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Items: 1 to 20 of 101

1.

Hsp90 regulation of fibroblast activation in pulmonary fibrosis.

Sontake V, Wang Y, Kasam RK, Sinner D, Reddy GB, Naren AP, McCormack FX, White ES, Jegga AG, Madala SK.

JCI Insight. 2017 Feb 23;2(4):e91454. doi: 10.1172/jci.insight.91454.

2.

MK2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis.

Liang J, Liu N, Liu X, Monterrosa Mena J, Xie T, Geng Y, Huan C, Zhang Y, Taghavifar F, Huang G, Kurkciyan A, Barron V, Jiang D, Noble PW.

Am J Respir Cell Mol Biol. 2018 Aug 21. doi: 10.1165/rcmb.2018-0033OC. [Epub ahead of print]

PMID:
30130411
3.

Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis Fibroblasts.

Mullenbrock S, Liu F, Szak S, Hronowski X, Gao B, Juhasz P, Sun C, Liu M, McLaughlin H, Xiao Q, Feghali-Bostwick C, Zheng TS.

Genes (Basel). 2018 Nov 29;9(12). pii: E588. doi: 10.3390/genes9120588.

4.

Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis.

Shimbori C, Bellaye PS, Xia J, Gauldie J, Ask K, Ramos C, Becerril C, Pardo A, Selman M, Kolb M.

J Pathol. 2016 Oct;240(2):197-210. doi: 10.1002/path.4768.

PMID:
27425145
5.

FGF9 and FGF18 in idiopathic pulmonary fibrosis promote survival and migration and inhibit myofibroblast differentiation of human lung fibroblasts in vitro.

Joannes A, Brayer S, Besnard V, Marchal-Sommé J, Jaillet M, Mordant P, Mal H, Borie R, Crestani B, Mailleux AA.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L615-29. doi: 10.1152/ajplung.00185.2015. Epub 2016 Jan 15.

6.

Wilms' tumor 1 drives fibroproliferation and myofibroblast transformation in severe fibrotic lung disease.

Sontake V, Kasam RK, Sinner D, Korfhagen TR, Reddy GB, White ES, Jegga AG, Madala SK.

JCI Insight. 2018 Aug 23;3(16). pii: 121252. doi: 10.1172/jci.insight.121252. [Epub ahead of print]

7.

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.

Oruqaj G, Karnati S, Vijayan V, Kotarkonda LK, Boateng E, Zhang W, Ruppert C, Günther A, Shi W, Baumgart-Vogt E.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2048-57. doi: 10.1073/pnas.1415111112. Epub 2015 Apr 6.

8.

Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis.

Philp CJ, Siebeke I, Clements D, Miller S, Habgood A, John AE, Navaratnam V, Hubbard RB, Jenkins G, Johnson SR.

Am J Respir Cell Mol Biol. 2018 May;58(5):594-603. doi: 10.1165/rcmb.2016-0379OC.

PMID:
29053339
9.
10.

PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition.

Conte E, Gili E, Fruciano M, Korfei M, Fagone E, Iemmolo M, Lo Furno D, Giuffrida R, Crimi N, Guenther A, Vancheri C.

Lab Invest. 2013 May;93(5):566-76. doi: 10.1038/labinvest.2013.6. Epub 2013 Feb 25.

11.

Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis.

Warsinske HC, Wheaton AK, Kim KK, Linderman JJ, Moore BB, Kirschner DE.

Front Pharmacol. 2016 Jun 23;7:183. doi: 10.3389/fphar.2016.00183. eCollection 2016.

12.

Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis.

Machahua C, Montes-Worboys A, Llatjos R, Escobar I, Dorca J, Molina-Molina M, Vicens-Zygmunt V.

Respir Res. 2016 Nov 5;17(1):144.

13.

Dicer1 Deficiency in the Idiopathic Pulmonary Fibrosis Fibroblastic Focus Promotes Fibrosis by Suppressing MicroRNA Biogenesis.

Herrera J, Beisang DJ, Peterson M, Forster C, Gilbertsen A, Benyumov A, Smith K, Korenczuk CE, Barocas VH, Guenther K, Hite R, Zhang L, Henke CA, Bitterman PB.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):486-496. doi: 10.1164/rccm.201709-1823OC.

PMID:
29579397
14.

Novel Differences in Gene Expression and Functional Capabilities of Myofibroblast Populations in Idiopathic Pulmonary Fibrosis.

Walsh SM, Worrell JC, Fabre A, Hinz B, Kane R, Keane MP.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 9. doi: 10.1152/ajplung.00543.2017. [Epub ahead of print]

PMID:
30091381
15.

Lung fibrotic tenascin-C upregulation is associated with other extracellular matrix proteins and induced by TGFβ1.

Estany S, Vicens-Zygmunt V, Llatjós R, Montes A, Penín R, Escobar I, Xaubet A, Santos S, Manresa F, Dorca J, Molina-Molina M.

BMC Pulm Med. 2014 Jul 26;14:120. doi: 10.1186/1471-2466-14-120.

16.

Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.

Luo F, Zhuang Y, Sides MD, Sanchez CG, Shan B, White ES, Lasky JA.

Respir Res. 2014 Apr 24;15:51. doi: 10.1186/1465-9921-15-51.

17.

Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3.

Mackinnon AC, Gibbons MA, Farnworth SL, Leffler H, Nilsson UJ, Delaine T, Simpson AJ, Forbes SJ, Hirani N, Gauldie J, Sethi T.

Am J Respir Crit Care Med. 2012 Mar 1;185(5):537-46. doi: 10.1164/rccm.201106-0965OC. Epub 2011 Nov 17.

18.

Loss of CDKN2B Promotes Fibrosis via Increased Fibroblast Differentiation Rather Than Proliferation.

Scruggs AM, Koh HB, Tripathi P, Leeper NJ, White ES, Huang SK.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):200-214. doi: 10.1165/rcmb.2017-0298OC.

PMID:
29420051
19.

miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1.

Lino Cardenas CL, Henaoui IS, Courcot E, Roderburg C, Cauffiez C, Aubert S, Copin MC, Wallaert B, Glowacki F, Dewaeles E, Milosevic J, Maurizio J, Tedrow J, Marcet B, Lo-Guidice JM, Kaminski N, Barbry P, Luedde T, Perrais M, Mari B, Pottier N.

PLoS Genet. 2013;9(2):e1003291. doi: 10.1371/journal.pgen.1003291. Epub 2013 Feb 14.

20.

Elevated protein arginine methyltransferase 1 expression regulates fibroblast motility in pulmonary fibrosis.

Zakrzewicz D, Zakrzewicz A, Didiasova M, Korencak M, Kosanovic D, Schermuly RT, Markart P, Wygrecka M.

Biochim Biophys Acta. 2015 Dec;1852(12):2678-88. doi: 10.1016/j.bbadis.2015.09.008. Epub 2015 Sep 21.

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