, Jan YH, Mishin V, Heck DE, Laskin DL, Laskin JD.

Chem Res Toxicol. 2017 Jul 17;30(7):1406-1418. doi: 10.1021/acs.chemrestox.7b00052. Epub 2017 Jun 26.

2.

Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells.

Yang S, Jan YH, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.

J Biol Chem. 2013 Jun 28;288(26):19221-37. doi: 10.1074/jbc.M112.402164. Epub 2013 May 2.

3.

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

Szilagyi JT, Fussell KC, Wang Y, Jan YH, Mishin V, Richardson JR, Heck DE, Yang S, Aleksunes LM, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2018 Sep 14. pii: S0041-008X(18)30417-4. doi: 10.1016/j.taap.2018.09.011. [Epub ahead of print]

PMID:
30222979
4.

Dicarbonyl/l-xylulose reductase (DCXR): The multifunctional pentosuria enzyme.

Lee SK, Son le T, Choi HJ, Ahnn J.

Int J Biochem Cell Biol. 2013 Nov;45(11):2563-7. doi: 10.1016/j.biocel.2013.08.010. Epub 2013 Aug 27. Review.

PMID:
23988570
5.

Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.

Nakagawa J, Ishikura S, Asami J, Isaji T, Usami N, Hara A, Sakurai T, Tsuritani K, Oda K, Takahashi M, Yoshimoto M, Otsuka N, Kitamura K.

J Biol Chem. 2002 May 17;277(20):17883-91. Epub 2002 Mar 6.

6.

Human DCXR - another 'moonlighting protein' involved in sugar metabolism, carbonyl detoxification, cell adhesion and male fertility?

Ebert B, Kisiela M, Maser E.

Biol Rev Camb Philos Soc. 2015 Feb;90(1):254-78. doi: 10.1111/brv.12108. Epub 2014 Apr 10. Review.

PMID:
24720935
7.

(-)-Epigallocatechin-3-gallate, a potential inhibitor to human dicarbonyl/L-xylulose reductase.

Hu XH, Ding LY, Huang WX, Yang XM, Xie F, Xu M, Yu L.

J Biochem. 2013 Aug;154(2):167-75. doi: 10.1093/jb/mvt039. Epub 2013 May 9.

PMID:
23661708
8.

Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.

Hubbs AF, Fluharty KL, Edwards RJ, Barnabei JL, Grantham JT, Palmer SM, Kelly F, Sargent LM, Reynolds SH, Mercer RR, Goravanahally MP, Kashon ML, Honaker JC, Jackson MC, Cumpston AM, Goldsmith WT, McKinney W, Fedan JS, Battelli LA, Munro T, Bucklew-Moyers W, McKinstry K, Schwegler-Berry D, Friend S, Knepp AK, Smith SL, Sriram K.

Am J Pathol. 2016 Nov;186(11):2887-2908. doi: 10.1016/j.ajpath.2016.07.018.

9.

Dicarbonyl L-xylulose reductase (DCXR), a "moonlighting protein" in the bovine epididymis.

Akintayo A, Légaré C, Sullivan R.

PLoS One. 2015 Mar 27;10(3):e0120869. doi: 10.1371/journal.pone.0120869. eCollection 2015.

10.

Molecular cloning, expression and tissue distribution of hamster diacetyl reductase. Identity with L-xylulose reductase.

Ishikura S, Isaji T, Usami N, Kitahara K, Nakagawa J, Hara A.

Chem Biol Interact. 2001 Jan 30;130-132(1-3):879-89.

PMID:
11306103
11.

Garrod's fourth inborn error of metabolism solved by the identification of mutations causing pentosuria.

Pierce SB, Spurrell CH, Mandell JB, Lee MK, Zeligson S, Bereman MS, Stray SM, Fokstuen S, MacCoss MJ, Levy-Lahad E, King MC, Motulsky AG.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18313-7. doi: 10.1073/pnas.1115888108. Epub 2011 Oct 31.

12.

Transgenic mice over-expressing dicarbonyl/L-xylulose reductase gene crossed with KK-Ay diabetic model mice: an animal model for the metabolism of renal carbonyl compounds.

Sudo T, Ishii A, Asami J, Uematsu Y, Saitoh M, Nakamura A, Tada N, Ohnuki T, Komurasaki T, Nakagawa J.

Exp Anim. 2005 Oct;54(5):385-94.

13.

DHS-21, a dicarbonyl/L-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans.

Son le T, Ko KM, Cho JH, Singaravelu G, Chatterjee I, Choi TW, Song HO, Yu JR, Park BJ, Lee SK, Ahnn J.

FEBS Lett. 2011 May 6;585(9):1310-6. doi: 10.1016/j.febslet.2011.03.062. Epub 2011 Apr 6.

14.

Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.

Shultz CA, Quinn AM, Park JH, Harvey RG, Bolton JL, Maser E, Penning TM.

Chem Res Toxicol. 2011 Dec 19;24(12):2153-66. doi: 10.1021/tx200294c. Epub 2011 Sep 29.

15.

Suppression of renal alpha-dicarbonyl compounds generated following ureteral obstruction by kidney-specific alpha-dicarbonyl/L-xylulose reductase.

Odani H, Asami J, Ishii A, Oide K, Sudo T, Nakamura A, Miyata N, Otsuka N, Maeda K, Nakagawa J.

Ann N Y Acad Sci. 2008 Apr;1126:320-4. Epub 2007 Dec 13.

PMID:
18079483
16.

Dicarbonyl/L-xylulose reductase: a potential biomarker identified by laser-capture microdissection-micro serial analysis of gene expression of human prostate adenocarcinoma.

Cho-Vega JH, Tsavachidis S, Do KA, Nakagawa J, Medeiros LJ, McDonnell TJ.

Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2615-22.

17.

Bioinformatic and biochemical characterization of DCXR and DHRS2/4 from Caenorhabditis elegans.

Kisiela M, El-Hawari Y, Martin HJ, Maser E.

Chem Biol Interact. 2011 May 30;191(1-3):75-82. doi: 10.1016/j.cbi.2011.01.034. Epub 2011 Feb 15.

PMID:
21300042
19.

Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs.

Hara A, Endo S, Matsunaga T, El-Kabbani O, Miura T, Nishinaka T, Terada T.

Biochem Pharmacol. 2017 Aug 15;138:185-192. doi: 10.1016/j.bcp.2017.04.023. Epub 2017 Apr 24.

PMID:
28450226
20.

Alpha,beta-dicarbonyl reduction by Saccharomyces D-arabinose dehydrogenase.

van Bergen B, Strasser R, Cyr N, Sheppard JD, Jardim A.

Biochim Biophys Acta. 2006 Nov;1760(11):1636-45. Epub 2006 Sep 8.

PMID:
17030441

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