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Management of adults with T-cell lymphoblastic leukemia.

Marks DI, Rowntree C.

Blood. 2017 Mar 2;129(9):1134-1142. doi: 10.1182/blood-2016-07-692608. Epub 2017 Jan 23. Review. Erratum in: Blood. 2017 Apr 13;129(15):2204.


Non-myeloablative conditioning with allogeneic hematopoietic cell transplantation for the treatment of high-risk acute lymphoblastic leukemia.

Ram R, Storb R, Sandmaier BM, Maloney DG, Woolfrey A, Flowers ME, Maris MB, Laport GG, Chauncey TR, Lange T, Langston AA, Storer B, Georges GE.

Haematologica. 2011 Aug;96(8):1113-20. doi: 10.3324/haematol.2011.040261. Epub 2011 Apr 20.


How I treat T-cell acute lymphoblastic leukemia in adults.

Litzow MR, Ferrando AA.

Blood. 2015 Aug 13;126(7):833-41. doi: 10.1182/blood-2014-10-551895. Epub 2015 May 12.


Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients.

Yokota S, Hansen-Hagge TE, Ludwig WD, Reiter A, Raghavachar A, Kleihauer E, Bartram CR.

Blood. 1991 Jan 15;77(2):331-9.


Current treatment of adult acute lymphoblastic leukemia.

Fujisawa S.

Rinsho Ketsueki. 2017;58(10):1983-1994. doi: 10.11406/rinketsu.58.1983. Japanese.


High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation.

Gökbuget N, Basara N, Baurmann H, Beck J, Brüggemann M, Diedrich H, Güldenzoph B, Hartung G, Horst HA, Hüttmann A, Kobbe G, Naumann R, Ratei R, Reichle A, Serve H, Stelljes M, Viardot A, Wattad M, Hoelzer D.

Blood. 2011 Sep 29;118(13):3504-11. doi: 10.1182/blood-2011-01-329441. Epub 2011 Jun 28.


Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.

DeAngelo DJ, Yu D, Johnson JL, Coutre SE, Stone RM, Stopeck AT, Gockerman JP, Mitchell BS, Appelbaum FR, Larson RA.

Blood. 2007 Jun 15;109(12):5136-42. Epub 2007 Mar 7.


Superior survival of unmanipulated haploidentical hematopoietic stem cell transplantation compared with chemotherapy alone used as post-remission therapy in adults with standard-risk acute lymphoblastic leukemia in first complete remission.

Yan CH, Jiang Q, Wang J, Xu LP, Liu DH, Jiang H, Chen H, Zhang XH, Liu KY, Huang XJ.

Biol Blood Marrow Transplant. 2014 Sep;20(9):1314-21. doi: 10.1016/j.bbmt.2014.04.011. Epub 2014 Apr 18.


Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission.

Patel B, Kirkland KE, Szydlo R, Pearce RM, Clark RE, Craddock C, Liakopoulou E, Fielding AK, Mackinnon S, Olavarria E, Potter MN, Russell NH, Shaw BE, Cook G, Goldstone AH, Marks DI.

Haematologica. 2009 Oct;94(10):1399-406. doi: 10.3324/haematol.2009.008649. Epub 2009 Jul 31.


FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma.

Cohen MH, Johnson JR, Justice R, Pazdur R.

Oncologist. 2008 Jun;13(6):709-14. doi: 10.1634/theoncologist.2006-0017.


Outcomes of Adults with Acute Lymphoblastic Leukemia After Autologous Hematopoietic Stem Cell Transplantation and the Significance of Pretransplantation Minimal Residual Disease: Analysis from a Single Center of China.

Ding Z, Han MZ, Chen SL, Ma QL, Wei JL, Pang AM, Zhang XY, Liang C, Yao JF, Cao YG, Feng SZ, Jiang EL.

Chin Med J (Engl). 2015 Aug 5;128(15):2065-71. doi: 10.4103/0366-6999.161365.


Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia.

Heesch S, Goekbuget N, Stroux A, Tanchez JO, Schlee C, Burmeister T, Schwartz S, Blau O, Keilholz U, Busse A, Hoelzer D, Thiel E, Hofmann WK, Baldus CD.

Haematologica. 2010 Jun;95(6):942-9. doi: 10.3324/haematol.2009.016386. Epub 2010 Apr 30.


T-cell receptor gamma and delta junctional gene rearrangements as diagnostic and prognostic biomarker for T-cell acute lymphoblastic leukemia.

Kode J, Dudhal N, Banavali S, Chiplunkar S.

Leuk Lymphoma. 2006 Apr;47(4):769-70. No abstract available.


CNS-directed therapy in young children with T-lineage acute lymphoblastic leukemia: High-dose methotrexate versus cranial irradiation.

Nathan PC, Maze R, Spiegler B, Greenberg ML, Weitzman S, Hitzler JK.

Pediatr Blood Cancer. 2004 Jan;42(1):24-9.


Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.

Zuurbier L, Gutierrez A, Mullighan CG, Canté-Barrett K, Gevaert AO, de Rooi J, Li Y, Smits WK, Buijs-Gladdines JG, Sonneveld E, Look AT, Horstmann M, Pieters R, Meijerink JP.

Haematologica. 2014 Jan;99(1):94-102. doi: 10.3324/haematol.2013.090233. Epub 2013 Aug 23.


Long-term follow-up of patients with newly diagnosed adult acute lymphoblastic leukemia: a single institution experience of 378 consecutive patients over a 21-year period.

Thomas X, Danaïla C, Le QH, Sebban C, Troncy J, Charrin C, Lhéritier V, Michallet M, Magaud JP, Fiere D.

Leukemia. 2001 Dec;15(12):1811-22.


A case of pediatric γ/δ T-cell malignancy with t(8;14)(q24;q11)/MYC-TCR successfully treated with pulse type chemotherapy followed by stem cell transplant.

Morales La Madrid A, Ouyang K, Raca G, Jamali M, Hyjek E, McNeer JL, Anastasi J.

Leuk Lymphoma. 2013 Feb;54(2):403-5. doi: 10.3109/10428194.2012.708930. Epub 2012 Aug 14. No abstract available.


Nelarabine for the treatment of patients with relapsed or refractory T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma.

DeAngelo DJ.

Hematol Oncol Clin North Am. 2009 Oct;23(5):1121-35, vii-viii. doi: 10.1016/j.hoc.2009.07.008. Review.


[The clinical and laboratory features of 9 cases with gammadeltaT cell lymphoma or leukemia].

Tong CR, Wang H, Lin YH, Yang JF, Zhao J, Zhang X, Yin YM, Fei XH, Wu P, Wang T, Liu HX, Cai P, Wei ZJ, Xiao J, Liu DY, Xiong M, Zhong J, Lu DP.

Zhonghua Xue Ye Xue Za Zhi. 2011 Jul;32(7):445-9. Chinese.


Guidelines for the management of mature T-cell and NK-cell neoplasms (excluding cutaneous T-cell lymphoma).

Dearden CE, Johnson R, Pettengell R, Devereux S, Cwynarski K, Whittaker S, McMillan A; British Committee for Standards in Haematology.

Br J Haematol. 2011 May;153(4):451-85. doi: 10.1111/j.1365-2141.2011.08651.x. Epub 2011 Apr 11. Review.


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