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Items: 1 to 20 of 101

1.

The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion.

Iwata TN, Cowley TJ, Sloma M, Ji Y, Kim H, Qi L, Lee SS.

PLoS One. 2013 Nov 8;8(11):e78841. doi: 10.1371/journal.pone.0078841. eCollection 2013.

2.

SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice.

Chen Z, Morris DL, Jiang L, Liu Y, Rui L.

Mol Endocrinol. 2014 May;28(5):696-705. doi: 10.1210/me.2013-1333. Epub 2014 Mar 19.

3.

SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.

Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J.

J Biol Chem. 2005 Nov 11;280(45):37669-80. Epub 2005 Sep 7.

4.

Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1).

Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, Zhang F, Ding X, Wang C, Xiong S, Wang Z, Yuan J, Li Q, Zhang Y.

J Biol Chem. 2013 Jun 14;288(24):17532-43. doi: 10.1074/jbc.M112.439729. Epub 2013 Apr 29.

5.

Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas.

Mwangi SM, Usta Y, Raja SM, Anitha M, Chandrasekharan B, Parsadanian A, Sitaraman SV, Srinivasan S.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G283-92. doi: 10.1152/ajpgi.00096.2010. Epub 2010 May 6.

6.

Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA.

Akinci E, Banga A, Greder LV, Dutton JR, Slack JM.

Biochem J. 2012 Mar 15;442(3):539-50. doi: 10.1042/BJ20111678.

7.

E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases.

Tyagi S, Herr W.

EMBO J. 2009 Oct 21;28(20):3185-95. doi: 10.1038/emboj.2009.258. Epub 2009 Sep 17.

8.

Islet-1 Is essential for pancreatic β-cell function.

Ediger BN, Du A, Liu J, Hunter CS, Walp ER, Schug J, Kaestner KH, Stein R, Stoffers DA, May CL.

Diabetes. 2014 Dec;63(12):4206-17. doi: 10.2337/db14-0096. Epub 2014 Jul 15.

9.

Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus.

Szabat M, Luciani DS, Piret JM, Johnson JD.

Endocrinology. 2009 Apr;150(4):1627-35. doi: 10.1210/en.2008-1224. Epub 2008 Dec 18.

PMID:
19095744
10.

Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner.

Macfarlane WM, Campbell SC, Elrick LJ, Oates V, Bermano G, Lindley KJ, Aynsley-Green A, Dunne MJ, James RF, Docherty K.

J Biol Chem. 2000 May 19;275(20):15330-5.

11.

The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.

Kim SY, Rane SG.

Development. 2011 May;138(10):1903-12. doi: 10.1242/dev.061481. Epub 2011 Apr 13.

12.

Tshz1 Regulates Pancreatic β-Cell Maturation.

Raum JC, Soleimanpour SA, Groff DN, Coré N, Fasano L, Garratt AN, Dai C, Powers AC, Stoffers DA.

Diabetes. 2015 Aug;64(8):2905-14. doi: 10.2337/db14-1443. Epub 2015 Apr 27.

13.

Microphthalmia transcription factor regulates pancreatic β-cell function.

Mazur MA, Winkler M, Ganic E, Colberg JK, Johansson JK, Bennet H, Fex M, Nuber UA, Artner I.

Diabetes. 2013 Aug;62(8):2834-42. doi: 10.2337/db12-1464. Epub 2013 Apr 22.

14.

Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.

Bao S, Jacobson DA, Wohltmann M, Bohrer A, Jin W, Philipson LH, Turk J.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E217-29. Epub 2007 Sep 25.

15.

An emerging model for BAP1's role in regulating cell cycle progression.

Eletr ZM, Wilkinson KD.

Cell Biochem Biophys. 2011 Jun;60(1-2):3-11. doi: 10.1007/s12013-011-9184-6. Review.

16.

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7297-302. Epub 2005 May 9.

17.

Hedgehog signaling regulation of homeodomain protein islet duodenum homeobox-1 expression in pancreatic beta-cells.

Thomas MK, Lee JH, Rastalsky N, Habener JF.

Endocrinology. 2001 Mar;142(3):1033-40.

PMID:
11181516
18.

Differentiation of Mouse Embryonic Stem Cells toward Functional Pancreatic β-Cell Surrogates through Epigenetic Regulation of Pdx1 by Nitric Oxide.

Salguero-Aranda C, Tapia-Limonchi R, Cahuana GM, Hitos AB, Diaz I, Hmadcha A, Fraga M, Martín F, Soria B, Tejedo JR, Bedoya FJ.

Cell Transplant. 2016 Oct;25(10):1879-1892. doi: 10.3727/096368916X691178.

PMID:
26980118
19.

Regulation of the pdx1 gene promoter in pancreatic beta-cells.

Campbell SC, Macfarlane WM.

Biochem Biophys Res Commun. 2002 Nov 29;299(2):277-84.

PMID:
12437983
20.

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets.

Dai C, Brissova M, Hang Y, Thompson C, Poffenberger G, Shostak A, Chen Z, Stein R, Powers AC.

Diabetologia. 2012 Mar;55(3):707-18. doi: 10.1007/s00125-011-2369-0. Epub 2011 Dec 14.

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