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Items: 1 to 20 of 79

1.

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.

Sinitskiy AV, Stanley NH, Hackos DH, Hanson JE, Sellers BD, Pande VS.

Sci Rep. 2017 Apr 5;7:44578. doi: 10.1038/srep44578.

2.

Simulated Dynamics of Glycans on Ligand-Binding Domain of NMDA Receptors Reveals Strong Dynamic Coupling between Glycans and Protein Core.

Sinitskiy AV, Pande VS.

J Chem Theory Comput. 2017 Nov 14;13(11):5496-5505. doi: 10.1021/acs.jctc.7b00817. Epub 2017 Oct 31.

PMID:
29019687
3.

Biochemical and electrophysiological characterization of N-glycans on NMDA receptor subunits.

Kaniakova M, Lichnerova K, Skrenkova K, Vyklicky L, Horak M.

J Neurochem. 2016 Aug;138(4):546-56. doi: 10.1111/jnc.13679. Epub 2016 Jun 15.

4.

Molecular dynamics study-based mechanism of nefiracetam-induced NMDA receptor potentiation.

Omotuyi OI, Ueda H.

Comput Biol Chem. 2015 Apr;55:14-22. doi: 10.1016/j.compbiolchem.2015.01.004. Epub 2015 Jan 23.

PMID:
25659913
5.

A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors.

Chopra DA, Sapkota K, Irvine MW, Fang G, Jane DE, Monaghan DT, Dravid SM.

Sci Rep. 2017 Jul 31;7(1):6933. doi: 10.1038/s41598-017-07292-8.

6.

Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain.

Zhu S, Stroebel D, Yao CA, Taly A, Paoletti P.

Nat Struct Mol Biol. 2013 Apr;20(4):477-85. doi: 10.1038/nsmb.2522. Epub 2013 Mar 3.

PMID:
23454977
7.

Structural mechanism of N-methyl-D-aspartate receptor type 1 partial agonism.

Ylilauri M, Pentikäinen OT.

PLoS One. 2012;7(10):e47604. doi: 10.1371/journal.pone.0047604. Epub 2012 Oct 15.

8.

Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity.

Bledsoe D, Tamer C, Mesic I, Madry C, Klein BG, Laube B, Costa BM.

Front Pharmacol. 2017 May 9;8:229. doi: 10.3389/fphar.2017.00229. eCollection 2017.

9.

Ethanol inhibition of constitutively open N-methyl-D-aspartate receptors.

Xu M, Smothers CT, Trudell J, Woodward JJ.

J Pharmacol Exp Ther. 2012 Jan;340(1):218-26. doi: 10.1124/jpet.111.187179. Epub 2011 Oct 17.

10.

Conformational analysis of NMDA receptor GluN1, GluN2, and GluN3 ligand-binding domains reveals subtype-specific characteristics.

Yao Y, Belcher J, Berger AJ, Mayer ML, Lau AY.

Structure. 2013 Oct 8;21(10):1788-99. doi: 10.1016/j.str.2013.07.011. Epub 2013 Aug 22.

11.

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.

Karakas E, Simorowski N, Furukawa H.

Nature. 2011 Jun 15;475(7355):249-53. doi: 10.1038/nature10180.

12.

Two N-glycosylation Sites in the GluN1 Subunit Are Essential for Releasing N-methyl-d-aspartate (NMDA) Receptors from the Endoplasmic Reticulum.

Lichnerova K, Kaniakova M, Park SP, Skrenkova K, Wang YX, Petralia RS, Suh YH, Horak M.

J Biol Chem. 2015 Jul 24;290(30):18379-90. doi: 10.1074/jbc.M115.656546. Epub 2015 Jun 4.

13.

A novel family of negative and positive allosteric modulators of NMDA receptors.

Costa BM, Irvine MW, Fang G, Eaves RJ, Mayo-Martin MB, Skifter DA, Jane DE, Monaghan DT.

J Pharmacol Exp Ther. 2010 Dec;335(3):614-21. doi: 10.1124/jpet.110.174144. Epub 2010 Sep 21.

14.

Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors.

Kvist T, Greenwood JR, Hansen KB, Traynelis SF, Bräuner-Osborne H.

Neuropharmacology. 2013 Dec;75:324-36. doi: 10.1016/j.neuropharm.2013.08.003. Epub 2013 Aug 22.

15.

Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.

Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF.

Mol Pharmacol. 2014 Nov;86(5):548-60. doi: 10.1124/mol.114.094516. Epub 2014 Sep 9.

16.

Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines.

Mony L, Zhu S, Carvalho S, Paoletti P.

EMBO J. 2011 Jun 17;30(15):3134-46. doi: 10.1038/emboj.2011.203.

17.

N-Glycosylation Regulates the Trafficking and Surface Mobility of GluN3A-Containing NMDA Receptors.

Skrenkova K, Lee S, Lichnerova K, Kaniakova M, Hansikova H, Zapotocky M, Suh YH, Horak M.

Front Mol Neurosci. 2018 Jun 4;11:188. doi: 10.3389/fnmol.2018.00188. eCollection 2018.

18.

Pharmacology of triheteromeric N-Methyl-D-Aspartate Receptors.

Cheriyan J, Balsara RD, Hansen KB, Castellino FJ.

Neurosci Lett. 2016 Mar 23;617:240-6. doi: 10.1016/j.neulet.2016.02.032. Epub 2016 Feb 23.

19.

Inhibition of rat recombinant GluN1/GluN2A and GluN1/GluN2B NMDA receptors by ethanol at concentrations based on the US/UK drink-drive limit.

Otton HJ, Janssen A, O'Leary T, Chen PE, Wyllie DJ.

Eur J Pharmacol. 2009 Jul 1;614(1-3):14-21. doi: 10.1016/j.ejphar.2009.04.034. Epub 2009 Apr 24.

PMID:
19394328
20.

Conformational transitions in the glycine-bound GluN1 NMDA receptor LBD via single-molecule FRET.

Cooper DR, Dolino DM, Jaurich H, Shuang B, Ramaswamy S, Nurik CE, Chen J, Jayaraman V, Landes CF.

Biophys J. 2015 Jul 7;109(1):66-75. doi: 10.1016/j.bpj.2015.05.025.

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