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Items: 1 to 20 of 230

1.

Urolithin A alleviates myocardial ischemia/reperfusion injury via PI3K/Akt pathway.

Tang L, Mo Y, Li Y, Zhong Y, He S, Zhang Y, Tang Y, Fu S, Wang X, Chen A.

Biochem Biophys Res Commun. 2017 May 6;486(3):774-780. doi: 10.1016/j.bbrc.2017.03.119. Epub 2017 Mar 23.

PMID:
28343995
2.
3.

Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathway.

Zhang MQ, Zheng YL, Chen H, Tu JF, Shen Y, Guo JP, Yang XH, Yuan SR, Chen LZ, Chai JJ, Lu JH, Zhai CL.

Acta Pharmacol Sin. 2013 Nov;34(11):1386-96. doi: 10.1038/aps.2013.91. Epub 2013 Sep 30.

4.

Shikonin protects H9C2 cardiomyocytes against hypoxia/reoxygenation injury through activation of PI3K/Akt signaling pathway.

Wang S, Zhu Y, Qiu R.

Biomed Pharmacother. 2018 Aug;104:712-717. doi: 10.1016/j.biopha.2018.04.144. Epub 2018 May 25.

PMID:
29807220
5.

Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion.

Song JQ, Teng X, Cai Y, Tang CS, Qi YF.

Apoptosis. 2009 Sep;14(9):1061-9. doi: 10.1007/s10495-009-0382-2.

PMID:
19634012
6.

Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway.

Zeng C, Jiang W, Zheng R, He C, Li J, Xing J.

PLoS One. 2018 Mar 14;13(3):e0193845. doi: 10.1371/journal.pone.0193845. eCollection 2018.

7.

Protective effect of urantide against ischemia-reperfusion injury via protein kinase C and phosphtidylinositol 3'-kinase - Akt pathway.

Zhang JY, Chen ZW, Yao H.

Can J Physiol Pharmacol. 2012 May;90(5):637-45. doi: 10.1139/y2012-048. Epub 2012 Apr 27.

PMID:
22537485
8.

Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol.

Thomas CJ, Lim NR, Kedikaetswe A, Yeap YY, Woodman OL, Ng DC, May CN.

Eur J Pharmacol. 2015 Jul 5;758:53-9. doi: 10.1016/j.ejphar.2015.03.054. Epub 2015 Mar 25.

PMID:
25820159
9.

Luteolin inhibits apoptosis and improves cardiomyocyte contractile function through the PI3K/Akt pathway in simulated ischemia/reperfusion.

Fang F, Li D, Pan H, Chen D, Qi L, Zhang R, Sun H.

Pharmacology. 2011;88(3-4):149-58. doi: 10.1159/000330068. Epub 2011 Sep 16.

PMID:
21934351
10.

Hesperetin post-treatment prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating PI3K/Akt signaling pathway.

He S, Wang X, Zhong Y, Tang L, Zhang Y, Ling Y, Tan Z, Yang P, Chen A.

Biomed Pharmacother. 2017 Jul;91:1106-1112. doi: 10.1016/j.biopha.2017.05.003. Epub 2017 May 16.

PMID:
28531921
12.

Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway.

He F, Xu BL, Chen C, Jia HJ, Wu JX, Wang XC, Sheng JL, Huang L, Cheng J.

Acta Pharmacol Sin. 2016 Jun;37(6):763-71. doi: 10.1038/aps.2016.14. Epub 2016 Apr 11.

14.

Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo.

Chen L, Liu P, Feng X, Ma C.

J Cell Mol Med. 2017 Dec;21(12):3178-3189. doi: 10.1111/jcmm.12871. Epub 2017 Sep 14.

15.

Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia‑reperfusion injury via upregulation of the PI3K/Akt pathway.

Zhou Z, Zhang Y, Lin L, Zhou J.

Mol Med Rep. 2018 Aug;18(2):1560-1570. doi: 10.3892/mmr.2018.9115. Epub 2018 May 31.

16.

Nerve growth factor protects the ischemic heart via attenuation of the endoplasmic reticulum stress induced apoptosis by activation of phosphatidylinositol 3-kinase.

Wei K, Liu L, Xie F, Hao X, Luo J, Min S.

Int J Med Sci. 2015 Jan 1;12(1):83-91. doi: 10.7150/ijms.10101. eCollection 2015.

17.

Aqueous extract of Cortex Dictamni protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress and apoptosis by PI3K/Akt signaling pathway.

Li L, Zhou Y, Li Y, Wang L, Sun L, Zhou L, Arai H, Qi Y, Xu Y.

Biomed Pharmacother. 2017 May;89:233-244. doi: 10.1016/j.biopha.2017.02.013. Epub 2017 Mar 24.

PMID:
28231545
18.

Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway.

Wu MP, Zhang YS, Zhou QM, Xiong J, Dong YR, Yan C.

Pharmacol Res. 2016 Feb;104:115-23. doi: 10.1016/j.phrs.2015.12.032. Epub 2015 Dec 30.

19.

25-Hydroxyl-protopanaxatriol protects against H2O2-induced H9c2 cardiomyocytes injury via PI3K/Akt pathway and apoptotic protein down-regulation.

Wang Z, Su G, Zhang Z, Dong H, Wang Y, Zhao H, Zhao Y, Sun Q.

Biomed Pharmacother. 2018 Mar;99:33-42. doi: 10.1016/j.biopha.2018.01.039. Epub 2018 Jan 8.

PMID:
29324310
20.

α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway.

Deng C, Sun Z, Tong G, Yi W, Ma L, Zhao B, Cheng L, Zhang J, Cao F, Yi D.

PLoS One. 2013;8(3):e58371. doi: 10.1371/journal.pone.0058371. Epub 2013 Mar 7.

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