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Src homology-2 domain-containing protein tyrosine phosphatase (SHP) 2 and p38 regulate the expression of chemokine CXCL8 in human astrocytes.

Mamik MK, Ghorpade A.

PLoS One. 2012;7(9):e45596. doi: 10.1371/journal.pone.0045596. Epub 2012 Sep 21.


HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1beta and TNF-alpha: involvement of mitogen-activated protein kinases and protein kinase R.

Zheng JC, Huang Y, Tang K, Cui M, Niemann D, Lopez A, Morgello S, Chen S.

J Neuroimmunol. 2008 Aug 30;200(1-2):100-10. doi: 10.1016/j.jneuroim.2008.06.015. Epub 2008 Jul 23.


HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms.

Mamik MK, Banerjee S, Walseth TF, Hirte R, Tang L, Borgmann K, Ghorpade A.

J Neuroinflammation. 2011 Oct 25;8:145. doi: 10.1186/1742-2094-8-145.


Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signaling pathways.

Wanninger J, Neumeier M, Weigert J, Bauer S, Weiss TS, Schäffler A, Krempl C, Bleyl C, Aslanidis C, Schölmerich J, Buechler C.

Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G611-8. doi: 10.1152/ajpgi.90644.2008. Epub 2009 Jul 16. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2012 Feb;302(3):G406.


SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.

Schmitz J, Weissenbach M, Haan S, Heinrich PC, Schaper F.

J Biol Chem. 2000 Apr 28;275(17):12848-56.


Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected].

Thompson WL, Van Eldik LJ.

Brain Res. 2009 Sep 1;1287:47-57. doi: 10.1016/j.brainres.2009.06.081. Epub 2009 Jul 3. Erratum in: Brain Res. 2009 Oct 27;1295:230.


Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.

Anhuf D, Weissenbach M, Schmitz J, Sobota R, Hermanns HM, Radtke S, Linnemann S, Behrmann I, Heinrich PC, Schaper F.

J Immunol. 2000 Sep 1;165(5):2535-43.


Hemin inhibits NO production by IL-1β-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation.

Sheng WS, Hu S, Nettles AR, Lokensgard JR, Vercellotti GM, Rock RB.

J Neuroinflammation. 2010 Sep 7;7:51. doi: 10.1186/1742-2094-7-51.


Role of C/EBP-β, p38 MAPK, and MKK6 in IL-1β-mediated C3 gene regulation in astrocytes.

Maranto J, Rappaport J, Datta PK.

J Cell Biochem. 2011 Apr;112(4):1168-75. doi: 10.1002/jcb.23032.


SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells.

McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW.

J Immunol. 2009 Oct 15;183(8):4940-7. doi: 10.4049/jimmunol.0900702. Epub 2009 Sep 28.


Extracellular regulated kinase 1/2 signaling is a critical regulator of interleukin-1β-mediated astrocyte tissue inhibitor of metalloproteinase-1 expression.

Fields J, Cisneros IE, Borgmann K, Ghorpade A.

PLoS One. 2013;8(2):e56891. doi: 10.1371/journal.pone.0056891. Epub 2013 Feb 14.

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