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Items: 1 to 20 of 178

1.

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I.

Mol Cell Biol. 2012 May;32(9):1733-44. doi: 10.1128/MCB.06717-11. Epub 2012 Feb 21.

2.

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I.

Mol Cell. 2015 Jan 8;57(1):39-54. doi: 10.1016/j.molcel.2014.11.006. Epub 2014 Dec 11.

3.

The LIR motif - crucial for selective autophagy.

Birgisdottir ÅB, Lamark T, Johansen T.

J Cell Sci. 2013 Aug 1;126(Pt 15):3237-47. doi: 10.1242/jcs.126128. Review.

4.

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.

Yamano K, Fogel AI, Wang C, van der Bliek AM, Youle RJ.

Elife. 2014 Feb 25;3:e01612. doi: 10.7554/eLife.01612.

5.

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.

J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.

6.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

7.

Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins.

Johansen T, Birgisdottir ÅB, Huber J, Kniss A, Dötsch V, Kirkin V, Rogov VV.

Methods Enzymol. 2017;587:143-169. doi: 10.1016/bs.mie.2016.10.023. Epub 2017 Jan 12.

PMID:
28253953
8.

The integration of autophagy and cellular trafficking pathways via RAB GAPs.

Kern A, Dikic I, Behl C.

Autophagy. 2015;11(12):2393-7. doi: 10.1080/15548627.2015.1110668. Review.

9.

Analysis of the native conformation of the LIR/AIM motif in the Atg8/LC3/GABARAP-binding proteins.

Popelka H, Klionsky DJ.

Autophagy. 2015;11(12):2153-9. doi: 10.1080/15548627.2015.1111503.

10.

TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy.

Popovic D, Dikic I.

EMBO Rep. 2014 Apr;15(4):392-401. doi: 10.1002/embr.201337995. Epub 2014 Mar 6.

11.

Accessory Interaction Motifs in the Atg19 Cargo Receptor Enable Strong Binding to the Clustered Ubiquitin-related Atg8 Protein.

Abert C, Kontaxis G, Martens S.

J Biol Chem. 2016 Sep 2;291(36):18799-808. doi: 10.1074/jbc.M116.736892. Epub 2016 Jul 11.

12.

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.

Seillier M, Peuget S, Gayet O, Gauthier C, N'Guessan P, Monte M, Carrier A, Iovanna JL, Dusetti NJ.

Cell Death Differ. 2012 Sep;19(9):1525-35. doi: 10.1038/cdd.2012.30. Epub 2012 Mar 16.

13.

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5.

Jia D, Zhang JS, Li F, Wang J, Deng Z, White MA, Osborne DG, Phillips-Krawczak C, Gomez TS, Li H, Singla A, Burstein E, Billadeau DD, Rosen MK.

Nat Commun. 2016 Nov 9;7:13305. doi: 10.1038/ncomms13305.

14.

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets.

Lamark T, Kirkin V, Dikic I, Johansen T.

Cell Cycle. 2009 Jul 1;8(13):1986-90. Epub 2009 Jul 30.

PMID:
19502794
15.

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.

Seaman MN, Harbour ME, Tattersall D, Read E, Bright N.

J Cell Sci. 2009 Jul 15;122(Pt 14):2371-82. doi: 10.1242/jcs.048686. Epub 2009 Jun 16.

16.

Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.

Jimenez-Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, Steinberg F.

EMBO J. 2018 Jan 17;37(2):235-254. doi: 10.15252/embj.201797128. Epub 2017 Nov 20.

17.

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.

Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C.

Autophagy. 2014;10(12):2297-309. doi: 10.4161/15548627.2014.994359.

18.

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.

Longatti A, Lamb CA, Razi M, Yoshimura S, Barr FA, Tooze SA.

J Cell Biol. 2012 May 28;197(5):659-75. doi: 10.1083/jcb.201111079. Epub 2012 May 21.

19.

The LC3 interactome at a glance.

Wild P, McEwan DG, Dikic I.

J Cell Sci. 2014 Jan 1;127(Pt 1):3-9. doi: 10.1242/jcs.140426. Epub 2013 Dec 17. Review.

20.

iLIR: A web resource for prediction of Atg8-family interacting proteins.

Kalvari I, Tsompanis S, Mulakkal NC, Osgood R, Johansen T, Nezis IP, Promponas VJ.

Autophagy. 2014 May;10(5):913-25. doi: 10.4161/auto.28260. Epub 2014 Feb 26.

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