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The future is now: neuroprotection during cardiopulmonary resuscitation.

Moore JC, Bartos JA, Matsuura TR, Yannopoulos D.

Curr Opin Crit Care. 2017 Jun;23(3):215-222. doi: 10.1097/MCC.0000000000000405. Review.


Head and thorax elevation during active compression decompression cardiopulmonary resuscitation with an impedance threshold device improves cerebral perfusion in a swine model of prolonged cardiac arrest.

Moore JC, Segal N, Lick MC, Dodd KW, Salverda BJ, Hinke MB, Robinson AE, Debaty G, Lurie KG.

Resuscitation. 2017 Dec;121:195-200. doi: 10.1016/j.resuscitation.2017.07.033. Epub 2017 Aug 5.


Miniaturized mechanical chest compressor improves calculated cerebral perfusion pressure without compromising intracranial pressure during cardiopulmonary resuscitation in a porcine model of cardiac arrest.

Xu J, Hu X, Yang Z, Wu X, Bisera J, Sun S, Tang W.

Resuscitation. 2014 May;85(5):683-8. doi: 10.1016/j.resuscitation.2014.01.014. Epub 2014 Jan 23.


Effects of incomplete chest wall decompression during cardiopulmonary resuscitation on coronary and cerebral perfusion pressures in a porcine model of cardiac arrest.

Yannopoulos D, McKnite S, Aufderheide TP, Sigurdsson G, Pirrallo RG, Benditt D, Lurie KG.

Resuscitation. 2005 Mar;64(3):363-72.


Sodium nitroprusside enhanced cardiopulmonary resuscitation improves survival with good neurological function in a porcine model of prolonged cardiac arrest.

Yannopoulos D, Matsuura T, Schultz J, Rudser K, Halperin HR, Lurie KG.

Crit Care Med. 2011 Jun;39(6):1269-74. doi: 10.1097/CCM.0b013e31820ed8a6.


Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest.

Bartos JA, Matsuura TR, Sarraf M, Youngquist ST, McKnite SH, Rees JN, Sloper DT, Bates FS, Segal N, Debaty G, Lurie KG, Neumar RW, Metzger JM, Riess ML, Yannopoulos D.

Resuscitation. 2015 Feb;87:7-13. doi: 10.1016/j.resuscitation.2014.10.019. Epub 2014 Nov 20.


Enhanced perfusion during advanced life support improves survival with favorable neurologic function in a porcine model of refractory cardiac arrest.

Debaty G, Metzger A, Rees J, McKnite S, Puertas L, Yannopoulos D, Lurie K.

Crit Care Med. 2015 May;43(5):1087-95. doi: 10.1097/CCM.0000000000000939.


The Effect of Head Up Cardiopulmonary Resuscitation on Cerebral and Systemic Hemodynamics.

Ryu HH, Moore JC, Yannopoulos D, Lick M, McKnite S, Shin SD, Kim TY, Metzger A, Rees J, Tsangaris A, Debaty G, Lurie KG.

Resuscitation. 2016 May;102:29-34. doi: 10.1016/j.resuscitation.2016.01.033. Epub 2016 Feb 22.


A tourniquet assisted cardiopulmonary resuscitation augments myocardial perfusion in a porcine model of cardiac arrest.

Yang Z, Tang D, Wu X, Hu X, Xu J, Qian J, Yang M, Tang W.

Resuscitation. 2015 Jan;86:49-53. doi: 10.1016/j.resuscitation.2014.10.009. Epub 2014 Oct 23.


Effects of active compression-decompression resuscitation on myocardial and cerebral blood flow in pigs.

Lindner KH, Pfenninger EG, Lurie KG, Schürmann W, Lindner IM, Ahnefeld FW.

Circulation. 1993 Sep;88(3):1254-63.


Sodium nitroprusside-enhanced cardiopulmonary resuscitation improves resuscitation rates after prolonged untreated cardiac arrest in two porcine models.

Schultz JC, Segal N, Caldwell E, Kolbeck J, McKnite S, Lebedoff N, Zviman M, Aufderheide TP, Yannopoulos D.

Crit Care Med. 2011 Dec;39(12):2705-10. doi: 10.1097/CCM.0b013e31822668ba.


[Effects of interrupted abdominal aorta compression on cardiopulmonary cerebral resuscitation after cardiac arrest in rabbit].

Dou W, Wang L, Liu H, Zhang P, Guo C, Liu Y, Ma L, Sun K, Ma W, Wang Q, Guo X.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014 Oct;26(10):718-21. doi: 10.3760/cma.j.issn.2095-4352.2014.10.008. Chinese.


Reperfusion injury protection during Basic Life Support improves circulation and survival outcomes in a porcine model of prolonged cardiac arrest.

Debaty G, Lurie K, Metzger A, Lick M, Bartos JA, Rees JN, McKnite S, Puertas L, Pepe P, Fowler R, Yannopoulos D.

Resuscitation. 2016 Aug;105:29-35. doi: 10.1016/j.resuscitation.2016.05.008. Epub 2016 May 20.


Intrathoracic pressure regulator during continuous-chest-compression advanced cardiac resuscitation improves vital organ perfusion pressures in a porcine model of cardiac arrest.

Yannopoulos D, Nadkarni VM, McKnite SH, Rao A, Kruger K, Metzger A, Benditt DG, Lurie KG.

Circulation. 2005 Aug 9;112(6):803-11. Epub 2005 Aug 1.


From laboratory science to six emergency medical services systems: New understanding of the physiology of cardiopulmonary resuscitation increases survival rates after cardiac arrest.

Aufderheide TP, Alexander C, Lick C, Myers B, Romig L, Vartanian L, Stothert J, McKnite S, Matsuura T, Yannopoulos D, Lurie K.

Crit Care Med. 2008 Nov;36(11 Suppl):S397-404.


Evaluation of the Boussignac Cardiac arrest device (B-card) during cardiopulmonary resuscitation in an animal model.

Moore JC, Lamhaut L, Hutin A, Dodd KW, Robinson AE, Lick MC, Salverda BJ, Hinke MB, Labarere J, Debaty G, Segal N.

Resuscitation. 2017 Oct;119:81-88. doi: 10.1016/j.resuscitation.2017.08.004. Epub 2017 Aug 9.


Effects of head-up vs. supine CPR on cerebral oxygenation and cerebral metabolism - a prospective, randomized porcine study.

Putzer G, Braun P, Martini J, Niederstätter I, Abram J, Lindner AK, Neururer S, Mulino M, Glodny B, Helbok R, Mair P.

Resuscitation. 2018 Jul;128:51-55. doi: 10.1016/j.resuscitation.2018.04.038. Epub 2018 May 1.


Effect of continuous compression and 30:2 cardiopulmonary resuscitation on cerebral microcirculation in a porcine model of cardiac arrest.

Yang L, Wang S, Li CS.

Scand J Trauma Resusc Emerg Med. 2013 Jul 12;21:55. doi: 10.1186/1757-7241-21-55.


Sodium nitroprusside enhanced cardiopulmonary resuscitation prevents post-resuscitation left ventricular dysfunction and improves 24-hour survival and neurological function in a porcine model of prolonged untreated ventricular fibrillation.

Schultz J, Segal N, Kolbeck J, Caldwell E, Thorsgard M, McKnite S, Aufderheide TP, Lurie KG, Yannopoulos D.

Resuscitation. 2011 Dec;82 Suppl 2:S35-40. doi: 10.1016/S0300-9572(11)70149-6.

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