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Items: 1 to 20 of 99

1.

Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms.

Solinski AE, Koval AB, Brzozowski RS, Morrison KR, Fraboni AJ, Carson CE, Eshraghi AR, Zhou G, Quivey RG Jr, Voelz VA, Buttaro BA, Wuest WM.

J Am Chem Soc. 2017 May 31;139(21):7188-7191. doi: 10.1021/jacs.7b03879. Epub 2017 May 17.

2.

The carolactam strategy is ineffective: synthesis and biological evaluation of carolactam.

Ammermann J, Schmidt T, Donner J, Reck M, Dalton M, Stumpp N, Stiesch M, Wagner-Döbler I, Kirschning A.

Org Biomol Chem. 2017 Oct 18;15(40):8553-8558. doi: 10.1039/c7ob02060k.

PMID:
28972613
3.

Synthesis of new carolacton derivatives and their activity against biofilms of oral bacteria.

Stumpp N, Premnath P, Schmidt T, Ammermann J, Dräger G, Reck M, Jansen R, Stiesch M, Wagner-Döbler I, Kirschning A.

Org Biomol Chem. 2015 May 28;13(20):5765-74. doi: 10.1039/c5ob00460h. Epub 2015 Apr 22.

PMID:
25902328
4.

Two-dimensional gel-based proteomic of the caries causative bacterium Streptococcus mutans UA159 and insight into the inhibitory effect of carolacton.

Li J, Wang W, Wang Y, Zeng AP.

Proteomics. 2013 Dec;13(23-24):3470-7. doi: 10.1002/pmic.201300077. Epub 2013 Nov 20.

PMID:
24170661
5.

Damage of Streptococcus mutans biofilms by carolacton, a secondary metabolite from the myxobacterium Sorangium cellulosum.

Kunze B, Reck M, Dötsch A, Lemme A, Schummer D, Irschik H, Steinmetz H, Wagner-Döbler I.

BMC Microbiol. 2010 Jul 26;10:199. doi: 10.1186/1471-2180-10-199.

6.

A concise synthesis of carolacton.

Hallside MS, Brzozowski RS, Wuest WM, Phillips AJ.

Org Lett. 2014 Feb 21;16(4):1148-51. doi: 10.1021/ol500004k. Epub 2014 Jan 31.

7.

Dental composite materials containing carolacton inhibit biofilm growth of Streptococcus mutans.

Apel C, Barg A, Rheinberg A, Conrads G, Wagner-Döbler I.

Dent Mater. 2013 Nov;29(11):1188-99. doi: 10.1016/j.dental.2013.09.005. Epub 2013 Oct 4.

PMID:
24094824
8.

Total synthesis of carolacton, a highly potent biofilm inhibitor.

Schmidt T, Kirschning A.

Angew Chem Int Ed Engl. 2012 Jan 23;51(4):1063-6. doi: 10.1002/anie.201106762. Epub 2011 Dec 9. No abstract available.

PMID:
22162345
9.

The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target.

Donner J, Reck M, Bergmann S, Kirschning A, Müller R, Wagner-Döbler I.

Sci Rep. 2016 Jul 11;6:29677. doi: 10.1038/srep29677.

10.

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.

Nijampatnam B, Casals L, Zheng R, Wu H, Velu SE.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3508-13. doi: 10.1016/j.bmcl.2016.06.033. Epub 2016 Jun 14.

11.

Construction and verification of the transcriptional regulatory response network of Streptococcus mutans upon treatment with the biofilm inhibitor carolacton.

Sudhakar P, Reck M, Wang W, He FQ, Wagner-Döbler I, Zeng AP.

BMC Genomics. 2014 May 12;15:362. doi: 10.1186/1471-2164-15-362. Erratum in: BMC Genomics. 2014;15:739. Dobler, Irene W [corrected to Wagner-Döbler, Irene].

12.

[Carolacton--a highly potent inhibitor of biofilms].

Schmitz J.

Pharm Unserer Zeit. 2012 Jul;41(4):271. doi: 10.1002/pauz.201290067. German. No abstract available.

PMID:
22763994
13.

The biofilm inhibitor carolacton disturbs membrane integrity and cell division of Streptococcus mutans through the serine/threonine protein kinase PknB.

Reck M, Rutz K, Kunze B, Tomasch J, Surapaneni SK, Schulz S, Wagner-Döbler I.

J Bacteriol. 2011 Oct;193(20):5692-706. doi: 10.1128/JB.05424-11. Epub 2011 Aug 12.

14.

Antimicrobial and anti-biofilm effect of Bac8c on major bacteria associated with dental caries and Streptococcus mutans biofilms.

Ding Y, Wang W, Fan M, Tong Z, Kuang R, Jiang W, Ni L.

Peptides. 2014 Feb;52:61-7. doi: 10.1016/j.peptides.2013.11.020. Epub 2013 Dec 3.

PMID:
24309076
15.

Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms.

Mogen AB, Chen F, Ahn SJ, Burne RA, Wang D, Rice KC.

PLoS One. 2015 Jul 29;10(7):e0133886. doi: 10.1371/journal.pone.0133886. eCollection 2015.

16.

Inhibition of Streptococcus mutans biofilm formation, extracellular polysaccharide production, and virulence by an oxazole derivative.

Chen L, Ren Z, Zhou X, Zeng J, Zou J, Li Y.

Appl Microbiol Biotechnol. 2016 Jan;100(2):857-67. doi: 10.1007/s00253-015-7092-1. Epub 2015 Nov 3.

PMID:
26526453
17.

The synthetic human beta-defensin-3 C15 peptide exhibits antimicrobial activity against Streptococcus mutans, both alone and in combination with dental disinfectants.

Ahn KB, Kim AR, Kum KY, Yun CH, Han SH.

J Microbiol. 2017 Oct;55(10):830-836. doi: 10.1007/s12275-017-7362-y. Epub 2017 Sep 28.

PMID:
28956355
18.

Antibiofilm Activity of Chilean Propolis on Streptococcus mutans Is Influenced by the Year of Collection.

Veloz JJ, Saavedra N, Lillo A, Alvear M, Barrientos L, Salazar LA.

Biomed Res Int. 2015;2015:291351. doi: 10.1155/2015/291351. Epub 2015 Jul 12.

19.

In vitro activity of xanthorrhizol against Streptococcus mutans biofilms.

Rukayadi Y, Hwang JK.

Lett Appl Microbiol. 2006 Apr;42(4):400-4.

20.

Effect of the Biofilm Age and Starvation on Acid Tolerance of Biofilm Formed by Streptococcus mutans Isolated from Caries-Active and Caries-Free Adults.

Jiang S, Chen S, Zhang C, Zhao X, Huang X, Cai Z.

Int J Mol Sci. 2017 Mar 30;18(4). pii: E713. doi: 10.3390/ijms18040713.

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