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Items: 1 to 20 of 157

1.

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.

Dunlop EA, Seifan S, Claessens T, Behrends C, Kamps MA, Rozycka E, Kemp AJ, Nookala RK, Blenis J, Coull BJ, Murray JT, van Steensel MA, Wilkinson S, Tee AR.

Autophagy. 2014 Oct 1;10(10):1749-60. doi: 10.4161/auto.29640. Epub 2014 Jul 22.

2.

Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.

Hasumi H, Baba M, Hasumi Y, Furuya M, Yao M.

Int J Urol. 2016 Mar;23(3):204-10. doi: 10.1111/iju.13015. Epub 2015 Nov 25. Review.

3.

Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression.

Nagashima K, Fukushima H, Shimizu K, Yamada A, Hidaka M, Hasumi H, Ikebe T, Fukumoto S, Okabe K, Inuzuka H.

Oncotarget. 2017 Feb 7;8(6):9947-9960. doi: 10.18632/oncotarget.14221.

4.

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.

Baba M, Hong SB, Sharma N, Warren MB, Nickerson ML, Iwamatsu A, Esposito D, Gillette WK, Hopkins RF 3rd, Hartley JL, Furihata M, Oishi S, Zhen W, Burke TR Jr, Linehan WM, Schmidt LS, Zbar B.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15552-7. Epub 2006 Oct 6.

5.

Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.

Takagi Y, Kobayashi T, Shiono M, Wang L, Piao X, Sun G, Zhang D, Abe M, Hagiwara Y, Takahashi K, Hino O.

Oncogene. 2008 Sep 11;27(40):5339-47. doi: 10.1038/onc.2008.261. Epub 2008 Jul 28.

PMID:
18663353
6.

Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates.

Lim J, Lachenmayer ML, Wu S, Liu W, Kundu M, Wang R, Komatsu M, Oh YJ, Zhao Y, Yue Z.

PLoS Genet. 2015 Feb 27;11(2):e1004987. doi: 10.1371/journal.pgen.1004987. eCollection 2015.

7.

Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.

Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M.

Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):1-12.

PMID:
11146101
8.

Physical exercise increases autophagic signaling through ULK1 in human skeletal muscle.

Møller AB, Vendelbo MH, Christensen B, Clasen BF, Bak AM, Jørgensen JO, Møller N, Jessen N.

J Appl Physiol (1985). 2015 Apr 15;118(8):971-9. doi: 10.1152/japplphysiol.01116.2014. Epub 2015 Feb 12.

9.

FLCN: The causative gene for Birt-Hogg-Dubé syndrome.

Schmidt LS, Linehan WM.

Gene. 2018 Jan 15;640:28-42. doi: 10.1016/j.gene.2017.09.044. Epub 2017 Sep 29. Review.

PMID:
28970150
10.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
11.

Birt-Hogg-Dube syndrome: clinicopathological features of the lung.

Furuya M, Nakatani Y.

J Clin Pathol. 2013 Mar;66(3):178-86. doi: 10.1136/jclinpath-2012-201200. Epub 2012 Dec 8. Review.

12.

Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1.

Ro SH, Semple IA, Park H, Park H, Park HW, Kim M, Kim JS, Lee JH.

FEBS J. 2014 Sep;281(17):3816-27. doi: 10.1111/febs.12905. Epub 2014 Jul 28.

13.

Clinical Features, Genetics and Potential Therapeutic Approaches for Birt-Hogg-Dubé Syndrome.

Schmidt LS, Linehan WM.

Expert Opin Orphan Drugs. 2015;3(1):15-29. Epub 2014 Nov 29.

14.

Mechanisms of pulmonary cyst pathogenesis in Birt-Hogg-Dube syndrome: The stretch hypothesis.

Kennedy JC, Khabibullin D, Henske EP.

Semin Cell Dev Biol. 2016 Apr;52:47-52. doi: 10.1016/j.semcdb.2016.02.014. Epub 2016 Feb 10. Review.

PMID:
26877139
15.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

16.

Birt-Hogg-Dubé syndrome: from gene discovery to molecularly targeted therapies.

Schmidt LS.

Fam Cancer. 2013 Sep;12(3):357-64. doi: 10.1007/s10689-012-9574-y. Erratum in: Fam Cancer. 2013 Sep;12(3):365.

17.

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X.

J Biol Chem. 2009 May 1;284(18):12297-305. doi: 10.1074/jbc.M900573200. Epub 2009 Mar 3.

18.

Identification and characterization of a novel folliculin-interacting protein FNIP2.

Hasumi H, Baba M, Hong SB, Hasumi Y, Huang Y, Yao M, Valera VA, Linehan WM, Schmidt LS.

Gene. 2008 May 31;415(1-2):60-7. doi: 10.1016/j.gene.2008.02.022. Epub 2008 Mar 4.

19.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

20.

Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.

Furuya M, Hong SB, Tanaka R, Kuroda N, Nagashima Y, Nagahama K, Suyama T, Yao M, Nakatani Y.

Cancer Sci. 2015 Mar;106(3):315-23. doi: 10.1111/cas.12601. Epub 2015 Feb 17.

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